Search Results - "Sinitsky, Maxim"

Proteomic Profiling of Endothelial Cells Exposed to Mitomycin C: Key Proteins and Pathways Underlying Genotoxic Stress-Induced Endothelial Dysfunction by Sinitsky, Maxim, Repkin, Egor, Sinitskaya, Anna, Markova, Victoria, Shishkova, Daria, Barbarash, Olga

“…Mitomycin C (MMC)-induced genotoxic stress can be considered to be a novel trigger of endothelial dysfunction and atherosclerosis-a leading cause of…”
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Atorvastatin Can Modulate DNA Damage Repair in Endothelial Cells Exposed to Mitomycin C by Sinitsky, Maxim, Asanov, Maxim, Sinitskaya, Anna, Shishkova, Daria, Khutornaya, Maria, Minina, Varvara, Ponasenko, Anastasia

“…HMG-CoA reductase inhibitors (statins) are widely used in the therapy of atherosclerosis and have a number of pleiotropic effects, including DNA repair…”
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Calcium Phosphate Bions Cause Intimal Hyperplasia in Intact Aortas of Normolipidemic Rats through Endothelial Injury by Shishkova, Daria, Velikanova, Elena, Sinitsky, Maxim, Tsepokina, Anna, Gruzdeva, Olga, Bogdanov, Leo, Kutikhin, Anton

“…Calcium phosphate bions (CPBs) are formed under blood supersaturation with calcium and phosphate owing to the mineral chaperone fetuin-A and representing…”
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Calciprotein Particles Cause Physiologically Significant Pro-Inflammatory Response in Endothelial Cells and Systemic Circulation by Shishkova, Daria, Lobov, Arseniy, Zainullina, Bozhana, Matveeva, Vera, Markova, Victoria, Sinitskaya, Anna, Velikanova, Elena, Sinitsky, Maxim, Kanonykina, Anastasia, Dyleva, Yulia, Kutikhin, Anton

“…Calciprotein particles (CPPs) represent an inherent mineral buffering system responsible for the scavenging of excessive Ca and PO ions in order to prevent…”
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The Role of Polymorphism in the Endothelial Homeostasis and Vitamin D Metabolism Genes in the Severity of Coronary Artery Disease by Ponasenko, Anastasia, Sinitskaya, Anna, Sinitsky, Maxim, Khutornaya, Maria, Barbarash, Olga

“…Coronary artery disease (CAD) remains one of the leading causes of cardiovascular morbidity and mortality worldwide. The maintenance of endothelial homeostasis…”
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Co-Culture of Primary Human Coronary Artery and Internal Thoracic Artery Endothelial Cells Results in Mutually Beneficial Paracrine Interactions by Shishkova, Daria, Markova, Victoria, Sinitsky, Maxim, Tsepokina, Anna, Frolov, Alexey, Zagorodnikov, Nikita, Bogdanov, Leo, Kutikhin, Anton

“…Although saphenous veins (SVs) are commonly used as conduits for coronary artery bypass grafting (CABG), internal thoracic artery (ITA) grafts have…”
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Adipocytes Directly Affect Coronary Artery Disease Pathogenesis via Induction of Adipokine and Cytokine Imbalances by Gruzdeva, Olga, Uchasova, Evgenya, Dyleva, Yulia, Borodkina, Daria, Akbasheva, Olga, Antonova, Larisa, Matveeva, Vera, Belik, Ekaterina, Ivanov, Sergei, Sotnikov, Anton, Kozyrin, Kirill, Brel, Natalia, Sinitsky, Maxim, Karetnikova, Victoria, Kokov, Alexander, Bychkova, Evgenya, Pecherina, Tamara, Barbarash, Olga

“…This study aimed to investigate the adipokine and cytokine profiles of adipocytes from epicardial and subcutaneous adipose tissues in interconnection with the…”
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Calciprotein Particles Induce Cellular Compartment-Specific Proteome Alterations in Human Arterial Endothelial Cells by Shishkova, Daria, Lobov, Arseniy, Repkin, Egor, Markova, Victoria, Markova, Yulia, Sinitskaya, Anna, Sinitsky, Maxim, Kondratiev, Egor, Torgunakova, Evgenia, Kutikhin, Anton

“…Calciprotein particles (CPPs) are indispensable scavengers of excessive Ca and PO ions in blood, being internalised and recycled by liver and spleen…”
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Relationship between Epicardial and Coronary Adipose Tissue and the Expression of Adiponectin, Leptin, and Interleukin 6 in Patients with Coronary Artery Disease by Gruzdeva, Olga V, Dyleva, Yulia A, Belik, Ekaterina V, Sinitsky, Maxim Y, Stasev, Aleksandr N, Kokov, Aleksandr N, Brel, Natalia K, Krivkina, Evgenia O, Bychkova, Evgenia E, Tarasov, Roman S, Barbarash, Olga L

“…Adipose tissue (AT) is an endocrine and paracrine organ that synthesizes biologically active adipocytokines, which affect inflammation, fibrosis, and…”
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DNA excision repair and double-strand break repair gene polymorphisms and the level of chromosome aberration in children with long-term exposure to radon by Larionov, Aleksey V., Sinitsky, Maxim Y., Druzhinin, Vladimir G., Volobaev, Valentin P., Minina, Varvara I., Asanov, Maxim A., Meyer, Alina V., Tolochko, Tatiana A., Kalyuzhnaya, Ekaterina E.

