Search Results - "Singh, Sushil K."

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  1. 1

    Benzothiazoles: how relevant in cancer drug design strategy? by Singh, Meenakshi, Singh, Sushil K

    Published in Anti-cancer agents in medicinal chemistry (01-01-2014)
    “…Heterocyclic compounds, analogs and derivatives have attracted attention due to their diverse biological and pharmacological properties. Benzoheterocycles such…”
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    Design and Synthesis of Novel Schiff Base-Benzothiazole Hybrids as Potential Epidermal Growth Factor Receptor (EGFR) Inhibitors by Singh, Meenakshi, Singh, Sudhir Kumar, Thakur, Bhushan, Ray, Pritha, Singh, Sushil K

    Published in Anti-cancer agents in medicinal chemistry (01-01-2016)
    “…A series of novel Schiff bases -benzothiazole hybrids was designed, synthesized and evaluated for their anticancer activity by MTT assay and western blot…”
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    Effect of sulfonamide derivatives of phenylglycine on scopolamine‐induced amnesia in rats by Ganeshpurkar, Ankit, Singh, Ravi, Tripathi, Pratigya, Alam, Qadir, Krishnamurthy, Sairam, Kumar, Ashok, Singh, Sushil K.

    Published in Ibrain (01-03-2023)
    “…Alzheimer's disease is a neurodegenerative disease responsible for dementia and other neuropsychiatric symptoms. In the present study, compounds 30 and 33,…”
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    Naphthalene, a versatile platform in medicinal chemistry: Sky-high perspective by Makar, Subhajit, Saha, Tanmay, Singh, Sushil K.

    Published in European journal of medicinal chemistry (01-01-2019)
    “…Naphthalene, a cytotoxic moiety, is an extensively explored aromatic conjugated system with applications in various pathophysiological conditions viz…”
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    Estrogen signaling: An emanating therapeutic target for breast cancer treatment by Saha, Tanmay, Makar, Subhajit, Swetha, Rayala, Gutti, Gopichand, Singh, Sushil K.

    Published in European journal of medicinal chemistry (01-09-2019)
    “…Breast cancer, a most common malignancy in women, was known to be associated with steroid hormone estrogen. The discovery of estrogen receptor (ER) gave us not…”
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    In-vitro scolicidal activity of Mallotus philippinensis (Lam.) Muell Arg. fruit glandular hair extract against hydatid cyst Echinococcus granulosus by Gangwar, Mayank, Verma, Vijay C, Singh, Tryambak D, Singh, Sushil K, Goel, R K, Nath, Gopal

    Published in Asian Pacific journal of tropical medicine (01-08-2013)
    “…To investigate new scolicidal agent from natural resources to cope with the side effects associated with synthetic drugs in Echinococcosis. The scolicidal…”
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  7. 7

    Near-Infrared Fluorescent Probes as Imaging and Theranostic Modalities for Amyloid-Beta and Tau Aggregates in Alzheimer’s Disease by Rai, Himanshu, Gupta, Sarika, Kumar, Saroj, Yang, Jian, Singh, Sushil K., Ran, Chongzhao, Modi, Gyan

    Published in Journal of medicinal chemistry (14-07-2022)
    “…A person suspected of having Alzheimer’s disease (AD) is clinically diagnosed for the presence of principal biomarkers, especially misfolded amyloid-beta (Aβ)…”
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  8. 8

    Delayed perforation of the right ventricle by pacemaker/automated implantable cardioverter-defibrillator lead: A single-center experience by Sarvesh Kumar, Vivek Tewarson, Mohammad Zeeshan Hakim, Shobhit Kumar, Sushil K Singh

    Published in Heart India (01-01-2021)
    “…Introduction: Cardiac perforation by pacemaker/automatic implantable cardioverter-defibrillator (AICD) lead can be a life-threatening emergency. Delayed…”
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    Identification of selective MMP-9 inhibitors through multiple e-pharmacophore, ligand-based pharmacophore, molecular docking, and density functional theory approaches by Jana, Srabanti, Singh, Sushil K.

    “…Matrix metalloproteinase-9 (MMP-9) is a significant target for the development of drugs for the treatment of arthritis, CNS disorders, and cancer metastasis…”
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    Effect of feed moisture, extrusion temperature and screw speed on properties of soy white flakes based aquafeed: a response surface analysis by Singh, Sushil K, Muthukumarappan, Kasiviswanathan

    “…BACKGROUND Soy white flakes (SWF) is an intermediate product during soy bean processing. It is an untoasted inexpensive product and contains around 51% of…”
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  12. 12

    Discovery of reversible selective monoamine oxidase B inhibitors with anti-acetylcholinesterase activity derived from 4-oxo-N-4-diphenyl butanamides by Jana, Srabanti, Nasreen, Tania, Singh, Sushil K

    Published in Future medicinal chemistry (01-01-2023)
    “…Multitargeted drugs are essential for the treatment of various neurodegenerative disorders, because of their complex nature. This study aimed to develop novel…”
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    Development of Piperazinediones as dual inhibitor for treatment of Alzheimer's disease by Kumar, Devendra, Gupta, Sukesh K., Ganeshpurkar, Ankit, Gutti, Gopichand, Krishnamurthy, Sairam, Modi, Gyan, Singh, Sushil K.

    Published in European journal of medicinal chemistry (25-04-2018)
    “…Novel multifunctional 3,6-Diphenyl-1,4-bis(phenylsulfonyl)piperazine-2,5-dione derivatives were designed and synthesized for the treatment of Alzheimer's…”
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    α-Synuclein aggregation modulation: an emerging approach for the treatment of Parkinson's disease by Singh, Sushil K, Dutta, Aloke, Modi, Gyan

    Published in Future medicinal chemistry (01-06-2017)
    “…Parkinson's disease (PD) is a multifactorial progressive neurological disorder. Pathological hallmarks of PD are characterized by the presence of α-synuclein…”
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