Search Results - "Singh, Mohini"
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EMT: Mechanisms and therapeutic implications
Published in Pharmacology & therapeutics (Oxford) (01-02-2018)“…Metastasis, the dissemination of cancer cells from primary tumors, represents a major hurdle in the treatment of cancer. The epithelial-mesenchymal transition…”
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The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma
Published in Cell stem cell (04-06-2020)“…CD133 marks self-renewing cancer stem cells (CSCs) in a variety of solid tumors, and CD133+ tumor-initiating cells are known markers of chemo- and…”
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Emerging Immunotherapies in the Treatment of Brain Metastases
Published in The oncologist (Dayton, Ohio) (01-03-2021)“…Brain metastases account for considerable morbidity and mortality in patients with cancer. Despite increasing prevalence, limited therapeutic options exist…”
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Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma
Published in Cancer research (Chicago, Ill.) (01-09-2018)“…Glioblastoma (GBM) carries a dismal prognosis and inevitably relapses despite aggressive therapy. Many members of the Eph receptor tyrosine kinase (EphR)…”
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Nanodiamond Mediated Molecular Targeting in Pancreatic Ductal Adenocarcinoma: Disrupting the Tumor-stromal Cross-talk, Next Hope on the Horizon?
Published in Current cancer drug targets (01-01-2023)“…Pancreatic ductal adenocarcinoma (PDAC) is one of the foremost causes of cancer-related morbidities worldwide. Novel nanotechnology-backed drug delivery…”
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Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor-Initiating Cells
Published in Clinical cancer research (01-12-2015)“…Clonal evolution of cancer may be regulated by determinants of stemness, specifically self-renewal, and current therapies have not considered how genetic…”
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Self-incompatibility: a targeted, unexplored pre-fertilization barrier in flower crops of Asteraceae
Published in Journal of plant research (01-09-2023)“…Asteraceae (synonym as Compositae) is one of the largest angiosperm families among flowering plants comprising one-tenth of all agri-horticultural species…”
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A Study of Arrhythmias in First 48 Hours of Acute Myocardial Infarction in a Tertiary Care Hospital
Published in Journal of clinical and diagnostic research (01-05-2020)“…Introduction: Myocardial infarction is defined as a clinical or pathologic event caused by myocardial ischemia in which there is evidence of myocardial injury…”
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Enhanced efficacy of β-carotene loaded solid lipid nanoparticles optimized and developed via central composite design on breast cancer cell lines
Published in Heliyon (15-04-2024)“…β-carotene is obtained from both plants and animals and has been the subject of intense research because of its provitamin-A, antioxidant, and anticancer…”
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Intercalation vs Adsorption Strategies of Myo-Inositol Hexakisphosphate into Zn–Fe Layered Double Hydroxide: A Tiff between Anion Exchange and Coprecipitation
Published in ACS omega (14-11-2023)“…Myo-inositol hexakisphosphates (IHPs) or phytates are the most abundant organic phosphates having the potential to serve as a phosphorus reserve in soil…”
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Brain metastasis-initiating cells: survival of the fittest
Published in International journal of molecular sciences (22-05-2014)“…Brain metastases (BMs) are the most common brain tumor in adults, developing in about 10% of adult cancer patients. It is not the incidence of BM that is…”
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Molecular and genetic analysis of defensive responses of Brassica juncea – B. fruticulosa introgression lines to Sclerotinia infection
Published in Scientific reports (19-11-2019)“…Sclerotinia stem rot caused by Sclerotinia sclerotiorum is a major disease of crop brassicas, with inadequate variation for resistance in primary gene pools…”
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Preclinical Modeling and Therapeutic Avenues for Cancer Metastasis to the Central Nervous System
Published in Frontiers in oncology (19-09-2017)“…Metastasis is the dissemination of cells from the primary tumor to other locations within the body, and continues to be the predominant cause of death among…”
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Genome wide association analyses to understand genetic basis of flowering and plant height under three levels of nitrogen application in Brassica juncea (L.) Czern & Coss
Published in Scientific reports (19-02-2021)“…Timely transition to flowering, maturity and plant height are important for agronomic adaptation and productivity of Indian mustard ( B. juncea ), which is a…”
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Meta-QTL Analysis in Rice and Cross-Genome Talk of the Genomic Regions Controlling Nitrogen Use Efficiency in Cereal Crops Revealing Phylogenetic Relationship
Published in Frontiers in genetics (21-12-2021)“…The phenomenal increase in the use of nitrogenous fertilizers coupled with poor nitrogen use efficiency is among the most important threats to the environment,…”
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Investigation of FGFR2-IIIC signaling via FGF-2 ligand for advancing GCT stromal cell differentiation
Published in PloS one (11-10-2012)“…Giant cell tumor of bone (GCT) is an aggressive bone tumor consisting of multinucleated osteoclast-like giant cells and proliferating osteoblast-like stromal…”
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Detection of First Marker Trait Associations for Resistance Against Sclerotinia sclerotiorum in Brassica juncea - Erucastrum cardaminoides Introgression Lines
Published in Frontiers in plant science (06-08-2019)“…A set of 96 - introgression lines (ILs) were developed with genomic regions associated with stem rot ( ) resistance from a wild species . ILs were assessed for…”
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Unravelling the genetic framework associated with grain quality and yield-related traits in maize ( Zea mays L.)
Published in Frontiers in genetics (07-08-2023)“…Maize serves as a crucial nutrient reservoir for a significant portion of the global population. However, to effectively address the growing world population's…”
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Corrigendum: Unravelling the genetic framework associated with grain quality and yield-related traits in maize (Zea mays L.)
Published in Frontiers in genetics (12-12-2023)“…[This corrects the article DOI: 10.3389/fgene.2023.1248697.]…”
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