Search Results - "Sinisalo, Juha"

Cause-Specific Mortality of Patients With Atrial Septal Defect and Up to 50 Years of Follow-Up by Muroke, Valtteri, Jalanko, Mikko, Haukka, Jari, Sinisalo, Juha

“…Background This study aimed to evaluate the long-term mortality and cause-specific mortality of patients with atrial septal defect (ASD) in a nationwide…”
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Development and validation of a high-throughput LC–MS/MS assay for routine measurement of molecular ceramides by Kauhanen, Dimple, Sysi-Aho, Marko, Koistinen, Kaisa M., Laaksonen, Reijo, Sinisalo, Juha, Ekroos, Kim

“…Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the…”
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A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses by Ripatti, Samuli, Dr, Tikkanen, Emmi, MSc, Orho-Melander, Marju, Prof, Havulinna, Aki S, MSc, Silander, Kaisa, PhD, Sharma, Amitabh, PhD, Guiducci, Candace, BS, Perola, Markus, Prof, Jula, Antti, MD, Sinisalo, Juha, MD, Lokki, Marja-Liisa, PhD, Nieminen, Markku S, Prof, Melander, Olle, MD, Salomaa, Veikko, Prof, Peltonen, Leena, Prof, Kathiresan, Sekar, MD

“…Summary Background Comparison of patients with coronary heart disease and controls in genome-wide association studies has revealed several single nucleotide…”
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Endotoxemia is associated with an adverse metabolic profile by Määttä, Anne-Mari, Salminen, Aino, Pietiäinen, Milla, Leskelä, Jaakko, Palviainen, Teemu, Sattler, Wolfgang, Sinisalo, Juha, Salomaa, Veikko, Kaprio, Jaakko, Pussinen, Pirkko J

“…Our aim was to analyze whether endotoxemia, i.e. translocation of LPS to circulation, is reflected in the serum metabolic profile in a general population and…”
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Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential by Kyttälä, Aija, Moraghebi, Roksana, Valensisi, Cristina, Kettunen, Johannes, Andrus, Colin, Pasumarthy, Kalyan Kumar, Nakanishi, Mahito, Nishimura, Ken, Ohtaka, Manami, Weltner, Jere, Van Handel, Ben, Parkkonen, Olavi, Sinisalo, Juha, Jalanko, Anu, Hawkins, R. David, Woods, Niels-Bjarne, Otonkoski, Timo, Trokovic, Ras

“…Reports on the retention of somatic cell memory in induced pluripotent stem cells (iPSCs) have complicated the selection of the optimal cell type for the…”
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Magnetic resonance imaging safety in patients with abandoned or functioning epicardial pacing leads by Vuorinen, Aino-Maija, Paakkanen, Riitta, Karvonen, Jarkko, Sinisalo, Juha, Holmström, Miia, Kivistö, Sari, Peltonen, Juha I., Kaasalainen, Touko

“…Objectives The European Society of Cardiology Guidelines on cardiac pacing from 2021 allow magnetic resonance imaging (MRI) in patients with cardiac…”
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The Presence of Residual Vascular and Adipose Tissue Inflammation on 18F-FDG PET in Patients with Chronic Coronary Artery Disease by Toivonen, Sini, Lehtinen, Miia, Raivio, Peter, Sinisalo, Juha, Loimaala, Antti, Uusitalo, Valtteri

“…Purpose We evaluated the residual vascular and adipose tissue inflammation in patients with chronic coronary artery disease (CAD) using positron emission…”
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Left ventricular non-compaction as a potential source for cryptogenic ischemic stroke in the young: A case-control study by Pöyhönen, Pauli, Kuusisto, Jouni, Järvinen, Vesa, Pirinen, Jani, Räty, Heli, Lehmonen, Lauri, Paakkanen, Riitta, Martinez-Majander, Nicolas, Putaala, Jukka, Sinisalo, Juha

“…Background Up to 50% of ischemic strokes in the young after thorough diagnostic work-up remain cryptogenic or associated with low-risk sources of…”
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Comparative evaluation of microprobe versus conventional transoesophageal echocardiography for PFO closure guidance by Lanki, Jemina, Tuohinen, Suvi, Simonen, Piia, Jalanko, Mikko, Sinisalo, Juha

“…BackgroundPatent foramen ovale (PFO) closure is traditionally guided by transoesophageal echocardiography (TEE) under general anaesthesia, which prolongs…”
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Exome Sequencing Identifies Susceptibility Loci for Sarcoidosis Prognosis by Lahtela, Elisa, Kankainen, Matti, Sinisalo, Juha, Selroos, Olof, Lokki, Marja-Liisa

“…Many sarcoidosis-associating immunological genes have been shown to be shared between other immune-mediated diseases. In Finnish sarcoidosis patients, good…”
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Safe Deferral of Coronary Computed Tomography Angiography for Patients With a Low Pretest Probability of Coronary Artery Disease in 2019 European Society of Cardiology Guidelines by Varho, Ville, Uusitalo, Valtteri, Vaara, Satu M, Syväranta, Suvi, Rajala, Helena, Sinisalo, Juha

“…Coronary computed tomography angiography is increasingly used as the first-line test for suspected coronary artery disease. Its overuse in a low pretest…”
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Salivary biomarkers of bacterial burden, inflammatory response, and tissue destruction in periodontitis by Salminen, Aino, Gursoy, Ulvi K., Paju, Susanna, Hyvärinen, Kati, Mäntylä, Päivi, Buhlin, Kåre, Könönen, Eija, Nieminen, Markku S., Sorsa, Timo, Sinisalo, Juha, Pussinen, Pirkko J.

