Search Results - "Sinha, Akhouri A."

Identification of metastatic cell nucleus in human prostate cancer by electron microscopy by Sinha, Akhouri A

“…Metastatic prostate cancer is responsible for a large proportion of deaths worldwide. The aim of this study was to identify metastatic cells and determine if…”
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Electron Microscopic Analysis of Stem Cells in Human Prostate Cancer, Including Inverted Capsule Embedding Methods for Archival Sections and Falcon Films for Prostate Cancer Cell Lines by Sinha, Akhouri A

“…Identification of prostatic stem cells in primary prostate tissue sections, organ cultures of prostate and cell lines requires a range of techniques that…”
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Patterns, Art, and Context: Donald Floyd Gleason and the Development of the Gleason Grading System by Phillips, John L, Sinha, Akhouri A

“…The Gleason grading system is a standard method of assessing prostate cancer. Very little is known, however, about the person behind the system, Donald Floyd…”
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Identification of Two Types of Stem Cells in Methylene Blue-stained Sections of Untreated and Diethylstilbestrol-treated Human Prostate Cancer and Their Characterization by Immunogold Localization of CD133 by Sinha, Akhouri A, Wilson, Michael J

“…The basal compartment of the prostatic acinus harbors stem and basal cells, whereas the luminal compartment contains cuboidal and columnar cells. Mutation in…”
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Cathepsin B Expression is Similar in African-American and Caucasian Prostate Cancer Patients by SINHA, Akhouri A, MORGAN, Jenifer L, BUUS, Ryan J, EWING, Stephen L, FERNANDES, Eduardo T, LE, Chap, WILSON, Michael J

“…Background: Increased incidence and mortality of prostate cancer (PCa) suggest that U.S. African-American men have more invasive cancer than Caucasian men…”
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Cathepsin B Expression in Prostate Cancer of Native Japanese and Japanese-American Patients: An Immunohistochemical Study by SINHA, Akhouri A, MORGAN, Jenifer L, BETRE, Konjit, WILSON, Michael J, LE, Chap, MARKS, Leonard S

“…Background: Japanese-American (J-A) men who have immigrated to the U.S.A. and acquired the Western lifestyle usually have more invasive prostate cancer (PCa)…”
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Heterogeneity of Cathepsin B and Stefin A Expression in Gleason Pattern 3+3 (Score 6) Prostate Cancer Needle Biopsies by SINHA, Akhouri A, MORGAN, Jenifer L, WOOD, Nada, BETRE, Konjit, REDDY, Avinash, WILSON, Michael J, RAMANANI, Dharam M

“…Background: There is a significant positive association of increased ratios of cathepsin B to its endogenous inhibitor stefin (cystatin) A in prostatectomy…”
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Concurrent Androgen and Estrogen Ablation and Inhibition of Steroid Biosynthetic Enzyme Treatment for Castration-resistant Prostate Cancer by Sinha, Akhouri A, Pomroy, Jr, Francis E, Wilson, Michael J

“…About 80 to 90% of prostate cancer (PCa) is androgen-dependent at diagnosis, but patients ultimately develop castration-resistant prostate cancer (CRPC), which…”
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Induction of a heparin-stimulated serine proteinase in sex accessory gland tumors of the Lobund-Wistar rat by Wilson, Michael J., Lind, Jeremy, Sinha, Akhouri A.

“…Induction of new proteinase activities that may process growth factors, modify cell surface receptors, cleave extracellular matrix proteins, etc. is considered…”
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Matrix metalloproteinase and heparin-stimulated serine proteinase activities in post-prostate massage urine of men with prostate cancer by Muñoz, David, Serrano, Maria K., Hernandez, Maria E., Haller, Ross, Swanson, Tamara, Slaton, Joel W., Sinha, Akhouri A., Wilson, Michael J.

