Search Results - "Singh Arya, Dharamvir"

Up-regulation of PPARγ, heat shock protein-27 and -72 by naringin attenuates insulin resistance, β-cell dysfunction, hepatic steatosis and kidney damage in a rat model of type 2 diabetes by Kumar Sharma, Ashok, Bharti, Saurabh, Ojha, Shreesh, Bhatia, Jagriti, Kumar, Narender, Ray, Ruma, Kumari, Santosh, Singh Arya, Dharamvir

“…Naringin, a bioflavonoid isolated from grapefruit, is well known to possess lipid-lowering and insulin-like properties. Therefore, we assessed whether naringin…”
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Pharmacological Properties and Therapeutic Potential of Naringenin: A Citrus Flavonoid of Pharmaceutical Promise by Rani, Neha, Bharti, Saurabh, Krishnamurthy, Bhaskar, Bhatia, Jagriti, Sharma, Charu, Kamal, Mohammad Amjad, Ojha, Shreesh, Arya, Dharamvir Singh

“…Naringenin chemically known as 5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one is a common dietary polyphenolic constituent of the citrus fruits. It has…”
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Naringin Protects against Kainic Acid-Induced Status Epilepticus in Rats: Evidence for an Antioxidant, Anti-inflammatory and Neuroprotective Intervention by Golechha, Mahaveer, Chaudhry, Uma, Bhatia, Jagriti, Saluja, Daman, Arya, Dharamvir Singh

“…The effect of naringin, a bioflavanoid, with potent antioxidant activity was studied on kainic acid (KA)-induced seizures, cognitive deficit and oxidative…”
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Syzygium cumini Ameliorates Insulin Resistance and β-Cell Dysfunction via Modulation of PPARγ, Dyslipidemia, Oxidative Stress, and TNF-α in Type 2 Diabetic Rats by Sharma, Ashok Kumar, Bharti, Saurabh, Kumar, Rajiv, Krishnamurthy, Bhaskar, Bhatia, Jagriti, Kumari, Santosh, Arya, Dharamvir Singh

“…Syzygium cumini (SC) is well known for its anti-diabetic potential, but the mechanism underlying its amelioration of type 2 diabetes is still elusive…”
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Understanding long COVID myocarditis: A comprehensive review by Srivastava, Arti, Nalroad Sundararaj, Shankar, Bhatia, Jagriti, Singh Arya, Dharamvir

“…•Myocarditis, a long-term complication of coronavirus disease 2019 (COVID-19) is an inflammatory condition involving the myocardium of the heart. The interplay…”
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Role of MAPK/NF-κB pathway in cardioprotective effect of Morin in isoproterenol induced myocardial injury in rats by Verma, Vipin Kumar, Malik, Salma, Narayanan, Susrutha P., Mutneja, Ekta, Sahu, Anil Kumar, Bhatia, Jagriti, Arya, Dharamvir Singh

“…Oxidative stress plays a major role in myocardial injury. Morin, a bioflavonoid has known to possess various biological activities in previous studies. Hence,…”
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The dietary isoflavone daidzein mitigates oxidative stress, apoptosis, and inflammation in CDDP‐induced kidney injury in rats: Impact of the MAPK signaling pathway by Tomar, Ameesha, Kaushik, Swati, Khan, Sana Irfan, Bisht, Khushboo, Nag, Tapas Chandra, Arya, Dharamvir Singh, Bhatia, Jagriti

“…Cisplatin‐induced nephrotoxicity persists as a clinical problem despite several supportive measures to alleviate renal damage. Daidzein (DZ), a dietary…”
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Hesperidin regresses cardiac hypertrophy by virtue of PPAR‐γ agonistic, anti‐inflammatory, antiapoptotic, and antioxidant properties by Bhargava, Poorva, Verma, Vipin Kumar, Malik, Salma, Khan, Sana Irfan, Bhatia, Jagriti, Arya, Dharamvir Singh

“…Hesperidin (HES), a flavanone glycoside, predominant in citrus fruits, has an agonistic activity on peroxisome proliferator‐activated receptor gamma (PPAR‐γ)…”
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Targeting AGE‐RAGE signaling pathway by Saxagliptin prevents myocardial injury in isoproterenol challenged diabetic rats by Kumar, Rajiv, Bhargava, Poorva, Suchal, Kapiil, Bhatia, Jagriti, Arya, Dharamvir Singh

“…The role of Saxagliptin in diabetes‐associated cardiovascular complications is controversial. This study aimed to investigate whether Saxagliptin could prevent…”
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Hesperidin produces cardioprotective activity via PPAR-γ pathway in ischemic heart disease model in diabetic rats by Agrawal, Yogeeta O, Sharma, Pankaj Kumar, Shrivastava, Birendra, Ojha, Shreesh, Upadhya, Harshita M, Arya, Dharamvir Singh, Goyal, Sameer N

