Search Results - "Sinha, Anupama"

Extraction and biomolecular analysis of dermal interstitial fluid collected with hollow microneedles by Miller, Philip R., Taylor, Robert M., Tran, Bao Quoc, Boyd, Gabrielle, Glaros, Trevor, Chavez, Victor H., Krishnakumar, Raga, Sinha, Anupama, Poorey, Kunal, Williams, Kelly P., Branda, Steven S., Baca, Justin T., Polsky, Ronen

“…Dermal interstitial fluid (ISF) is an underutilized information-rich biofluid potentially useful in health status monitoring applications whose contents remain…”
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World-to-Digital-Microfluidic Interface Enabling Extraction and Purification of RNA from Human Whole Blood by Jebrail, Mais J, Sinha, Anupama, Vellucci, Samantha, Renzi, Ronald F, Ambriz, Cesar, Gondhalekar, Carmen, Schoeniger, Joseph S, Patel, Kamlesh D, Branda, Steven S

“…Digital microfluidics (DMF) is a powerful technique for simple and precise manipulation of microscale droplets of fluid. This technique enables processing and…”
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Therapeutic efficacy of a potent anti-Venezuelan equine encephalitis virus antibody is contingent on Fc effector function by Schwedler, Jennifer L, Stefan, Maxwell A, Thatcher, Christine E, McIlroy, Peter R, Sinha, Anupama, Phillips, Ashlee M, Sumner, Christopher A, Courtney, Colleen M, Kim, Christina Y, Weilhammer, Dina R, Harmon, Brooke

“…The development of specific, safe, and potent monoclonal antibodies (Abs) has led to novel therapeutic options for infectious disease. In addition to…”
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A microfluidic DNA library preparation platform for next-generation sequencing by Kim, Hanyoup, Jebrail, Mais J, Sinha, Anupama, Bent, Zachary W, Solberg, Owen D, Williams, Kelly P, Langevin, Stanley A, Renzi, Ronald F, Van De Vreugde, James L, Meagher, Robert J, Schoeniger, Joseph S, Lane, Todd W, Branda, Steven S, Bartsch, Michael S, Patel, Kamlesh D

“…Next-generation sequencing (NGS) is emerging as a powerful tool for elucidating genetic information for a wide range of applications. Unfortunately, the…”
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Immunocompromised Cas9 transgenic mice for rapid in vivo assessment of host factors involved in highly pathogenic virus infection by Collette, Nicole, Dhungel, Pragyesh, Lund, Sean J., Schwedler, Jennifer L., Saada, Edwin A., Light, Yooli K., Sinha, Anupama, Schoeniger, Joseph S., Negrete, Oscar A.

“…Targeting host factors for anti-viral development offers several potential advantages over traditional countermeasures that include broad-spectrum activity and…”
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The rotary zone thermal cycler: a low-power system enabling automated rapid PCR by Bartsch, Michael S, Edwards, Harrison S, Lee, Daniel, Moseley, Caroline E, Tew, Karen E, Renzi, Ronald F, Van de Vreugde, James L, Kim, Hanyoup, Knight, Daniel L, Sinha, Anupama, Branda, Steven S, Patel, Kamlesh D

“…Advances in molecular biology, microfluidics, and laboratory automation continue to expand the accessibility and applicability of these methods beyond the…”
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Computational Basis for On-Demand Production of Diversified Therapeutic Phage Cocktails by Mageeney, Catherine M., Sinha, Anupama, Mosesso, Richard A., Medlin, Douglas L., Lau, Britney Y., Rokes, Alecia B., Lane, Todd W., Branda, Steven S., Williams, Kelly P.

“…The antibiotic resistance crisis has led to renewed interest in phage therapy as an alternative means of treating infection. However, conventional methods for…”
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Bromodomain analysis of Brd2-dependent transcriptional activation of cyclin A by Sinha, Anupama, Faller, Douglas V, Denis, Gerald V

“…Cyclin A is regulated primarily through transcription control during the mammalian cell cycle. A dual mechanism of cyclin A transcriptional repression…”
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Tumor-specific and Proliferation-specific Gene Expression Typifies Murine Transgenic B Cell Lymphomagenesis by Lenburg, Marc E., Sinha, Anupama, Faller, Douglas V., Denis, Gerald V.

