Search Results - "Singh, Manvendra"
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A Single-Cell RNA Expression Map of Human Coronavirus Entry Factors
Published in Cell reports (Cambridge) (22-09-2020)“…To predict the tropism of human coronaviruses, we profile 28 SARS-CoV-2 and coronavirus-associated receptors and factors (SCARFs) using single-cell…”
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2
YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction
Published in PLoS biology (02-12-2020)“…Adverse cardiac remodeling after myocardial infarction (MI) causes structural and functional changes in the heart leading to heart failure. The initial post-MI…”
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3
PDGFRα⁺ pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (03-04-2018)“…Wnts and R-spondins (RSPOs) support intestinal homeostasis by regulating crypt cell proliferation and differentiation. Ex vivo, Wnts secreted by Paneth cells…”
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4
Semaphorin Signaling in Cardiovascular Development
Published in Cell metabolism (03-02-2015)“…Semaphorins were originally identified as neuronal guidance molecules mediating their attractive or repulsive signals by forming complexes with plexin and…”
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Distinct Compartments of the Proepicardial Organ Give Rise to Coronary Vascular Endothelial Cells
Published in Developmental cell (13-03-2012)“…The proepicardial organ is an important transient structure that contributes cells to various cardiac lineages. However, its contribution to the coronary…”
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Emerging roles of the Hippo signaling pathway in modulating immune response and inflammation‐driven tissue repair and remodeling
Published in The FEBS journal (01-07-2022)“…Inflammation is an evolutionarily conserved process and part of the body's defense mechanism. Inflammation leads to the activation of immune and non‐immune…”
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7
Loss of Yap/Taz in cardiac fibroblasts attenuates adverse remodelling and improves cardiac function
Published in Cardiovascular research (22-06-2022)“…Abstract Aims Fibrosis is associated with all forms of adult cardiac diseases including myocardial infarction (MI). In response to MI, the heart undergoes…”
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8
Critical role of the BAF chromatin remodeling complex during murine neural crest development
Published in PLoS genetics (22-03-2021)“…The BAF complex plays an important role in the development of a wide range of tissues by modulating gene expression programs at the chromatin level. However,…”
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New Insights into Hippo/YAP Signaling in Fibrotic Diseases
Published in Cells (Basel, Switzerland) (29-06-2022)“…Fibrosis results from defective wound healing processes often seen after chronic injury and/or inflammation in a range of organs. Progressive fibrotic events…”
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10
Train Length and Service Frequency Optimization: Passenger Health Expense Perspective
Published in International journal of ITS research (01-08-2024)“…The urban transport rail network is represented by operational lines and associated variables such as the origin/destination matrix, ridership, and speed. In…”
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11
Enhancement in the Performance of a-Si:H Thin-Film Solar Cells by Light Trapping from Plasmonic Back Reflector
Published in Plasmonics (Norwell, Mass.) (2024)“…Light trapping is a very essential part of thin-film solar cells to improve their performance and make them comparable to the conventional c-Si solar cells. In…”
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12
The Hippo Signaling Pathway in Cardiac Development and Diseases
Published in Frontiers in cell and developmental biology (01-10-2019)“…Heart disease continues to be the leading cause of morbidity and mortality worldwide. Cardiac malformation during development could lead to embryonic or…”
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13
Vitamin B 12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation
Published in Journal of hepatology (01-11-2022)“…Several recent clinical studies have shown that serum homocysteine (Hcy) levels are positively correlated, while vitamin B (B ) and folate levels are negative…”
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14
Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction
Published in The Journal of clinical investigation (01-03-2017)“…Ischemic heart disease resulting from myocardial infarction (MI) is the most prevalent form of heart disease in the United States. Post-MI cardiac remodeling…”
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15
Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development
Published in Cell reports (Cambridge) (17-05-2016)“…Formation of the coronary vasculature is a complex and precisely coordinated morphogenetic process that begins with the formation of epicardium. The epicardium…”
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16
Mosaic cis-regulatory evolution drives transcriptional partitioning of HERVH endogenous retrovirus in the human embryo
Published in eLife (18-02-2022)“…The human endogenous retrovirus type-H (HERVH) family is expressed in the preimplantation embryo. A subset of these elements are specifically transcribed in…”
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17
Metamaterial-Inspired Complementary Split Ring Resonator Sensor and Second-Order Approximation for Dielectric Characterization of Fluid
Published in Journal of electronic materials (01-10-2021)“…A metamaterial-based complementary split ring resonator (CSRR) structure is used to develop a sensor for dielectric characterization of fluids. The fluid…”
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18
Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos
Published in Blood (13-09-2012)“…The lymphatic vasculature preserves tissue fluid balance by absorbing fluid and macromolecules and transporting them to the blood vessels for circulation. The…”
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19
Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation
Published in Journal of hepatology (01-11-2022)“…Several recent clinical studies have shown that serum homocysteine (Hcy) levels are positively correlated, while vitamin B12 (B12) and folate levels are…”
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20
Semaphorin-PlexinD1 Signaling Limits Angiogenic Potential via the VEGF Decoy Receptor sFlt1
Published in Developmental cell (16-08-2011)“…Sprouting angiogenesis expands the embryonic vasculature enabling survival and homeostasis. Yet how the angiogenic capacity to form sprouts is allocated among…”
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