Search Results - "Singleton, KD"

Glutamine attenuates lung injury and improves survival after sepsis: Role of enhanced heat shock protein expression by Singleton, Kristen D, Serkova, Natalie, Beckey, Virgina E, Wischmeyer, Paul E

“…OBJECTIVE:Heat shock protein (HSP) expression is vital to cellular and tissue protection after stress or injury. However, application of this powerful tool in…”
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Glutamine prevents activation of NF-κB and stress kinase pathways, attenuates inflammatory cytokine release, and prevents acute respiratory distress syndrome (ARDS) following sepsis by SINGLETON, Kristen D, BECKEY, Virginia E, WISCHMEYER, Paul E

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Parenteral glutamine increases serum heat shock protein 70 in critically ill patients by ZIEGLER, Thomas R, OGDEN, Lorraine G, SINGLETON, Kristen D, MENGHUA LUO, FERNANDEZ-ESTIVARIZ, Concepcion, GRIFFITH, Daniel P, GALLOWAY, John R, WISCHMEYER, Paul E

“…Heat shock protein 70 (HSP-70) is protective against cellular and tissue injury. Increased serum HSP-70 levels are associated with decreased mortality in…”
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Oral glutamine enhances heat shock protein expression and improves survival following hyperthermia by SINGLETON, Kristen D, WISCHMEYER, Paul E

“…No pharmacologic agent has shown benefit in treating heatstroke. Previous data indicate that enhanced heat shock protein 70 (HSP-70) expression can improve…”
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Effects of HSP70.1/3 gene knockout on acute respiratory distress syndrome and the inflammatory response following sepsis by Singleton, Kristen D, Wischmeyer, Paul E

“…Heat shock response has been implicated in attenuating NF-kappaB activation and inflammation following sepsis. Studies utilizing sublethal heat stress or…”
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Glutamine's protection against cellular injury is dependent on heat shock factor-1 by Morrison, Angela L, Dinges, Martin, Singleton, Kristen D, Odoms, Kelli, Wong, Hector R, Wischmeyer, Paul E

“…Glutamine (GLN) has been shown to protect cells, tissues, and whole organisms from stress and injury. Enhanced expression of heat shock protein (HSP) has been…”
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Glutamine attenuates tumor necrosis factor-α release and enhances heat shock protein 72 in human peripheral blood mononuclear cells by Wischmeyer, Paul E, Riehm, Jacob, Singleton, Kristen D, Ren, Hongyu, Musch, Mark W, Kahana, Madelyn, Chang, Eugene B

“…Overexpression of pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) can contribute to multiple organ dysfunction syndrome and septic shock in…”
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Distance of cecum ligated influences mortality, tumor necrosis factor-alpha and interleukin-6 expression following cecal ligation and puncture in the rat by Singleton, K D, Wischmeyer, P E

“…A mainstay of laboratory research into new therapies for sepsis has been the cecal ligation and puncture (CLP) model in rodents. Previous data indicate that…”
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Glutamine attenuates endotoxin-induced lung metabolic dysfunction: Potential role of enhanced heat shock protein 70 by Singleton, Kristen D., Serkova, Natalie, Banerjee, Anirban, Meng, Xianzhong, Gamboni-Robertson, Fabia, Wischmeyer, Paul E.

“…Septic shock leads to derangement of cellular metabolism. Enhanced heat shock protein 70 (HSP-70) can preserve cellular metabolism after other forms of…”
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Single dose of glutamine enhances myocardial tissue metabolism, glutathione content, and improves myocardial function after ischemia-reperfusion injury by Wischmeyer, PE, Jayakar, D, Williams, U, Singleton, KD, Riehm, J, Bacha, EA, Jeevanandam, V, Christians, U, Serkova, N

“…BACKGROUND: Myocardial ischemia and reperfusion (I/R) injury causes significant morbidity and mortality. Protection against I/R injury may occur via…”
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