“…Proteinases secreted by the prostate gland have a reproductive function in cleaving proteins in the ejaculate and in the female reproductive tract, but some…”
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Prediction of immune surveillance responsive metastatic prostate cancer in pelvic lymph node and emergence of surveillance unresponsive/resistant metastatic cells by Sinha, Akhouri A, Fernandes, Eduardo T, Ewing, Stephen L, Wilson, Michael J

“…Immune cells (lymphocytes and macrophages) provide the microenvironment for immune surveillance of metastatic prostate cancer (PCa) cells in pelvic lymph…”
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Dipeptidylpeptidase IV activities are elevated in prostate cancers and adjacent benign hyperplastic glands by Wilson, M. J, Ruhland, A. R, Quast, B. J, Reddy, P. K, Ewing, S. L, Sinha, A. A

“…Dipeptidylpeptidase IV (DPP IV) is a serine exopeptidase that has been implicated in cell‐extracellular matrix interactions and bioactive…”
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The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund–Wistar rats by Wilson, Michael J., Lindgren, Bruce R., Sinha, Akhouri A.

“…Prostate cancer, the most prevalent non-cutaneous cancer in men, is associated with increased age. This suggests that dietary chemopreventive measures could be…”
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Characterization of Prostate Cancer in Needle Biopsy by Cathepsin B, Cell Proliferation and DNA Ploidy by JUNQI QIAN, BOSTWICK, David G, ICZKOWSKI, Kenneth A, BETRE, Konjit, WILSON, Michael J, CHAP LE, SINHA, AkhouriA

“…Our objective was to determine localization patterns of three distinct groups of biomarkers (cathepsin B, MIB-1 and DNA ploidy) in prostate needle biopsy…”
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Elevation of dipeptidylpeptidase iv activities in the prostate peripheral zone and prostatic secretions of men with prostate cancer: possible prostate cancer disease marker by Wilson, Michael J, Haller, Ross, Li, Shelby Y, Slaton, Joel W, Sinha, Akhouri A, Wasserman, Neil F

“…Dipeptidylpeptidase IV (DPIV) is a multifunctional type II plasma membrane glycoprotein with serine-type exopeptidase activity that is secreted by the prostate…”
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Prediction of pelvic lymph node metastasis by the ratio of cathepsin B to stefin A in patients with prostate carcinoma by Sinha, Akhouri A., Quast, Barry J., Wilson, Michael J., Fernandes, Eduardo T., Reddy, Pratap K., Ewing, Stephen L., Gleason, Donald F.

“…BACKGROUND Pathologic grade and/or histologic score, extraprostatic extension indicated by invasion of the prostatic capsule, margin, and/or seminal vesicles…”
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Matrix metalloproteinases in the pathogenesis of estradiol-induced nonbacterial prostatitis in the lateral prostate lobe of the Wistar rat by Wilson, Michael J, Woodson, Mildred, Wiehr, Carol, Reddy, Avinash, Sinha, Akhouri A

“…Chronic nonbacterial prostatitis develops spontaneously with age in the lateral lobe of the prostate in some strains of rat. Our objective was to examine the…”
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Increased Aggressiveness of Human Prostate PC-3 Tumor Cells Expressing Cell Surface Localized Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) by Wang, Xing, Wilson, Michael J, Slaton, Joel W, Sinha, Akhouri A, Ewing, Stephen L, Pei, Duanqing

“…Membrane type‐1 matrix metalloproteinase (MT1‐MMP) is a multidomain transmembrane endopeptidase with a major role in physiological and pathological processes…”
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Plasma membrane association of cathepsin B in human prostate cancer: Biochemical and immunogold electron microscopic analysis by Sinha, Akhouri A., Jamuar, Mahendra P., Wilson, Michael J., Rozhin, Jurij, Sloane, Bonnie F.

“…Background Cathepsin B (CB), a cysteine protease, is usually found in perinuclear lysosomes of epithelial cells of normal organs and non‐malignant tumors, but…”
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Microvessel density as a molecular marker for identifying high-grade prostatic intraepithelial neoplasia precursors to prostate cancer by Sinha, Akhouri A., Quast, Barry J., Reddy, Pranav K., Lall, Vikas, Wilson, Michael J., Qian, Jungi, Bostwick, DavidG

“…Background: Existing clinical data have shown that high-grade prostatic intraepithelial neoplasia (HGPIN) is the most likely precursor to prostate cancer…”
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