Search Results - "Singh, Nitu"
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1
α-Synuclein aggregation nucleates through liquid–liquid phase separation
Published in Nature chemistry (01-08-2020)“…α-Synuclein (α-Syn) aggregation and amyloid formation is directly linked with Parkinson’s disease pathogenesis. However, the early events involved in this…”
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2
Molecular basis of death effector domain chain assembly and its role in caspase‐8 activation
Published in The FASEB journal (01-01-2016)“…ABSTRACT Assembly of a death‐inducing signaling complex is a key event in the extrinsic apoptotic pathway, enabling activation of the caspase cascade and…”
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3
Estimation of swelling characteristics of expansive soils with influence of clay mineralogy
Published in Acta agriculturae Scandinavica. Section B, Soil and plant science (03-04-2021)“…In the present study, characterisation and quantitative microanalysis were identified for six expansive soils of which one is natural soil, i.e. black cotton…”
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Carbon coated Cu2O/CuO nanowire photocathodes for enhanced photoelectrochemical water splitting performance
Published in Indian chemical engineer (Calcutta, India : 1997) (03-05-2024)“…We herein report the fabrication of mixed oxide Cu 2 O/CuO nanowire electrodes through the anodisation of Cu-mesh. These synthesised electrodes are then coated…”
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5
7D, a small molecule inhibits dengue infection by increasing interferons and neutralizing-antibodies via CXCL4:CXCR3:p38:IRF3 and Sirt1:STAT3 axes respectively
Published in EMBO molecular medicine (14-10-2024)“…There are a limited number of effective vaccines against dengue virus (DENV) and significant efforts are being made to develop potent anti-virals. Previously,…”
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6
Comparing Audiological Outcomes of Conventional and AI-Upgraded Cochlear Implant Speech Processors
Published in Indian journal of otolaryngology, and head, and neck surgery (01-10-2024)“…In current age of technology, artificial intelligence is used in the medical field to improve the quality and accuracy in patient care and achieve better…”
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Recurrence of tuberculosis among newly diagnosed sputum positive pulmonary tuberculosis patients treated under the Revised National Tuberculosis Control Programme, India: A multi-centric prospective study
Published in PloS one (06-07-2018)“…There is lack of information on the proportion of new smear-positive pulmonary tuberculosis (PTB) patients treated with a 6-month thrice-weekly regimen under…”
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8
Knowledge on child rights among private and government school teachers, Pokhara, Kaski district
Published in Journal of Gandaki Medical College (Print) (31-12-2022)“…Introduction: Children play vital role to the nation’s present and its future. The healthy and educated child of today is the intelligent and active citizen of…”
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Comparative Study of Cardiac Risk Indices to Predict Perioperative Cardiovascular Outcome in Patients with Peripheral Vascular Diseases
Published in Indian journal of vascular and endovascular surgery (01-10-2022)“…Introduction: Existing methodologies and risk stratification indices for predicting peri-operative cardiac complications in vascular surgery patient lack…”
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10
Study of the isothermal equation of state and elastic properties for hcp-transition metals at high pressure
Published in Chemical physics impact (01-06-2024)“…A theoretical model of the equation of state based on Eulerian finite theory for high pressure has recently been reported by Singh et al. The adopted model…”
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11
Immunohistochemical Expression of p16 and p53 as Prognostic Indicator in Oral Squamous Cell Carcinoma: A Cross-sectional Study
Published in Journal of clinical and diagnostic research (01-09-2023)“…Introduction: Head and Neck Squamous Cell Carcinoma (HNSCC) is the sixth most common cancer globally and the seventh most common cause of cancer-related…”
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12
Allosteric regulation of serine protease HtrA2 through novel non-canonical substrate binding pocket
Published in PloS one (14-02-2013)“…HtrA2, a trimeric proapoptotic serine protease is involved in several diseases including cancer and neurodegenerative disorders. Its unique ability to mediate…”
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13
Tactical combat casualty and critical care-An evolving concept in casualty management in a Tertiary Care Hospital
Published in Journal of Marine Medical Society (01-07-2017)“…Introduction: The Indian Army has been in engaged in wars, counter terrorism operations and relief work during natural or manmade disasters for a long time. An…”
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14
Recent developments in Schiff base centered optical and chemical sensors for metal ion recognition
Published in Journal of molecular liquids (01-05-2024)“…[Display omitted] •In this review article, we summarized recent Schiff base sensors (2019–2023) used as fluorimetric or colorimetric sensors for metal ions…”
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15
Effect of Permeation Enhancer on Bioavailability of Formulated Patches of Glibenclamide
Published in International Journal of Pharmaceutical Investigation (16-07-2021)Get full text
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Synthesis, structural elucidation, and antibacterial activities of novel copper(II), cobalt(II), and nickel(II) complexes with a bidentate Schiff base ligand against pathogenic bacteria
Published in Journal of molecular structure (05-02-2025)“…•Synthesis of Cu(II), Co(II) and Ni(II) complexes of novel Schiff base ligand.•Computational calculations for the proposed structures were conducted using…”
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17
Assess the Psychological General Well-Being among Adolescent with Obesity in Selected Schools at Pokhara: A Descriptive Study
Published in Journal of universal college of medical sciences (31-12-2023)“…INTRODUCTION Childhood Obesity, is a serious medical condition that affects children and adolescents whose BMI at or above the 95th percen- tile for children…”
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Role of conserved regulatory loop residues in allosteric propagation of serine protease HtrA2
Published in Biochemical and biophysical research communications (26-02-2022)“…High temperature requirement protease A2 (HtrA2) is a mitochondrial serine protease that demonstrates multifaceted roles including protein quality control and…”
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Corrigendum to “Role of conserved regulatory loop residues in allosteric propagation of serine protease HtrA2”
Published in Biochemical and biophysical research communications (02-04-2022)Get full text
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20
The structural basis of mode of activation and functional diversity: A case study with HtrA family of serine proteases
Published in Archives of biochemistry and biophysics (15-12-2011)“…► HtrAs are protein quality control proteases conserved from prokaryotes to humans. ► HtrA proteins are stable trimers but usually form higher order oligomers…”
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