Search Results - "Singhal, Sonia"
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Novel intraoperative near-infrared imaging strategy to identify abnormalities in the anterior mediastinum
Published in Journal of cardiothoracic surgery (09-12-2022)“…Thoracic surgeons are frequently asked to biopsy suspicious tissues in the anterior mediastinum to discriminate between a reactive versus malignant pathology…”
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Experimental Evolution Studies in Φ6 Cystovirus
Published in Viruses (01-06-2024)“…Experimental evolution studies, in which biological populations are evolved in a specific environment over time, can address questions about the nature of…”
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Adaptations of an RNA virus to increasing thermal stress
Published in PloS one (21-12-2017)“…Environments can change in incremental fashions, where a shift from one state to another occurs over multiple organismal generations. The rate of the…”
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Development of genomic resources for a thraustochytrid pathogen and investigation of temperature influences on gene expression
Published in PloS one (17-09-2013)“…Understanding how environmental changes influence the pathogenicity and virulence of infectious agents is critical for predicting epidemiological patterns of…”
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Digest: Structuring interactions in Streptomyces
Published in Evolution (01-01-2020)“…For bacteria growing in colonies, spatial structure can allow maintenance of costly traits such as the production of antibiotics. Using spatially structured…”
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Digest: Unpacking fitness effects of spontaneous mutations: DIGEST
Published in Evolution (01-12-2017)Get full text
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Digest: Unpacking fitness effects of spontaneous mutations
Published in Evolution (01-12-2017)Get full text
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Digest: Beating pathogens at their own game
Published in Evolution (01-03-2017)Get full text
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Digest: Beating pathogens at their own game: DIGESTS
Published in Evolution (01-03-2017)Get full text
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Effects of historical co-infection on host shift abilities of exploitative and competitive viruses
Published in Evolution (01-07-2021)“…Rapid evolution contributes to frequent emergence of RNA viral pathogens on novel hosts. However, accurately predicting which viral genotypes will emerge has…”
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Digest: Investigating reproductive isolation in test tubes
Published in Evolution (01-08-2020)“…Reproductive isolation can result from incompatibilities between mutations that arise in different individuals. Wang and Cooper examined this mechanism of…”
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Digest: Less than the sum of its parts: Negative epistasis in bacterial swarming
Published in Evolution (01-04-2017)Get full text
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13
Recombination drives the evolution of mutational robustness
Published in Current opinion in systems biology (01-02-2019)“…Recombination can impose fitness costs as beneficial parental combinations of alleles are broken apart, a phenomenon known as recombination load. Computational…”
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Effects of Single Mutations from Experimental Evolution of Microbial Proteins: Thermostability in 6 Cystovirus and Toxin Diversification in Escherichia coli
Published 01-01-2017“…Experimental and directed evolution using microbes offer powerful methods for uncovering processes of evolution across the tree of life. The goal of such…”
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Dissertation -
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Host demography influences the prevalence and severity of eelgrass wasting disease
Published in Diseases of aquatic organisms (19-02-2014)“…Many marine pathogens are opportunists, present in the environment, but causing disease only under certain conditions such as immunosuppression due to…”
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Constraint analysis and debugging for multi-million instance SoC designs
Published in 2010 11th International Symposium on Quality Electronic Design (ISQED) (01-03-2010)“…Timing constraints are used by implementation tools in all design stages in modern design flows. With the growing complexity of designs and constraints, it is…”
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Conference Proceeding -
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Development of Genomic Resources for a thraustochytrid Pathogen and Investigation of Temperature Influences on Gene Expression: e74196
Published in PloS one (01-09-2013)“…Understanding how environmental changes influence the pathogenicity and virulence of infectious agents is critical for predicting epidemiological patterns of…”
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Journal Article -
18
Practical, fast Monte Carlo statistical static timing analysis: Why and how
Published in 2008 IEEE/ACM International Conference on Computer-Aided Design (01-11-2008)“…Statistical static timing analysis (SSTA) has emerged as an essential tool for nanoscale designs. Monte Carlo methods are universally employed to validate the…”
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Conference Proceeding -
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Exploiting correlation kernels for efficient handling of intra-die spatial correlation, with application to statistical timing
Published in Proceedings of the conference on Design, automation and test in Europe (10-03-2008)“…Intra-die manufacturing variations are unavoidable in nanoscale processes. These variations often exhibit strong spatial correlation. Standard grid-based…”
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Conference Proceeding