Search Results - "Sinha, Arghyotri"

Abstract LB-061: CRD5500: A versatile small molecule STING agonist amenable to bioconjugation as an ADC by Banerjee, Monali, Basu, Sourav, Middya, Sandip, Shrivastava, Ritesh, Ghosh, Rajib, Pryde, David C., Yadav, Dharmendra, Bhattacharya, Gopal, Soram, Thanilsana, Puniya, Kavita, Raina, Ritika, Kadam, Vijay, Garai, Sujay, Sharma, Priti, Singh, Anuj, Shinde, Vaibhav, Rawat, Nidhi, Middya, Anindita, Sinha, Arghyotri, Chandel, Sunita, Narisipuram, Ganesh, Chatterjee, Abhisek, Mane, Nagaswamy, Surya, Arjun

“…BACKGROUND Innate immune signaling mediated through STING (Stimulator of Interferon Genes) generates a Type I interferon (Type 1 IFN) signal that increases T…”
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Abstract 3510: Small molecule ACSS2 inhibitors target acetate metabolizing tumor cells in hypoxic conditions by Banerjee, Monali, Basu, Sourav, Chakraborty, Debjani, Shrivastava, Ritesh, Middya, Sandip, Ghosh, Rajib, Yadav, Dharmendra, Sinha, Arghyotri, Das, Avratanu, Pandit, Navin, Naiya, Mohinder, Debnath, Sabyasachi, Dey, Sangeeta, Dasgupta, Debottam, Das, Nirmal, Singh, Anuj, Sarkar, Dipayan, Sarkar, Sukanya, Narasipuram, Ganesh, Mane, Nagaswami, Singhal, Nicky, Rawat, Nidhi, Middya, Anindita, Surya, Arjun

“…BACKGROUND Tumors such as glioblastoma proliferating under hypoxic, hypoglycemic and hypolipidemic conditions derive almost half of their nutritional…”
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Abstract LB163: Discovery and characterization of QTX3544, a potent, selective, and orally bioavailable allosteric G12V preferring multi KRAS inhibitor by Zhang, Yang W., Vo, Elizabeth Donohue, Gan, Pei, Rominger, Dave, Silva, Jillian M., Zhang, Yang J., Pan, Christopher, Lee, Greg, Micozzi, John M., Reid, Ben, McDonough, Brooke, Sinha, Arghyotri, Hospital, Audrey, Krauth, Doug, Luengo, Juan I., Kramer, Mike, Pitt, Cameron, Lin, Hong

“…Oncogenic KRAS mutations occur in approximately 25% of all human cancers with KRAS G12V being one of the most frequently occurring variants, particularly in…”
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