Search Results - "Sinha, Sunita"

p32 promotes melanoma progression and metastasis by targeting EMT markers, Akt/PKB pathway, and tumor microenvironment by Sinha, Sunita, Singh, Satyendra Kumar, Jangde, Nitish, Ray, Rashmi, Rai, Vivek

“…Melanoma originates from melanin-producing cells called melanocytes. Melanoma poses a great risk because of its rapid ability to spread and invade new organs…”
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Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance by Skovsø, Søs, Panzhinskiy, Evgeniy, Kolic, Jelena, Cen, Haoning Howard, Dionne, Derek A., Dai, Xiao-Qing, Sharma, Rohit B., Elghazi, Lynda, Ellis, Cara E., Faulkner, Katharine, Marcil, Stephanie A. M., Overby, Peter, Noursadeghi, Nilou, Hutchinson, Daria, Hu, Xiaoke, Li, Hong, Modi, Honey, Wildi, Jennifer S., Botezelli, J. Diego, Noh, Hye Lim, Suk, Sujin, Gablaski, Brian, Bautista, Austin, Kim, Ryekjang, Cras-Méneur, Corentin, Flibotte, Stephane, Sinha, Sunita, Luciani, Dan S., Nislow, Corey, Rideout, Elizabeth J., Cytrynbaum, Eric N., Kim, Jason K., Bernal-Mizrachi, Ernesto, Alonso, Laura C., MacDonald, Patrick E., Johnson, James D.

“…Insulin receptor (Insr) protein is present at higher levels in pancreatic β-cells than in most other tissues, but the consequences of β-cell insulin resistance…”
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Reduced Circulating Insulin Enhances Insulin Sensitivity in Old Mice and Extends Lifespan by Templeman, Nicole M., Flibotte, Stephane, Chik, Jenny H.L., Sinha, Sunita, Lim, Gareth E., Foster, Leonard J., Nislow, Corey, Johnson, James D.

“…The causal relationships between insulin levels, insulin resistance, and longevity are not fully elucidated. Genetic downregulation of insulin/insulin-like…”
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MYH9 suppresses melanoma tumorigenesis, metastasis and regulates tumor microenvironment by Singh, Satyendra Kumar, Sinha, Sunita, Padhan, Jyotirmayee, Jangde, Nitish, Ray, Rashmi, Rai, Vivek

“…Non-muscle myosin IIA heavy chain (MYH9) has been implicated in many physiological and pathological functions including cell adhesion, polarity, motility to…”
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Absence of Detectable Arsenate in DNA from Arsenate-Grown GFAJ-1 Cells by Reaves, Marshall Louis, Sinha, Sunita, Rabinowitz, Joshua D., Kruglyak, Leonid, Redfield, Rosemary J.

“…A strain of Halomonas bacteria, GFAJ-1, has been claimed to be able to use arsenate as a nutrient when phosphate is limiting and to specifically incorporate…”
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Natural DNA uptake by Escherichia coli by Sinha, Sunita, Redfield, Rosemary J

“…Escherichia coli has homologues of the competence genes other species use for DNA uptake and processing, but natural competence and transformation have never…”
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Characterization of the gut microbiome in a porcine model of thoracic spinal cord injury by Doelman, Adam, Tigchelaar, Seth, McConeghy, Brian, Sinha, Sunita, Keung, Martin S, Manouchehri, Neda, Webster, Megan, Fisk, Shera, Morrison, Charlotte, Streijger, Femke, Nislow, Corey, Kwon, Brian K

“…The gut microbiome is a diverse network of bacteria which inhabit our digestive tract and is crucial for efficient cellular metabolism, nutrient absorption,…”
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Lysophosphatidic acid-RAGE axis promotes lung and mammary oncogenesis via protein kinase B and regulating tumor microenvironment by Ray, Rashmi, Jangde, Nitish, Singh, Satyendra Kumar, Sinha, Sunita, Rai, Vivek

“…Receptor for advanced glycation end products (RAGE) is a multi-ligand transmembrane receptor of the immunoglobulin superfamily. Lysophosphatidic acid (LPA) is…”
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Serum MicroRNAs Reflect Injury Severity in a Large Animal Model of Thoracic Spinal Cord Injury by Tigchelaar, Seth, Streijger, Femke, Sinha, Sunita, Flibotte, Stephane, Manouchehri, Neda, So, Kitty, Shortt, Katelyn, Okon, Elena, Rizzuto, Michael A., Malenica, Ivana, Courtright-Lim, Amanda, Eisen, Andrew, Keuren-Jensen, Kendall Van, Nislow, Corey, Kwon, Brian K.

“…Therapeutic development for spinal cord injury is hindered by the difficulty in conducting clinical trials, which to date have relied solely on functional…”
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Seventeen Sxy-Dependent Cyclic AMP Receptor Protein Site-Regulated Genes Are Needed for Natural Transformation in Haemophilus influenzae by Sinha, Sunita, Mell, Joshua C, Redfield, Rosemary J

“…Natural competence is the ability of bacteria to actively take up extracellular DNA. This DNA can recombine with the host chromosome, transforming the host…”
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Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids by Mor, Visesato, Rella, Antonella, Farnoud, Amir M, Singh, Ashutosh, Munshi, Mansa, Bryan, Arielle, Naseem, Shamoon, Konopka, James B, Ojima, Iwao, Bullesbach, Erika, Ashbaugh, Alan, Linke, Michael J, Cushion, Melanie, Collins, Margaret, Ananthula, Hari Krishna, Sallans, Larry, Desai, Pankaj B, Wiederhold, Nathan P, Fothergill, Annette W, Kirkpatrick, William R, Patterson, Thomas, Wong, Lai Hong, Sinha, Sunita, Giaever, Guri, Nislow, Corey, Flaherty, Patrick, Pan, Xuewen, Cesar, Gabriele Vargas, de Melo Tavares, Patricia, Frases, Susana, Miranda, Kildare, Rodrigues, Marcio L, Luberto, Chiara, Nimrichter, Leonardo, Del Poeta, Maurizio

