Search Results - "Sinitskaya, Anna"
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Mitochondrial DNA as a Candidate Marker of Multiple Organ Failure after Cardiac Surgery
Published in International journal of molecular sciences (25-11-2022)“…Assess the level of mitochondrial DNA depending on the presence of multiple organ failure in patients after heart surgery. The study included 60 patients who…”
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Proteomic Profiling of Endothelial Cells Exposed to Mitomycin C: Key Proteins and Pathways Underlying Genotoxic Stress-Induced Endothelial Dysfunction
Published in International journal of molecular sciences (01-04-2024)“…Mitomycin C (MMC)-induced genotoxic stress can be considered to be a novel trigger of endothelial dysfunction and atherosclerosis-a leading cause of…”
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Atorvastatin Can Modulate DNA Damage Repair in Endothelial Cells Exposed to Mitomycin C
Published in International journal of molecular sciences (01-04-2023)“…HMG-CoA reductase inhibitors (statins) are widely used in the therapy of atherosclerosis and have a number of pleiotropic effects, including DNA repair…”
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TREM-1 as a Marker of Multiple Organ Failure in Cardiac Surgery
Published in Immunological investigations (04-07-2023)“…Systemic inflammatory response syndrome (SIRS) frequently accompanies early postoperative period after cardiac surgery and in some cases is complicated by…”
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Comparison of the Patency and Regenerative Potential of Biodegradable Vascular Prostheses of Different Polymer Compositions in an Ovine Model
Published in International journal of molecular sciences (10-05-2023)“…The lack of suitable autologous grafts and the impossibility of using synthetic prostheses for small artery reconstruction make it necessary to develop…”
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Calciprotein Particles Cause Physiologically Significant Pro-Inflammatory Response in Endothelial Cells and Systemic Circulation
Published in International journal of molecular sciences (29-11-2022)“…Calciprotein particles (CPPs) represent an inherent mineral buffering system responsible for the scavenging of excessive Ca and PO ions in order to prevent…”
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Refraining from Packed Red Blood Cells in Cardiopulmonary Bypass Priming as a Method of Neuroprotection in Pediatric Cardiac Surgery
Published in Journal of clinical medicine (12-02-2023)“…Congenital heart defect (CHD) surgeries are performed with cardiopulmonary bypass (CPB) and are complicated by several factors that affect the child's brain…”
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Multi-Omics Profiling of Human Endothelial Cells from the Coronary Artery and Internal Thoracic Artery Reveals Molecular but Not Functional Heterogeneity
Published in International journal of molecular sciences (01-10-2023)“…Major adverse cardiovascular events occurring upon coronary artery bypass graft surgery are typically accompanied by endothelial dysfunction. Total arterial…”
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The Role of Polymorphism in the Endothelial Homeostasis and Vitamin D Metabolism Genes in the Severity of Coronary Artery Disease
Published in Biomedicines (25-08-2023)“…Coronary artery disease (CAD) remains one of the leading causes of cardiovascular morbidity and mortality worldwide. The maintenance of endothelial homeostasis…”
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Early Postoperative Immunothrombosis of Bioprosthetic Mitral Valve and Left Atrium: A Case Report
Published in International journal of molecular sciences (01-06-2022)“…A 72-year-old female patient with mixed rheumatic mitral valve disease and persistent atrial fibrillation underwent mitral valve replacement and suffered from…”
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The Role of Insulin Resistance in the Development of Complications after Coronary Artery Bypass Grafting in Patients with Coronary Artery Disease
Published in Biomedicines (01-11-2023)“…The aim of the study was to investigate the effect of carbohydrate metabolism disorders and insulin resistance indices on the immediate results of coronary…”
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Calciprotein Particles Induce Cellular Compartment-Specific Proteome Alterations in Human Arterial Endothelial Cells
Published in Journal of cardiovascular development and disease (01-01-2024)“…Calciprotein particles (CPPs) are indispensable scavengers of excessive Ca and PO ions in blood, being internalised and recycled by liver and spleen…”
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Identification of Key Genes and Pathways in Genotoxic Stress Induced Endothelial Dysfunction: Results of Whole Transcriptome Sequencing
Published in Biomedicines (24-08-2022)“…Atherosclerosis is a leading cause of cardiovascular morbidity and mortality worldwide. Endothelial disfunction underlying the atherogenesis can be triggered…”
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14
Albumin-centric calciprotein particles cause pro-inflammatory endothelial activation
Published in Atherosclerosis (01-08-2024)Get full text
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15
Endothelial cells of coronary artery and internal thoracic artery are characterised by molecular heterogeneity and functional synergy
Published in Atherosclerosis (01-08-2024)Get full text
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16
REGULATION OF THE SYSTEMIC INFLAMMATORY RESPONSE IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS
Published in Bajkalʹskij medicinskij žurnal (10-09-2023)“…Introduction. Data on the role of inflammation in the progression and manifestation of multifocal atherosclerosis (MFA) are contradictory. The systemic process…”
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EVALUATION OF THE LOCAL PROFILE OF CYTOKINES EXPRESSED BY NATIVE HEART VALVES OBTAINED FROM PATIENTS WITH ACQUIRED HEART DEFECTS
Published in Bajkalʹskij medicinskij žurnal (10-09-2023)“…Doing. The pathogenesis of acquired heart defects is a complex process involving many different factors. One of the triggers for the development of…”
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CIRCULATION MICRORNA AS A POSSIBLE PREDICTOR OF ANTHRACYCLINE-INDUCED CARDIOTOXICITY
Published in Bajkalʹskij medicinskij žurnal (10-09-2023)“…Introduction. Doxorubicin is an anthracycline antibiotic widely used in the treatment of malignant neoplasms. Anthracyclines have been shown to have an…”
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Inflammatory Response Genes' Polymorphism Associated with Risk of Rheumatic Heart Disease
Published in Journal of personalized medicine (15-07-2024)“…Rheumatic heart disease (RHD) caused by group A streptococcus infection is one of the most important reasons of cardiovascular morbidity and mortality in low-…”
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PREDICTORS OF HOSPITAL COMPLICATIONS AND PROLONGED HOSPITALIZATION IN BYPASS PATIENTS: THE ROLE OF FREE FATTY ACIDS AND INSULIN RESISTANCE INDICES
Published in Bajkalʹskij medicinskij žurnal (10-09-2023)“…Introduction. Often, carbohydrate metabolism disorders (type 2 diabetes mellitus, prediabetes) are detected in patients with severe coronary heart disease who…”
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