Search Results - "Singleton, Eileen W"

A targeted CRISPR-Cas9 mediated F0 screen identifies genes involved in establishment of the enteric nervous system by Moreno-Campos, Rodrigo, Singleton, Eileen W, Uribe, Rosa A

“…The vertebrate enteric nervous system (ENS) is a crucial network of enteric neurons and glia resident within the entire gastrointestinal tract (GI). Overseeing…”
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An atlas of neural crest lineages along the posterior developing zebrafish at single-cell resolution by Howard, 4th, Aubrey Ga, Baker, Phillip A, Ibarra-García-Padilla, Rodrigo, Moore, Joshua A, Rivas, Lucia J, Tallman, James J, Singleton, Eileen W, Westheimer, Jessa L, Corteguera, Julia A, Uribe, Rosa A

“…Neural crest cells (NCCs) are vertebrate stem cells that give rise to various cell types throughout the developing body in early life. Here, we utilized…”
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Elevated Hoxb5b Expands Vagal Neural Crest Pool and Blocks Enteric Neuronal Development in Zebrafish by Howard, 4th, Aubrey G A, Nguyen, Aaron C, Tworig, Joshua, Ravisankar, Priya, Singleton, Eileen W, Li, Can, Kotzur, Grayson, Waxman, Joshua S, Uribe, Rosa A

“…Neural crest cells (NCCs) are a migratory, transient, and multipotent stem cell population essential to vertebrate embryonic development, contributing to…”
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Expansion of a neural crest gene signature following ectopic MYCN expression in sympathoadrenal lineage cells in vivo by Ibarra-García-Padilla, Rodrigo, Nambiar, Annika, Hamre, Thomas A, Singleton, Eileen W, Uribe, Rosa A

“…Neural crest cells (NCC) are multipotent migratory stem cells that originate from the neural tube during early vertebrate embryogenesis. NCCs give rise to a…”
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BMP signaling pathway member expression is enriched in enteric neural progenitors and required for zebrafish enteric nervous system development by Moore, Joshua A, Moreno-Campos, Rodrigo, Noah, Arielle S, Singleton, Eileen W, Uribe, Rosa A

“…The vertebrate enteric nervous system (ENS) consists of a series of interconnected ganglia within the gastrointestinal (GI) tract, formed during development…”
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In toto imaging of early enteric nervous system development reveals that gut colonization is tied to proliferation downstream of Ret by Baker, Phillip A, Ibarra-García-Padilla, Rodrigo, Venkatesh, Akshaya, Singleton, Eileen W, Uribe, Rosa A

“…The enteric nervous system is a vast intrinsic network of neurons and glia within the gastrointestinal tract and is largely derived from enteric neural crest…”
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Engineering oxidative stability in human hemoglobin based on the Hb providence (βK82D) mutation and genetic cross-linking by Strader, Michael Brad, Bangle, Rachel, Parker Siburt, Claire J, Varnado, Cornelius L, Soman, Jayashree, Benitez Cardenas, Andres S, Samuel, Premila P, Singleton, Eileen W, Crumbliss, Alvin L, Olson, John S, Alayash, Abdu I

“…Previous work suggested that hemoglobin (Hb) tetramer formation slows autoxidation and hemin loss and that the naturally occurring mutant, Hb Providence…”
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Determination of ligand pathways in globins: apolar tunnels versus polar gates by Salter, Mallory D, Blouin, George C, Soman, Jayashree, Singleton, Eileen W, Dewilde, Sylvia, Moens, Luc, Pesce, Alessandra, Nardini, Marco, Bolognesi, Martino, Olson, John S

“…Although molecular dynamics simulations suggest multiple interior pathways for O(2) entry into and exit from globins, most experiments indicate well defined…”
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Determination of Ligand Pathways in Globins by Salter, Mallory D., Blouin, George C., Soman, Jayashree, Singleton, Eileen W., Dewilde, Sylvia, Moens, Luc, Pesce, Alessandra, Nardini, Marco, Bolognesi, Martino, Olson, John S.

“…Although molecular dynamics simulations suggest multiple interior pathways for O2 entry into and exit from globins, most experiments indicate well defined…”
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A targeted CRISPR-Cas9 mediated F0 screen identifies genes involved in establishment of the enteric nervous system by Rodrigo Moreno-Campos, Eileen W Singleton, Rosa A Uribe

“…The vertebrate enteric nervous system (ENS) is a crucial network of enteric neurons and glia resident within the entire gastrointestinal tract (GI). Overseeing…”
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S13.37 A sperm whale myoglobin as protein model of cytochrome a3: The role of heme propionates by Fabian, Marian, Singleton, Eileen W., Soman, Jayashree, Olson, John S.

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A novel site-directed mutant of myoglobin with an unusually high O2 affinity and low autooxidation rate by T E Carver, R E Brantley, Jr, E W Singleton, R M Arduini, M L Quillin, G N Phillips, Jr, J S Olson

“…Mutants of sperm whale myoglobin were constructed at position 29 (B10 in helix notation) to examine the effects of distal pocket size on the rates of ligand…”
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