Search Results - "Sinha, Chandrima"

Amberlite–IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: Antibacterial and antifungal evaluation of the products by Hazra, Abhijit, Mondal, Shyamal, Maity, Arindam, Naskar, Subhendu, Saha, Pritam, Paira, Rupankar, Sahu, Krishnendu B., Paira, Priyankar, Ghosh, Soma, Sinha, Chandrima, Samanta, Amalesh, Banerjee, Sukdeb, Mondal, Nirup B.

“…A number of indolizines and pyrrolo[1,2-a]quinolines/isoquinolines were prepared from phenacyl pyridinium, quinolinium and isoquinolinium salts derived fromthe…”
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An unexpected protein interaction promotes drug resistance in leukemia by Pitre, Aaron, Ge, Yubin, Lin, Wenwei, Wang, Yao, Fukuda, Yu, Temirov, Jamshid, Phillips, Aaron H., Peters, Jennifer L., Fan, Yiping, Ma, Jing, Nourse, Amanda, Sinha, Chandrima, Lin, Hai, Kriwacki, Richard, Downing, James R., Gruber, Tanja A., Centonze, Victoria E., Naren, Anjaparavanda P., Chen, Taosheng, Schuetz, John D.

“…The overall survival of patients with acute myeloid leukemia (AML) is poor and identification of new disease-related therapeutic targets remains a major goal…”
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Compartmentalization of cyclic nucleotide signaling: a question of when, where, and why? by Arora, Kavisha, Sinha, Chandrima, Zhang, Weiqiang, Ren, Aixia, Moon, Chang Suk, Yarlagadda, Sunitha, Naren, Anjaparavanda P.

“…Preciseness of cellular behavior depends upon how an extracellular cue mobilizes a correct orchestra of cellular messengers and effector proteins spatially and…”
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Compartmentalized Accumulation of cAMP near Complexes of Multidrug Resistance Protein 4 (MRP4) and Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Contributes to Drug-induced Diarrhea by Moon, Changsuk, Zhang, Weiqiang, Ren, Aixia, Arora, Kavisha, Sinha, Chandrima, Yarlagadda, Sunitha, Woodrooffe, Koryse, Schuetz, John D., Valasani, Koteswara Rao, de Jonge, Hugo R., Shanmukhappa, Shiva Kumar, Shata, Mohamed Tarek M., Buddington, Randal K., Parthasarathi, Kaushik, Naren, Anjaparavanda P.

“…Diarrhea is one of the most common adverse side effects observed in ∼7% of individuals consuming Food and Drug Administration (FDA)-approved drugs. The…”
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Methods to Study Mrp4-containing Macromolecular Complexes in the Regulation of Fibroblast Migration by Sinha, Chandrima, Arora, Kavisha, Naren, Anjaparavanda P

“…Multidrug resistance protein 4 (MRP4) is a member of the ATP-binding cassette family of membrane transporters and is an endogenous efflux transporter of cyclic…”
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An investigation on in vitro and in vivo antimicrobial properties of the antidepressant: amitriptyline hydrochloride by Mandal, Anurup(Jadavpur University Department of Pharmaceutical Technology Division of Microbiology), Sinha, Chandrima(Jadavpur University Department of Pharmaceutical Technology Division of Microbiology), Jena, Aditya Kumar(Jadavpur University Department of Pharmaceutical Technology Division of Microbiology), Ghosh, Soma(Jadavpur University Department of Pharmaceutical Technology Division of Microbiology), Samanta, Amalesh(Jadavpur University Department of Pharmaceutical Technology Division of Microbiology)

“…The antidepressant drug amitriptyline hydrochloride was obtained in a dry powder form and was screened against 253 strains of bacteria which included 72 Gram…”
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CD62L and TCR αβ Depletion of Donors in a Double Haploidentical BMT Model Leads to Improved Donor Engraftment by Seth, Aman, MS, Sinha, Chandrima, PhD, Kahali, Bhaskar, PhD, Leung, Wing H., MD, PhD, Cunningham, Lea, MD

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Modulation of NKG2D Ligands Expression in Acute Myeloid Leukemia by Sinha, Chandrima, PhD, Ju, Bensheng, PhD, Ong, Su Sien, PhD, Goktug, Asli, MS, Lin, Wenwei, PhD, Seth, Aman, MS, Kahali, Bhaskar, PhD, Chen, Taosheng, PhD, Leung, Wing H., MD, PhD, Cunningham, Lea, MD

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An overview of the potential strategies for NK cell-based immunotherapy for acute myeloid leukemia by Sinha, Chandrima, Cunningham, Lea C.