“…Purpose: To study polymorphic variants of repair genes in people affected by long-term exposure to radon. The chromosome aberration frequency in peripheral…”
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Identification of Key Genes and Pathways in Genotoxic Stress Induced Endothelial Dysfunction: Results of Whole Transcriptome Sequencing by Sinitsky, Maxim, Sinitskaya, Anna, Shishkova, Daria, Tupikin, Alexey, Asanov, Maxim, Khutornaya, Maria, Kabilov, Marsel, Ponasenko, Anastasia

“…Atherosclerosis is a leading cause of cardiovascular morbidity and mortality worldwide. Endothelial disfunction underlying the atherogenesis can be triggered…”
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Associations of DNA-repair gene polymorphisms with a genetic susceptibility to ionizing radiation in residents of areas with high radon (222Rn) concentration by Sinitsky, Maxim Y., Larionov, Aleksey V., Asanov, Maxim A., Druzhinin, Vladimir G.

“…Abstract Purpose: To investigate the individual radiosensitivity of the human genome in long-term residents of areas with high radon concentration. Materials…”
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The application of the cytokinesis-block micronucleus assay on peripheral blood lymphocytes for the assessment of genome damage in long-term residents of areas with high radon concentration by Sinitsky, Maxim Yu, Druzhinin, Vladimir G.

“…Estimating the effects of small doses of ionising radiation on DNA is one of the most important problems in modern biology. Different cytogenetic methods exist…”
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Whole-Transcriptome Sequencing: a Powerful Tool for Vascular Tissue Engineering and Endothelial Mechanobiology by Kutikhin, Anton G, Sinitsky, Maxim Yu, Yuzhalin, Arseniy E, Velikanova, Elena A

“…Among applicable high-throughput techniques in cardiovascular biology, whole-transcriptome sequencing is of particular use. By utilizing RNA that is isolated…”
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Expression of adipocytokines in heart fat depots depending on the degree of coronary artery atherosclerosis in patients with coronary artery disease by Gruzdeva, Olga V, Belik, Ekaterina V, Dyleva, Yulia A, Borodkina, Daria A, Sinitsky, Maxim Yu, Naumov, Danil Yu, Bychkova, Evgeniya E, Fanaskova, Elena V, Palicheva, Elena I, Kuzmina, Anastasia A, Karetnikova, Viktoriya N, Barbarash, Olga L

“…In coronary artery disease (CAD) the adipocytokine content in the heart fat depot is altered, but it has not been established whether these changes are…”
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Characteristics of adipocytokine expression by local fat depots of the heart: Relationship with the main risk factors for cardio-vascular diseases by Gruzdeva, Olga V., Dyleva, Yulia A., Belik, Ekaterina V., Sinitsky, Maxim Yu, Kozyrin, Kiril A., Barbarash, Olga L.

“…In our study we investigated the relationships between adipocytokines in adipose tissue (AT) and cardiovascular disease (CVD) risk factors; (2) Methods: fat…”
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Albumin-centric calciprotein particles cause pro-inflammatory endothelial activation by Shishkova, Daria, Markova, Victoria, Markova, Yulia, Sinitskaya, Anna, Sinitsky, Maxim, Velikanova, Elena, Dyleva, Yulia, Kutikhin, Anton

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Endothelial cells of coronary artery and internal thoracic artery are characterised by molecular heterogeneity and functional synergy by Frolov, Alexey, Shishkova, Daria, Markova, Victoria, Sinitskaya, Anna, Sinitsky, Maxim, Lobov, Arseniy, Zainullina, Bozhana, Kabilov, Marsel, Tupikin, Alexey, Kutikhin, Anton

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Calciprotein Particles Cause Endothelial Dysfunction under Flow by Shishkova, Daria, Markova, Victoria, Sinitsky, Maxim, Tsepokina, Anna, Velikanova, Elena, Bogdanov, Leo, Glushkova, Tatiana, Kutikhin, Anton

“…Calciprotein particles (CPPs), which increasingly arise in the circulation during the disorders of mineral homeostasis, represent a double-edged sword…”
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Shear stress: An essential driver of endothelial progenitor cells by Kutikhin, Anton G., Sinitsky, Maxim Yu, Yuzhalin, Arseniy E., Velikanova, Elena A.

“…The blood flow through vessels produces a tangential, or shear, stress sensed by their innermost layer (i.e., endothelium) and representing a major hemodynamic…”
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