Search Results - "Sinha, U"

Chromatin-modifying enzymes as modulators of reprogramming by Onder, Tamer T., Kara, Nergis, Cherry, Anne, Sinha, Amit U., Zhu, Nan, Bernt, Kathrin M., Cahan, Patrick, Mancarci, B. Ogan, Unternaehrer, Juli, Gupta, Piyush B., Lander, Eric S., Armstrong, Scott A., Daley, George Q.

“…Inhibition of DOT1L, the H3K79 histone methyltransferase, increases cell reprogramming and substituted for KLF4 and c-Myc, showing that chromatin-modifying…”
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Polycomb repressive complex 2 is required for MLL-AF9 leukemia by Neff, Tobias, Sinha, Amit U, Kluk, Michael J, Zhu, Nan, Khattab, Mohamed H, Stein, Lauren, Xie, Huafeng, Orkin, Stuart H, Armstrong, Scott A

“…A growing body of data suggests the importance of epigenetic mechanisms in cancer. Polycomb repressive complex 2 (PRC2) has been implicated in self-renewal and…”
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Control strategies and performance analysis of doubly fed induction generator for grid-connected wind energy conversion system by Vardhan, Aanchal Singh S., Sinha, U. K.

“…This paper presents the control strategies and performance analysis of doubly fed induction generator (DFIG) for grid-connected wind energy conversion system…”
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Characterization of Mechanisms and Processes Controlling Groundwater Recharge and its Quality in Drought-Prone Region of Central India (Buldhana, Maharashtra) Using Isotope Hydrochemical and End-Member Mixing Modeling by Keesari, Tirumalesh, Roy, Annadasankar, Mohokar, Hemant, Pant, Diksha, Sinha, U. K.

“…A thorough study on understanding of groundwater recharge sources and mechanisms was attempted by integrating the hydrogeological, geochemical and isotopic…”
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AF10 Regulates Progressive H3K79 Methylation and HOX Gene Expression in Diverse AML Subtypes by Deshpande, Aniruddha J., Deshpande, Anagha, Sinha, Amit U., Chen, Liying, Chang, Jenny, Cihan, Ali, Fazio, Maurizio, Chen, Chun-wei, Zhu, Nan, Koche, Richard, Dzhekieva, Liuda, Ibáñez, Gloria, Dias, Stuart, Banka, Deepti, Krivtsov, Andrei, Luo, Minkui, Roeder, Robert G., Bradner, James E., Bernt, Kathrin M., Armstrong, Scott A.

“…Homeotic (HOX) genes are dysregulated in multiple malignancies, including several AML subtypes. We demonstrate that H3K79 dimethylation (H3K79me2) is converted…”
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Study on uranium contamination in groundwater of Faridkot and Muktsar districts of Punjab using stable isotopes of water by Pant, Diksha, Keesari, Tirumalesh, Sharma, Diana, Rishi, Madhuri, Singh, Gagandeep, Jaryal, Ajay, Sinha, U. K., Dash, A., Tripathi, R. M.

“…Environmental isotopic study has been conducted in Faridkot and Muktsar districts of Punjab to assess the uranium contamination as well as to determine the…”
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Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l by Deshpande, Aniruddha J., Chen, Liying, Fazio, Maurizio, Sinha, Amit U., Bernt, Kathrin M., Banka, Deepti, Dias, Stuart, Chang, Jenny, Olhava, Edward J., Daigle, Scott R., Richon, Victoria M., Pollock, Roy M., Armstrong, Scott A.

“…The t(6;11)(q27;q23) is a recurrent chromosomal rearrangement that encodes the MLLAF6 fusion oncoprotein and is observed in patients with diverse hematologic…”
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Study on groundwater quality in parts of Rajasthan with special reference to uranium contamination by Pant, Diksha, Keesari, Tirumalesh, Roy, A., Sinha, U. K., Singh, Manveer, Jain, S. K., Tripathi, R. M.

“…Issues of declining water levels and groundwater contamination are reported in parts of Rajasthan in recent times. One of the major contaminants present in the…”
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Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains by Trowbridge, Jennifer J, Sinha, Amit U, Zhu, Nan, Li, Mingjie, Armstrong, Scott A, Orkin, Stuart H

“…Epigenetic mechanisms regulating leukemia stem cells (LSCs) are an attractive target for therapy of blood cancers. Here, we report that conditional knockout of…”
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Efficient Multilevel Brain Tumor Segmentation With Integrated Bayesian Model Classification by Corso, J.J., Sharon, E., Dube, S., El-Saden, S., Sinha, U., Yuille, A.