“…Patients with acute myeloid leukemia (AML) have relatively low survival rates compared to patients with other pediatric cancers. Relapse is frequent with…”
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SWI/SNF Chromatin Remodeling Complex Regulates the Expression of PD-L1 in a Spatio-Temporal Manner in Acute Lymphoblastic Leukemia (ALL) in Vitro by Kahali, Bhaskar, Sinha, Chandrima, Ritter, Abby, Cunningham, Lea C.

“…Epigenetic changes and interactions between different cells within the tumor microenvironment are critical for the maintenance and progression of cancer. The…”
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Core Binding Factor Acute Myeloid Leukemia: New Prognostic Categories and Therapeutic Opportunities by Sinha, Chandrima, Cunningham, Lea C, Liu, Paul P

“…Core binding factor (CBF) is a heterodimeric protein complex involved in the transcriptional regulation of normal hematopoiesis. Mutations in CBF-encoding…”
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An Evaluation of the Cytotoxic Effect of the Natural Product Aaptamine Against t(4;11) Leukemias by Sinha, Chandrima, Bowling, John, Seth, Aman, Ju, Bensheng, Kahali, Bhaskar, Hamann, Mark, Cunningham, Lea C.

“…The marine environment has been shown to be a rich source of pharmacologically-active secondary metabolites. Three marine- compounds have FDA approval for…”
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Methods to Study Mrp4-containing Macromolecular Complexes in the Regulation of Fibroblast Migration by Sinha, Chandrima, Arora, Kavisha, Naren, Anjaparavanda P.

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Stabilizing Rescued Surface-Localized ΔF508 CFTR by Potentiation of Its Interaction with Na+/H+ Exchanger Regulatory Factor 1 by Arora, Kavisha, Moon, Changsuk, Zhang, Weiqiang, Yarlagadda, Sunitha, Penmatsa, Himabindu, Ren, Aixia, Sinha, Chandrima, Naren, Anjaparavanda P

“…Cystic fibrosis (CF) is a recessive genetic disease caused by mutations in CFTR, a plasma-membrane-localized anion channel. The most common mutation in CFTR,…”
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Core binding factor AML: New prognostic categories and therapeutic opportunities by Sinha, Chandrima, Cunningham, Lea C., Liu, Paul P.

“…Core binding factor (CBF) is a heterodimeric protein complex involved in the transcriptional regulation of normal hematopoiesis. Mutations in CBF-encoding…”
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Tu1734 Inhibition of MRP4 Enhances the Wound Repair Process by Sinha, Chandrima, Naren, Anjaparavanda P

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Förster Resonance Energy Transfer — An approach to visualize the spatiotemporal regulation of macromolecular complex formation and compartmentalized cell signaling by Sinha, Chandrima, Arora, Kavisha, Moon, Chang Suk, Yarlagadda, Sunitha, Woodrooffe, Koryse, Naren, Anjaparavanda P.

“…Signaling messengers and effector proteins provide an orchestrated molecular machinery to relay extracellular signals to the inside of cells and thereby…”
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Multi-drug Resistance Protein 4 (MRP4)-mediated Regulation of Fibroblast Cell Migration Reflects a Dichotomous Role of Intracellular Cyclic Nucleotides by Sinha, Chandrima, Ren, Aixia, Arora, Kavisha, Moon, Chang-Suk, Yarlagadda, Sunitha, Zhang, Weiqiang, Cheepala, Satish B., Schuetz, John D., Naren, Anjaparavanda P.

“…It has long been known that cyclic nucleotides and cyclic nucleotide-dependent signaling molecules control cell migration. However, the concept that it is not…”
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Altered cGMP Dynamics at the Plasma Membrane Contribute to Diarrhea in Ulcerative Colitis by Arora, Kavisha, Sinha, Chandrima, Zhang, Weiqiang, Moon, Chang Suk, Ren, Aixia, Yarlagadda, Sunitha, Dostmann, Wolfgang R, Adebiyi, Adebowale, Haberman, Yael, Denson, Lee A, Wang, Xusheng, Naren, Anjaparavanda P

“…Ulcerative colitis (UC) belongs to inflammatory bowel disorders, a group of gastrointestinal disorders that can produce serious recurring diarrhea in affected…”
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Capturing the Direct Binding of CFTR Correctors to CFTR by Using Click Chemistry by Sinha, Chandrima, Zhang, Weiqiang, Moon, Chang Suk, Actis, Marcelo, Yarlagadda, Sunitha, Arora, Kavisha, Woodroofe, Koryse, Clancy, John P., Lin, Songbai, Ziady, Assem G., Frizzell, Raymond, Fujii, Naoaki, Naren, Anjaparavanda P.

“…Cystic fibrosis (CF) is a lethal genetic disease caused by the loss or dysfunction of the CF transmembrane conductance regulator (CFTR) channel. F508del is the…”
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