“…The present study investigated the effect of hesperidin, a natural flavonoid, in cardiac ischemia and reperfusion (I/R) injury in diabetic rats. Male Wistar…”
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Molecular Pathways Involved in the Amelioration of Myocardial Injury in Diabetic Rats by Kaempferol by Suchal, Kapil, Malik, Salma, Khan, Sana Irfan, Malhotra, Rajiv Kumar, Goyal, Sameer N, Bhatia, Jagriti, Ojha, Shreesh, Arya, Dharamvir Singh

“…There is growing evidence that chronic hyperglycemia leads to the formation of advanced glycation end products (AGEs) which exerts its effect via interaction…”
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Metformin alleviates bleomycin-induced pulmonary fibrosis in rats: Pharmacological effects and molecular mechanisms by Gamad, Nanda, Malik, Salma, Suchal, Kapil, Vasisht, Swati, Tomar, Ameesha, Arava, Sudheer, Arya, Dharamvir Singh, Bhatia, Jagriti

“…Metformin, a commonly used oral antidiabetic agent, is known to possess pleiotropic antioxidant, anti-inflammatory and anti-fibrotic effects. In this study, we…”
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Abatacept: A Promising Repurposed Solution for Myocardial Infarction-Induced Inflammation in Rat Models by Verma, Vipin Kumar, Mutneja, Ekta, Malik, Salma, Sahu, Anil Kumar, Prajapati, Vaishali, Bhardwaj, Priya, Ray, Ruma, Nag, Tapas Chandra, Bhatia, Jagriti, Arya, Dharamvir Singh

“…Myocardial infarction (MI) is irreversible damage to the myocardial tissue caused by prolonged ischemia/hypoxia, subsequently leading to loss of contractile…”
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Akt/GSK-3β/eNOS phosphorylation arbitrates safranal-induced myocardial protection against ischemia–reperfusion injury in rats by Bharti, Saurabh, Golechha, Mahaveer, Kumari, Santosh, Siddiqui, Khalid Mehmood, Arya, Dharamvir Singh

“…Purpose Traditional medicine has been appropriately identified as the most productive soil for the cultivation and harvesting of modern medicines. Herein, we…”
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Protective Effects of Cardamom in Isoproterenol-Induced Myocardial Infarction in Rats by Goyal, Sameer N, Sharma, Charu, Mahajan, Umesh B, Patil, Chandragouda R, Agrawal, Yogeeta O, Kumari, Santosh, Arya, Dharamvir Singh, Ojha, Shreesh

“…Cardamom is a popular spice that has been commonly used in cuisines for flavor since ancient times. It has copious health benefits such as improving digestion,…”
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Mangiferin attenuates cisplatin-induced acute kidney injury in rats mediating modulation of MAPK pathway by Sahu, Anil Kumar, Verma, Vipin Kumar, Mutneja, Ekta, Malik, Salma, Nag, Tapas Chandra, Dinda, Amit Kumar, Arya, Dharamvir Singh, Bhatia, Jagriti

“…Cisplatin has been confined due to the reported cases of nephrotoxicity. In the present study, an active xanthone, Mangiferin (from Mangifera indica ) was…”
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Pitavastatin attenuates cisplatin‐induced renal injury by targeting MAPK and apoptotic pathways by Kaushik, Swati, Tomar, Ameesha, Puthanmadhom Narayanan, Susrutha, Nag, Tapas Chandra, Arya, Dharamvir Singh, Bhatia, Jagriti

“…Objective Anti‐neoplastic drug cisplatin is prescribed widely for treatment of a variety of malignancies. Its use has been restricted lately due to severe…”
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The Protective Effect of Apigenin on Myocardial Injury in Diabetic Rats mediating Activation of the PPAR-γ Pathway by Mahajan, Umesh B, Chandrayan, Govind, Patil, Chandragouda R, Arya, Dharamvir Singh, Suchal, Kapil, Agrawal, Yogeeta O, Ojha, Shreesh, Goyal, Sameer N

“…We substantiated the role of peroxisome proliferator-activated receptor-γ (PPAR-γ) activation in the protective effect of apigenin against the myocardial…”
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Cardioprotective effects of azilsartan compared with that of telmisartan on an in vivo model of myocardial ischemia‐reperfusion injury by Garg, Shanky, Khan, Sana Irfan, Malhotra, Rajiv Kumar, Sharma, Manish Kumar, Kumar, Manoj, Kaur, Punit, Nag, Tapas Chandra, Ray, Ruma, Bhatia, Jagriti, Arya, Dharamvir Singh

“…Azilsartan is found to be more potent than other angiotensin receptor blockers in reducing blood pressure. However, its effect on the heart following…”
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Kaempferol Attenuates Myocardial Ischemic Injury via Inhibition of MAPK Signaling Pathway in Experimental Model of Myocardial Ischemia-Reperfusion Injury by Arya, Dharmveer S., Ojha, Shreesh, Chaudhary, Uma, Goyal, Sameer N., Malhotra, Rajiv Kumar, Gamad, Nanda, Malik, Salma, Suchal, Kapil, Bhatia, Jagriti

“…Kaempferol (KMP), a dietary flavonoid, has antioxidant, anti-inflammatory, and antiapoptotic effects. Hence, we investigated the effect of KMP in…”
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