“…The dual bromodomain protein Brd2 is closely related to the basal transcription factor TAFII250, which is essential for cyclin A transactivation and mammalian…”
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Genome Sequence of the Historical Clinical Isolate Burkholderia pseudomallei PHLS 6 by D'haeseleer, Patrik, Johnson, Shannon L, Davenport, Karen W, Chain, Patrick S, Schoeniger, Joe, Ray, Debjit, Sinha, Anupama, Williams, Kelly P, Peña, José, Branda, Steven S, El-Etr, Sahar

“…Here, we present the draft genome sequence of Burkholderia pseudomallei PHLS 6, a virulent clinical strain isolated from a melioidosis patient in Bangladesh in…”
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Real-Time Selective Sequencing with RUBRIC: Read Until with Basecall and Reference-Informed Criteria by Edwards, Harrison S., Krishnakumar, Raga, Sinha, Anupama, Bird, Sara W., Patel, Kamlesh D., Bartsch, Michael S.

“…The Oxford MinION, the first commercial nanopore sequencer, is also the first to implement molecule-by-molecule real-time selective sequencing or “Read Until”…”
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Real-Time Selective Sequencing with RUBRIC: Read Until with Basecall and Reference-Informed Criteria by Edwards, Harrison S., Krishnakumar, Raga, Sinha, Anupama, Bird, Sara W., Patel, Kamlesh D., Bartsch, Michael S.

“…The Oxford MinION, the first commercial nanopore sequencer, is also the first to implement molecule-bymolecule real-time selective sequencing or "Read Until"…”
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Real-Time Selective Sequencing with RUBRIC: Read Until with Basecall and Reference-Informed Criteria by Edwards, Harrison S., Krishnakumar, Raga, Sinha, Anupama, Bird, Sara W., Patel, Kamlesh D., Bartsch, Michael S.

“…Abstract The Oxford MinION, the first commercial nanopore sequencer, is also the first to implement molecule-by-molecule real-time selective sequencing or…”
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Systematic and stochastic influences on the performance of the MinION nanopore sequencer across a range of nucleotide bias by Krishnakumar, Raga, Sinha, Anupama, Bird, Sara W., Jayamohan, Harikrishnan, Edwards, Harrison S., Schoeniger, Joseph S., Patel, Kamlesh D., Branda, Steven S., Bartsch, Michael S.

“…Emerging sequencing technologies are allowing us to characterize environmental, clinical and laboratory samples with increasing speed and detail, including…”
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A solvent replenishment solution for managing evaporation of biochemical reactions in air-matrix digital microfluidics devices by Jebrail, Mais J, Renzi, Ronald F, Sinha, Anupama, Van De Vreugde, Jim, Gondhalekar, Carmen, Ambriz, Cesar, Meagher, Robert J, Branda, Steven S

“…Digital microfluidics (DMF) is a powerful technique for sample preparation and analysis for a broad range of biological and chemical applications. In many…”
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Whole‐Cell MALDI‐ToF MS Coupled with Untargeted Metabolomics Facilitates Investigations of Microbial Chemical Interactions by Aiosa, Nicole, Sinha, Anupama, Albataineh, Hanan, Phillips, Ashlee M., Mageeney, Catherine M., Wilde, Delaney S., Williams, Kelly P., Collette, Nicole M., Branda, Steven S., Garg, Neha

“…The emergence of drug‐resistant pathogens necessitates the development of new countermeasures. In this regard, the introduction of probiotics to directly…”
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Publisher Correction: Real-Time Selective Sequencing with RUBRIC: Read Until with Basecall and Reference-Informed Criteria by Edwards, Harrison S., Krishnakumar, Raga, Sinha, Anupama, Bird, Sara W., Patel, Kamlesh D., Bartsch, Michael S.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Experimental single-strain mobilomics reveals events that shape pathogen emergence by Schoeniger, Joseph S, Hudson, Corey M, Bent, Zachary W, Sinha, Anupama, Williams, Kelly P

“…Virulence genes on mobile DNAs such as genomic islands (GIs) and plasmids promote bacterial pathogen emergence. Excision is an early step in GI mobilization,…”
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Metabolomics Analysis of Bacterial Pathogen Burkholderia thailandensis and Mammalian Host Cells in Co-culture by Aiosa, Nicole, Sinha, Anupama, Jaiyesimi, Olakunle A., da Silva, Ricardo R., Branda, Steven S., Garg, Neha

“…The Tier 1 HHS/USDA Select Agent Burkholderia pseudomallei is a bacterial pathogen that is highly virulent when introduced into the respiratory tract and…”
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Transcriptomic Analysis of Yersinia enterocolitica Biovar 1B Infecting Murine Macrophages Reveals New Mechanisms of Extracellular and Intracellular Survival by Bent, Zachary W, Poorey, Kunal, Brazel, David M, LaBauve, Annette E, Sinha, Anupama, Curtis, Deanna J, House, Samantha E, Tew, Karen E, Hamblin, Rachelle Y, Williams, Kelly P, Branda, Steven S, Young, Glenn M, Meagher, Robert J

“…Yersinia enterocolitica is typically considered an extracellular pathogen; however, during the course of an infection, a significant number of bacteria are…”
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