“…Aim Chronic periodontitis has an episodic and multifactorial character, with fluctuations in bacterial burden, inflammatory response, and tissue destruction…”
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Data-driven comorbidity analysis of 100 common disorders reveals patient subgroups with differing mortality risks and laboratory correlates by Koskinen, Miika, Salmi, Jani K., Loukola, Anu, Mäkelä, Mika J., Sinisalo, Juha, Carpén, Olli, Renkonen, Risto

“…The populational heterogeneity of a disease, in part due to comorbidity, poses several complexities. Individual comorbidity profiles, on the other hand,…”
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Lipopolysaccharide, a possible molecular mediator between periodontitis and coronary artery disease by Liljestrand, John M., Paju, Susanna, Buhlin, Kåre, Persson, G. Rutger, Sarna, Seppo, Nieminen, Markku S., Sinisalo, Juha, Mäntylä, Päivi, Pussinen, Pirkko J.

“…Aim We aimed to study how lipopolysaccharide (LPS) in saliva and serum associates with each other, periodontal microbial burden, periodontitis and coronary…”
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Relation of Use of Red Blood Cell Transfusion After Acute Coronary Syndrome to Long-Term Mortality by Allonen, Jaakko, Nieminen, Markku S., Hiippala, Seppo, Sinisalo, Juha

“…Registry studies have associated red blood cell (RBC) transfusion with increased in-hospital mortality in patients with acute coronary syndrome (ACS). The…”
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CYP2C19 loss-of-function alleles and use of omeprazole or esomeprazole increase the risk of cardiovascular outcomes in patients using clopidogrel by Ramste, Markus, Ritvos, Markus, Häyrynen, Sergei, Kiiski, Johanna I, Niemi, Mikko, Sinisalo, Juha

“…Our aim was to investigate in a real-life prospective patient cohort how CYP2C19 loss-of-function (LOF) variants and CYP2C19 inhibitor omeprazole or…”
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24-hour ambulatory blood pressure and cryptogenic ischemic stroke in young adults by Tulkki, Lauri, Martinez-Majander, Nicolas, Haapalahti, Petri, Tolppanen, Heli, Sinisalo, Juha, Repo, Olli, Sarkanen, Tomi, Numminen, Heikki, Ryödi, Essi, Ylikotila, Pauli, Roine, Risto O., Lautamäki, Riikka, Saraste, Antti, Miettinen, Tuuli, Autere, Jaana, Jäkälä, Pekka, Hedman, Marja, Huhtakangas, Juha, Junttola, Ulla, Putaala, Jukka, Pirinen, Jani

“…In young patients, up to 40% of ischemic strokes remain cryptogenic despite modern-day diagnostic work-up. There are limited data on blood pressure (BP)…”
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Follow-up of intramyocardial bone marrow mononuclear cell transplantation beyond 10 years by Mulari, Severi, Kesävuori, Risto, Stewart, Juhani A., Karjalainen, Pasi, Holmström, Miia, Lehtinen, Miia, Peltonen, Juha, Laine, Mika, Sinisalo, Juha, Juvonen, Tatu, Kupari, Markku, Harjula, Ari, Pätilä, Tommi, Kivistö, Sari, Kankuri, Esko, Vento, Antti

“…Bone marrow mononuclear cells (BMMCs) have been evaluated for their ability to improve cardiac repair and benefit patients with severe ischemic heart disease…”
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Left Atrial Dynamics Is Altered in Young Adults With Cryptogenic Ischemic Stroke: A Case-Control Study Utilizing Advanced Echocardiography by Pirinen, Jani, Järvinen, Vesa, Martinez-Majander, Nicolas, Sinisalo, Juha, Pöyhönen, Pauli, Putaala, Jukka

“…Background Ischemic stroke in young individuals often remains cryptogenic. Some of these strokes likely originate from the heart, and atrial fibrosis might be…”
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Acquired left ventricular-right atrium shunts by Sinisalo, Juha P., Sreeram, Narayanswami, Jokinen, Eero, Qureshi, Shakeel A.

“…Summary Left ventricular to right atrial (LV-RA) shunt is an unusual type of ventricular septal defect (VSD). This article concentrates on acquired LV-RA…”
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