Search Results - "Singh, Parmit Kumar"

Host and viral determinants for MxB restriction of HIV-1 infection by Matreyek, Kenneth A, Wang, Weifeng, Serrao, Erik, Singh, Parmit Kumar, Levin, Henry L, Engelman, Alan

“…Interferon-induced cellular proteins play important roles in the host response against viral infection. The Mx family of dynamin-like GTPases, which include…”
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Spatial and Genomic Correlates of HIV-1 Integration Site Targeting by Singh, Parmit Kumar, Bedwell, Gregory J, Engelman, Alan N

“…HIV-1 integrase and capsid proteins interact with host proteins to direct preintegration complexes to active transcription units within gene-dense regions of…”
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Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors by Singh, Parmit Kumar, Li, Wen, Bedwell, Gregory J, Fadel, Hind J, Poeschla, Eric M, Engelman, Alan N

“…Allosteric integrase (IN) inhibitors (ALLINIs), which are promising preclinical compounds that engage the lens epithelium-derived growth factor (LEDGF)/p75…”
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Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration by Zhang, Qiong, Wang, Shaobo, Li, Wanyu, Yau, Edwin, Hui, Hui, Singh, Parmit Kumar, Achuthan, Vasudevan, Young Karris, Maile Ann, Engelman, Alan N, Rana, Tariq M

“…Abstract The retrovirus human immunodeficiency virus-1 (HIV-1) is the causative agent of AIDS. Although treatment of HIV/AIDS with antiretroviral therapy…”
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LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes by Singh, Parmit Kumar, Plumb, Matthew R, Ferris, Andrea L, Iben, James R, Wu, Xiaolin, Fadel, Hind J, Luke, Brian T, Esnault, Caroline, Poeschla, Eric M, Hughes, Stephen H, Kvaratskhelia, Mamuka, Levin, Henry L

“…The host chromatin-binding factor LEDGF/p75 interacts with HIV-1 integrase and directs integration to active transcription units. To understand how LEDGF/p75…”
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A long terminal repeat retrotransposon of Schizosaccharomyces japonicus integrates upstream of RNA pol III transcribed genes by Guo, Yabin, Singh, Parmit Kumar, Levin, Henry L

“…Transposable elements (TEs) are common constituents of centromeres. However, it is not known what causes this relationship. Schizosaccharomyces japonicus…”
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Structural insights into biosynthesis of resorcinolic lipids by a type III polyketide synthase in Neurospora crassa by Goyal, Aneesh, Saxena, Priti, Rahman, Ataur, Singh, Parmit Kumar, Kasbekar, Durgadas P., Gokhale, Rajesh S., Sankaranarayanan, Rajan

“…Microbial type III polyketide synthases (PKSs) have revealed remarkable mechanistic as well as functional versatility. Recently, a type III PKS homolog from…”
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Mobile genetic elements and genome evolution 2014 by Singh, Parmit Kumar, Bourque, Guillaume, Craig, Nancy L, Dubnau, Josh T, Feschotte, Cédric, Flasch, Diane A, Gunderson, Kevin L, Malik, Harmit Singh, Moran, John V, Peters, Joseph E, Slotkin, R Keith, Levin, Henry L

“…The Mobile Genetic Elements and Genome Evolution conference was hosted by Keystone Symposia in Santa Fe, NM USA, 9 March through 14 March 2014. The goal of…”
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Mobile genetic elements and genome evolution 2014 by Singh, Parmit Kumar, Bourque, Guillaume, Craig, Nancy L, Dubnau, Josh T, Feschotte, Cédric, Flasch, Diane A, Gunderson, Kevin L, Malik, Harmit Singh, Moran, John V, Peters, Joseph E, Slotkin, R Keith, Levin, Henry L

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