“…We present a new method for automatic segmentation of heterogeneous image data that takes a step toward bridging the gap between bottom-up affinity-based…”
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Distribution of environmental tritium in rivers, groundwater, mine water and precipitation in Goa, India by Ansari, Md. Arzoo, Mohokar, H.V., Deodhar, Archana, Jacob, Noble, Sinha, U.K.

“…Tritium concentration in rivers, groundwater, precipitation and mine pits water, all over Goa state was characterized to find out spatial and temporal…”
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MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C by Zhu, Nan, Chen, Mo, Eng, Rowena, DeJong, Joshua, Sinha, Amit U, Rahnamay, Noushin F, Koche, Richard, Al-Shahrour, Fatima, Minehart, Janna C, Chen, Chun-Wei, Deshpande, Aniruddha J, Xu, Haiming, Chu, S Haihua, Ebert, Benjamin L, Roeder, Robert G, Armstrong, Scott A

“…Self-renewal is a hallmark of both hematopoietic stem cells (HSCs) and leukemia stem cells (LSCs); therefore, the identification of mechanisms that are…”
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Shock formation in magnetised electron-positron plasmas: mechanism and timing by Novo, A Stockem, Bret, A, Sinha, U

“…The shock formation process in electron-positron pair plasmas is investigated in the presence of an ambient perpendicular magnetic field. In initially…”
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H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias by Krivtsov, Andrei V., Feng, Zhaohui, Lemieux, Madeleine E., Faber, Joerg, Vempati, Sridhar, Sinha, Amit U., Xia, Xiaobo, Jesneck, Jonathan, Bracken, Adrian P., Silverman, Lewis B., Kutok, Jeffery L., Kung, Andrew L., Armstrong, Scott A.

“…We created a mouse model wherein conditional expression of an Mll-AF4 fusion oncogene induces B precursor acute lymphoblastic (ALL) or acute myeloid leukemias…”
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mTOR Complex 1 Plays Critical Roles in Hematopoiesis and Pten-Loss-Evoked Leukemogenesis by Kalaitzidis, Demetrios, Sykes, Stephen M., Wang, Zhu, Punt, Natalie, Tang, Yuefeng, Ragu, Christine, Sinha, Amit U., Lane, Steven W., Souza, Amanda L., Clish, Clary B., Anastasiou, Dimitrios, Gilliland, D. Gary, Scadden, David T., Guertin, David A., Armstrong, Scott A.

“…The mechanistic target of rapamycin (mTOR) pathway serves as a key sensor of cellular-energetic state and functions to maintain tissue homeostasis…”
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Isotope-geochemical assessment of thermal waters and their impact on surrounding potable water resources in the Tapi valley geothermal area, Maharashtra, India by Chatterjee, Sitangshu, Biswal, B. P., Sinha, U. K., Patbhaje, S. D.

“…Geochemical and isotopic investigations were carried out in the Tapi Valley geothermal area in India to determine the principal factors that are responsible…”
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Recent advances in breast MRI and MRS by Sinha, S., Sinha, U.

“…Breast MRI is an area of intense research and is fast becoming an important tool for the diagnosis of breast cancer. This review covers recent advances in…”
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Cinteny: flexible analysis and visualization of synteny and genome rearrangements in multiple organisms by Sinha, Amit U, Meller, Jaroslaw

“…Identifying syntenic regions, i.e., blocks of genes or other markers with evolutionary conserved order, and quantifying evolutionary relatedness between…”
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Cell of origin determines clinically relevant subtypes of MLL-rearranged AML by Krivtsov, A V, Figueroa, M E, Sinha, A U, Stubbs, M C, Feng, Z, Valk, P J M, Delwel, R, Döhner, K, Bullinger, L, Kung, A L, Melnick, A M, Armstrong, S A

“…Mixed lineage leukemia (MLL)-fusion proteins can induce acute myeloid leukemias (AMLs) from either hematopoietic stem cells (HSCs) or granulocyte–macrophage…”
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Appraising the factors favouring uranium mobilization and associated health risk assessment in groundwaters of north-western India by Sharma, Diana A., Keesari, Tirumalesh, Pant, Diksha, Rishi, Madhuri S., Sangwan, Priyanka, Thakur, Nandini, Sinha, U.K.

“…An attempt has been made in this study to evaluate the factors favoring the uranium mobilization into the groundwater of Northwest India using uranium isotope…”
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