“…Recent estimates suggest that >300 million people are afflicted by serious fungal infections worldwide. Current antifungal drugs are static and toxic and/or…”
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Correction to: Characterization of the gut microbiome in a porcine model of thoracic spinal cord injury by Doelman, Adam, Tigchelaar, Seth, McConeghy, Brian, Sinha, Sunita, Keung, Martin S, Manouchehri, Neda, Webster, Megan, Fisk, Shera, Morrison, Charlotte, Streijger, Femke, Nislow, Corey, Kwon, Brian K

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Anti-proliferative and anti-migratory effects of flower-like bimetallic (Au@Pt) nanoparticles by Princely, Sebastian Xavier, Puja, Patel, Vinita, Manimaran Nadar, Devan, Umapathy, Velangani, Antony Joseph, Sunita, Sinha, Yuvakkumar, Rathinam, Velmurugan, Palanivelu, Ravi, Arumugam Veera, Govarthanan, Muthusamy, Kumar, Ponnuchamy

“…[Display omitted] •Flower-like bimetallic (Au@Pt) nanoparticles were synthesized using Carica papaya leaf extract.•Optical, structural, and functional…”
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14-3-3ζ coordinates adipogenesis of visceral fat by Lim, Gareth E., Albrecht, Tobias, Piske, Micah, Sarai, Karnjit, Lee, Jason T. C, Ramshaw, Hayley S., Sinha, Sunita, Guthridge, Mark A., Acker-Palmer, Amparo, Lopez, Angel F., Clee, Susanne M., Nislow, Corey, Johnson, James D.

“…The proteins that coordinate complex adipogenic transcriptional networks are poorly understood. 14-3-3ζ is a molecular adaptor protein that regulates insulin…”
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A competence-regulated toxin-antitoxin system in Haemophilus influenzae by Findlay Black, Hailey, Mastromatteo, Scott, Sinha, Sunita, Ehrlich, Rachel L, Nislow, Corey, Chang Mell, Joshua, Redfield, Rosemary J

“…Natural competence allows bacteria to respond to environmental and nutritional cues by taking up free DNA from their surroundings, thus gaining both nutrients…”
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Microbial dysbiosis and the host airway epithelial response: insights into HIV-associated COPD using multi'omics profiling by Jude, Marcia Smiti, Yang, Chen Xi, Filho, Fernando Studart Leitao, Hernandez Cordero, Ana I, Yang, Julia, Shaipanich, Tawimas, Li, Xuan, Lin, David, MacIsaac, Julie, Kobor, Michael S, Sinha, Sunita, Nislow, Corey, Singh, Amrit, Lam, Wan, Lam, Stephen, Guillemi, Silvia, Harris, Marianne, Montaner, Julio, Ng, Raymond T, Carlsten, Christopher, Paul Man, S F, Sin, Don D, Leung, Janice M

“…People living with HIV (PLWH) are at increased risk of developing Chronic Obstructive Pulmonary Disease (COPD) independent of cigarette smoking. We…”
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Reverse Chemical Genetics: Comprehensive Fitness Profiling Reveals the Spectrum of Drug Target Interactions by Wong, Lai H, Sinha, Sunita, Bergeron, Julien R, Mellor, Joseph C, Giaever, Guri, Flaherty, Patrick, Nislow, Corey

“…The emergence and prevalence of drug resistance demands streamlined strategies to identify drug resistant variants in a fast, systematic and cost-effective…”
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Seven Years at High Salinity—Experimental Evolution of the Extremely Halotolerant Black Yeast Hortaea werneckii by Gostinčar, Cene, Stajich, Jason E., Kejžar, Anja, Sinha, Sunita, Nislow, Corey, Lenassi, Metka, Gunde-Cimerman, Nina

“…The experimental evolution of microorganisms exposed to extreme conditions can provide insight into cellular adaptation to stress. Typically, stress-sensitive…”
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Insight into the Recent Genome Duplication of the Halophilic Yeast Hortaea werneckii : Combining an Improved Genome with Gene Expression and Chromatin Structure by Sinha, Sunita, Flibotte, Stephane, Neira, Mauricio, Formby, Sean, Plemenitaš, Ana, Cimerman, Nina Gunde, Lenassi, Metka, Gostinčar, Cene, Stajich, Jason E, Nislow, Corey

“…Extremophilic organisms demonstrate the flexibility and adaptability of basic biological processes by highlighting how cell physiology adapts to environmental…”
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Decreased microbiome diversity in the HIV small airway epithelium by Xu, Stella, Tsai, Amy, Sze, Marc A, Vucic, Emily A, Shaipanich, Tawimas, Harris, Marianne, Guillemi, Silvia, Yang, Julia, Sinha, Sunita, Nislow, Corey, Montaner, Julio, Lam, Wan, Lam, Stephen, Sin, Don D, Paul Man, S F, Leung, Janice M

“…Persons living with human immunodeficiency virus (PLWH) face an increased burden of chronic obstructive pulmonary disease (COPD). Repeated pulmonary…”
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