Search Results - "Singh, Preet Mohinder"

2,4-Diarylpyrano[3,2-c]chromen-5(4H)-ones as Antiproliferative Agents: Design, Synthesis and Biological Evaluation by Kumar, Dinesh, Malik, Fayaz, Bedi, Preet Mohinder Singh, Jain, Subheet

“…In the present study, a series of 2,4-diarylpyrano[3,2-c]chromen-5(4H)-ones were synthesised and evaluated as antiproliferative agents. The compounds were…”
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Recent Developments in 1,2,3‐Triazole Based α‐Glucosidase Inhibitors: Design Strategies, Structure‐Activity Relationship and Mechanistic Insights by Singh, Atamjit, Singh, Karanvir, Sharma, Aman, Kaur, Uttam, Kaur, Kamaljit, Mohinder Singh Bedi, Preet

“…Diabetes mellitus is a chronic and most prevalent metabolic disorder affecting 422 million the people worldwide and causing life‐threatening associated…”
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Role of Cilostazol in Prevention of Vasospasm After Aneurysmal Subarachnoid Hemorrhage–A Systematic Review, Meta-Analysis, and Trial Sequential Analysis by Bohara, Sandeep, Garg, Kanwaljeet, Singh Rajpal, Preet Mohinder, Kasliwal, Manish

“…Cerebral vasospasm is a common complication after aneurysmal subarachnoid hemorrhage (aSAH). Many drugs have been tried to mitigate cerebral vasospasm and…”
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Past, present and future of xanthine oxidase inhibitors: design strategies, structural and pharmacological insights, patents and clinical trials by Singh, Atamjit, Singh, Karanvir, Sharma, Aman, Kaur, Kirandeep, Chadha, Renu, Singh Bedi, Preet Mohinder

“…Xanthine oxidase, a molybdo-flavoenzyme, and an isoform of xanthine dehydrogenase both exist as xanthine oxidoreductase and are responsible for purine…”
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1,2,3‐Triazole Derivatives as an Emerging Scaffold for Antifungal Drug Development against Candida albicans: A Comprehensive Review by Singh, Atamjit, Singh, Karanvir, Sharma, Aman, Joshi, Kaustubh, Singh, Brahmjeet, Sharma, Sambhav, Batra, Kevin, Kaur, Kirandeep, Singh, Dilpreet, Chadha, Renu, Mohinder Singh Bedi, Preet

“…Candida infections are most prominent among fungal infections majorly target immunocompromised and hospitalized patients and cause significant morbidity and…”
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Design, Synthesis, Antimicrobial Evaluation, and Molecular Modeling Studies of Novel Indolinedione–Coumarin Molecular Hybrids by Bhagat, Kavita, Bhagat, Jyoti, Gupta, Manish Kumar, Singh, Jatinder Vir, Gulati, Harmandeep Kaur, Singh, Atamjit, Kaur, Kamalpreet, Kaur, Gurinder, Sharma, Shally, Rana, Abhineet, Singh, Harbinder, Sharma, Sahil, Singh Bedi, Preet Mohinder

“…Keeping in view various pharmacological attributes of indole and coumarin derivatives, a new series of indolindione–coumarin molecular hybrids was rationally…”
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Design and Synthesis of Aza-Flavones as a New Class of Xanthine Oxidase Inhibitors by Dhiman, Rajni, Sharma, Sahil, Singh, Gagandip, Nepali, Kunal, Singh Bedi, Preet Mohinder

“…In an attempt to develop non‐purine‐based xanthine oxidase (XO) inhibitors, keeping in view the complications reported with the use of purine‐based XO…”
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Thiazolidinone Constraint Combretastatin Analogs as Novel Antitubulin Agents: Design, Synthesis, Biological Evaluation and Docking Studies by Sharma, Sahil, Gupta, Manish Kumar, Saxena, Ajit Kumar, Bedi, Preet Mohinder Singh

“…Microtubules act as a useful and strategic molecular target for various anticancer drugs that binds to its distinct sites in tubulin subunits and inhibits its…”
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Protective effect of Grewia asiatica leaves extract in animal models of epilepsy and anxiety by Kaur, Shabnampreet, Singh, Atamjit, Singh, Hasandeep, Singh Bedi, Preet Mohinder, Nepali, Kunal, Singh, Balbir, Kaur, Sarabjit

“…Grewia asiatica Linn. is a well-known plant for its nutritional and therapeutic attributes. It has been mentioned in ancient Indian literature as Rasayana due…”
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Estradiol attenuates ischemia reperfusion-induced acute kidney injury through PPAR-γ stimulated eNOS activation in rats by Singh, Amrit Pal, Singh, Nirmal, Pathak, Devendra, Bedi, Preet Mohinder Singh

