Search Results - "Sinha, Roshani"

Novel Humanized Loss-of-Function NF1 Mouse Model of Juvenile Myelomonocytic Leukemia by Sinha, Roshani, Patil, Rachana, Romano, Rosa, Lee, Esmond, Yao, Zhenyu, Liu, Y. Lucy, Porteus, Matthew H., Bertaina, Alice

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Aberrant Histone Landscape in Juvenile Myelomonocytic Leukemia by Sinha, Roshani, Dvorak, Mai, Niemeyer, Charlotte M., Sakamoto, Kathleen M., Patil, Rachana, Utz, Paul J, Liu, Y. Lucy, Kuo, Alex, Bertaina, Alice

“…Juvenile myelomonocytic leukemia (JMML) is a deadly pediatric cancer characterized by excessive accumulation of monocytes/macrophages with myelodysplastic…”
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Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation by Porcheri, Cristina, Golan, Ohad, Calero‐Nieto, Fernando J, Thambyrajah, Roshana, Ruiz‐Herguido, Cristina, Wang, Xiaonan, Catto, Francesca, Guillén, Yolanda, Sinha, Roshani, González, Jessica, Kinston, Sarah J, Mariani, Samanta A, Maglitto, Antonio, Vink, Chris S, Dzierzak, Elaine, Charbord, Pierre, Göttgens, Bertie, Espinosa, Lluis, Sprinzak, David, Bigas, Anna

“…Hematopoietic stem cells (HSCs) develop from the hemogenic endothelium in cluster structures that protrude into the embryonic aortic lumen. Although much is…”
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Development of embryonic and adult leukemia mouse models driven by MLL-ENL translocation by Sinha, Roshani, Porcheri, Cristina, d'Altri, Teresa, González, Jessica, Ruiz-Herguido, Cristina, Rabbitts, Terry, Espinosa, Lluis, Bigas, Anna

“…•The MLL-ENL translocation drives acute myeloid leukemia in mice.•An embryonic leukemia model was developed by inducing MLL-ENL translocation in utero (at…”
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Visualizing the hematopoietic emergence in the mouse embryo by Porcheri, Cristina, Sinha, Roshani, Espinosa, Lluis, Bigas, Anna

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Epigenetic Profiling of IPTPN11/I Mutant JMML Hematopoietic Stem and Progenitor Cells Reveals an Aberrant Histone Landscape by Sinha, Roshani, Dvorak, Mai, Ganesan, Ananthakrishnan, Kalesinskas, Larry, Niemeyer, Charlotte M, Flotho, Christian, Sakamoto, Kathleen M, Lacayo, Norman, Patil, Rachana Vinay, Perriman, Rhonda, Cepika, Alma-Ma, Liu, Yunying Lucy, Kuo, Alex, Utz, Paul J, Khatri, Purvesh, Bertaina, Alice

“…Juvenile myelomonocytic leukemia (JMML) is a deadly pediatric leukemia with limited treatment options and poor clinical outcomes. Effective targeted treatment…”
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Understanding the development of MLL rearranged leukemias by Sinha, Roshani, Porcheri, Cristina, Teresa d'Altri, Espinosa, Lluis, Salvans, Anna Bigas

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Epigenetic Profiling of PTPN11 Mutant JMML Hematopoietic Stem and Progenitor Cells Reveals an Aberrant Histone Landscape by Sinha, Roshani, Dvorak, Mai, Ganesan, Ananthakrishnan, Kalesinskas, Larry, Niemeyer, Charlotte M, Flotho, Christian, Sakamoto, Kathleen M, Lacayo, Norman, Patil, Rachana Vinay, Perriman, Rhonda, Cepika, Alma-Martina, Liu, Yunying Lucy, Kuo, Alex, Utz, Paul J, Khatri, Purvesh, Bertaina, Alice

“…Juvenile myelomonocytic leukemia (JMML) is a deadly pediatric leukemia driven by pathway mutations, of which >35% are gain-of-function in . Although DNA…”
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301 - G-CSF +/- Plerixafor PBSC Mobilization and αβ t-Cell/CD19 B-Cell Depletion Impact Donor T-Cell Gene Expression Profiles by Montiel-Esparza, Raul, Sinha, Roshani, Barbarito, Giulia, Patil, Rachana, Saini, Gopin, Shyr, David C., Davies, Kimberly, Ji, Xuhuai, Yao, Zhenyu, Parkman, Robertson, Bertaina, Alice

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G-CSF +/- Plerixafor PBSC Mobilization and αβ t-Cell/CD19 B-Cell Depletion Impact Donor T-Cell Gene Expression Profiles by Montiel-Esparza, Raul, Sinha, Roshani, Barbarito, Giulia, Patil, Rachana, Saini, Gopin, Shyr, David C., Davies, Kimberly, Ji, Xuhuai, Yao, Zhenyu, Parkman, Robertson, Bertaina, Alice

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454 - Kinetics of Gamma Delta T-Cell Immune Reconstitution: An Immunophenotypic and Molecular Analysis by Barbarito, Giulia, Louis, David M, Saini, Gopin, Ji, Xuhuai, Kristovich, Karen, Sinha, Roshani, Patil, Rachana, Batish, Arpit, Parkman, Robertson, Bertaina, Alice

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Kinetics of Gamma Delta T-Cell Immune Reconstitution: An Immunophenotypic and Molecular Analysis by Barbarito, Giulia, Louis, David M, Saini, Gopin, Ji, Xuhuai, Kristovich, Karen, Sinha, Roshani, Patil, Rachana, Batish, Arpit, Parkman, Robertson, Bertaina, Alice

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