Search Results - "Sink, Alexandra"
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Fatty Acid–Derived Aliphatic Long Chain Polyethers by a Combination of Catalytic Ester Reduction and ADMET or Thiol‐Ene Polymerization
Published in Macromolecular chemistry and physics (01-02-2019)“…Aliphatic long‐chain polyesters are a common class of renewable polymers and can be obtained by various synthetic routes, most notably from renewable fatty…”
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Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition in Vitro and Enable Restoration of Cognition in an Alzheimer’s Disease Mouse Model upon Irradiation
Published in Journal of the American Chemical Society (23-02-2022)“…To develop tools to investigate the biological functions of butyrylcholinesterase (BChE) and the mechanisms by which BChE affects Alzheimer’s disease (AD), we…”
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"Photo-Adrenalines": Photoswitchable β 2 -Adrenergic Receptor Agonists as Molecular Probes for the Study of Spatiotemporal Adrenergic Signaling
Published in Chemistry : a European journal (11-01-2024)“…β -adrenergic receptor (β -AR) agonists are used for the treatment of asthma and chronic obstructive pulmonary disease, but also play a role in other complex…”
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“Photo‐Adrenalines”: Photoswitchable β2‐Adrenergic Receptor Agonists as Molecular Probes for the Study of Spatiotemporal Adrenergic Signaling
Published in Chemistry : a European journal (21-02-2024)“…β2‐adrenergic receptor (β2‐AR) agonists are used for the treatment of asthma and chronic obstructive pulmonary disease, but also play a role in other complex…”
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Photopharmacology on Acetylcholinesterase: Novel Photoswitchable Inhibitors with Improved Pharmacological Profiles
Published in ChemPhotoChem (01-02-2021)“…Considerable effort has previously been invested in a light‐controlled inhibition of the enzyme acetylcholinesterase (AChE). We found that a novel…”
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