“…We investigated the involvement of peroxisome proliferator activated receptor-γ (PPAR-γ)/endothelial nitric oxide synthase (eNOS) pathway in estradiol mediated…”
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Estrogen Attenuates Renal IRI through PPAR-γ Agonism in Rats by Singh, Amrit Pal, M. Pharm, Singh, Nirmal, M. Pharm., PhD, Singh Bedi, Preet Mohinder, M. Pharm., PhD

“…Abstract Background Estrogen is reported to be renoprotective agent in various preclinical studies, attributing to its anti-oxidant and anti-inflammatory…”
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Thiophene derivatives: A potent multitargeted pharmacological scaffold by Singh, Atamjit, Singh, Gurvinder, Bedi, Preet Mohinder Singh

“…Despite a significant work that has been done on thiophene, continuous efforts are still being made by the researchers to identify novel heterocyclic compounds…”
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Microwave-assisted synthesis of 11-substituted-3,3-dimethyl-2,3,4,5,10,11-hexahydrodibenzo[b,e][1,4]diazepin-1-one derivatives catalysed by silica supported fluoroboric acid as potent antioxidant and anxiolytic agents by Bhagat, Kavita, Singh, Atamjit, Dhiman, Suruchi, Vir Singh, Jatinder, Kaur, Ramandeep, Kaur, Gurinder, Kaur Gulati, Harmandeep, Singh, Palwinder, Kumar, Raman, Salwan, Rajan, Bhagat, Kajal, Singh, Harbinder, Sharma, Sahil, Singh Bedi, Preet Mohinder

“…Keeping in view the successive attributes of benzodiazepines on the central nervous system, we have synthesized a novel series of benzodiazepine derivatives as…”
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Design, synthesis, and biological evaluation of novel morpholinated isatin–quinoline hybrids as potent anti‐breast cancer agents by Singh, Atamjit, Kaur, Harneetpal, Arora, Saroj, Bedi, Preet Mohinder Singh

“…Keeping in view the emerging need for potent and safer anti‐breast cancer agents as well as the pharmacological attributes of isatin, quinolone, and morpholine…”
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Xanthine oxidase inhibitors: patent landscape and clinical development (2015-2020) by Singh, Jatinder Vir, Bedi, Preet Mohinder Singh, Singh, Harbinder, Sharma, Sahil

“…Xanthine oxidase (XO) is a molybdoflavoprotein that catalyzes the oxidative hydroxylation of purines to produce uric acid and reactive oxygen species. These…”
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A comprehensive review on thiazole based conjugates as anti-cancer agents by Rana, Rupali, Kumar, Nitish, Gulati, Harmandeep Kaur, Sharma, Anchal, Khanna, Aanchal, Pooja, Badhwar, Rakshit, Dhir, Muskan, Jyoti, Singh, Jatinder Vir, Bedi, Preet Mohinder Singh

“…•Recent developments in synthetic anticancer inhibitors.•Structure activity relationship.•Molecular docking studies.•Future perspective for development of…”
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Pyranoquinolone derivatives: A potent multi‐targeted pharmacological scaffold by Uppal, Jasreen, Mir, Prince Ahad, Chawla, Apporva, Kumar, Nishant, Kaur, Gurinder, Bedi, Preet Mohinder Singh, Bhandari, Divya Dhawal

“…The search for new heterocyclic compounds with potential bioactivities continues despite the fact that extensive work has already been done on…”
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Triazole derivatives as potential xanthine oxidase inhibitors: Design, enzyme inhibition potential, and docking studies by Gulati, Harmandeep Kaur, Khanna, Aanchal, Kumar, Nitish, Sharma, Anchal, Rupali, Jyoti, Singh, Jatindervir, Bhagat, Kavita, Bedi, Preet Mohinder Singh

“…Considerable ingenuity has been shown in the recent years in the discovery of novel xanthine oxidase (XO) inhibitors that fall outside the purine scaffold. The…”
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Recent developments in synthetic strategies and pharmacological outcomes of synthetic xanthine oxidase inhibitors: A comprehensive review by Kaur, Gurinder, Sharma, Rajiv, Ashu, Arora, Geetakshi, Singh, Atamjit, Bedi, Preet Mohinder Singh, Bora, Kundan Singh

“…Abstract Xanthine oxidase is an important enzyme in purine metabolism that converts hypoxanthine to xanthine and subsequently xanthine to uric acid. Its…”
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Pioglitazone ameliorates renal ischemia reperfusion injury through NMDA receptor antagonism in rats by Singh, Amrit Pal, Singh, Nirmal, Bedi, Preet Mohinder Singh

“…The present study investigated the role of N -methyl- d -aspartate (NMDA) receptors in pioglitazone-mediated protection against renal ischemia reperfusion…”
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