Search Results - "Singh, Krishn Pratap"

Deciphering the interplay between cysteine synthase and thiol cascade proteins in modulating Amphotericin B resistance and survival of Leishmania donovani under oxidative stress by Singh, Kuljit, Ali, Vahab, Pratap Singh, Krishn, Gupta, Parool, Suman, Shashi S, Ghosh, Ayan K, Bimal, Sanjiva, Pandey, Krishna, Das, Pradeep

“…Leishmania donovani is the causative organism of the neglected human disease known as visceral leishmaniasis which is often fatal, if left untreated. The…”
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Reactive oxygen species regulates expression of iron–sulfur cluster assembly protein IscS of Leishmania donovani by Pratap Singh, Krishn, Zaidi, Amir, Anwar, Shadab, Bimal, Sanjeev, Das, Pradeep, Ali, Vahab

“…The cysteine desulfurase, IscS, is a highly conserved and essential component of the mitochondrial iron–sulfur cluster (ISC) system that serves as a sulfur…”
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Intracellular zinc flux causes reactive oxygen species mediated mitochondrial dysfunction leading to cell death in Leishmania donovani by Kumari, Anjali, Singh, Krishn Pratap, Mandal, Abhishek, Paswan, Ranjeet Kumar, Sinha, Preeti, Das, Pradeep, Ali, Vahab, Bimal, Sanjiva, Lal, Chandra Shekhar

“…Leishmaniasis caused by Leishmania parasite is a global threat to public health and one of the most neglected tropical diseases. Therefore, the discovery of…”
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Stage-dependent expression and up-regulation of trypanothione synthetase in amphotericin B resistant Leishmania donovani by Equbal, Asif, Suman, Shashi Shekhar, Anwar, Shadab, Singh, Krishn Pratap, Zaidi, Amir, Sardar, Abul Hasan, Das, Pradeep, Ali, Vahab

“…Kinetoplastids differ from other organisms in their ability to conjugate glutathione and spermidine to form trypanothione which is involved in maintaining…”
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Maternal and severe anaemia in delivering women is associated with risk of preterm and low birth weight: A cross sectional study from Jharkhand, India by Kumari, Shweta, Garg, Neelima, Kumar, Amod, Guru, Pawas Kumar Indra, Ansari, Sharafat, Anwar, Shadab, Singh, Krishn Pratap, Kumari, Priti, Mishra, Prashant Kumar, Gupta, Birendra Kumar, Nehar, Shamshun, Sharma, Ajay Kumar, Raziuddin, Mohammad, Sohail, Mohammad

“…Haemoglobin content is the well accepted indicator for anaemia assessment. The high prevalence of anaemia, maternal health care issues and adverse delivery…”
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iNOS polymorphism modulates iNOS/NO expression via impaired antioxidant and ROS content in P. vivax and P. falciparum infection by Kumar, Amod, Singh, Krishn Pratap, Bali, Prerna, Anwar, Shadab, Kaul, Asha, Singh, Om P., Gupta, Birendra Kumar, Kumari, Nutan, Noor Alam, Md, Raziuddin, Mohammad, Sinha, Manoranjan Prasad, Gourinath, Samudrala, Sharma, Ajay Kumar, Sohail, Mohammad

“…Nitric oxide (NO) has dicotomic influence on modulating host-parasite interplay, synchronizing physiological orchestrations and diagnostic potential;…”
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Interaction between Nbp35 and Cfd1 proteins of cytosolic Fe-S cluster assembly reveals a stable complex formation in Entamoeba histolytica by Anwar, Shadab, Dikhit, Manas Ranjan, Singh, Krishn Pratap, Kar, Rajiv Kumar, Zaidi, Amir, Sahoo, Ganesh Chandra, Roy, Awadh Kishore, Nozaki, Tomoyoshi, Das, Pradeep, Ali, Vahab

“…Iron-Sulfur (Fe-S) proteins are involved in many biological functions such as electron transport, photosynthesis, regulation of gene expression and enzymatic…”
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Leishmania and its quest for iron: An update and overview by Zaidi, Amir, Singh, Krishn Pratap, Ali, Vahab

“…•Leishmania depends upon host for the source of iron which plays crucial role of the parasite survival.•Iron transporter provides sufficient iron for growth…”
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Detection and functional characterization of sigma class GST in Phlebotomus argentipes and its role in stress tolerance and DDT resistance by Hassan, Faizan, Singh, Krishn Pratap, Ali, Vahab, Behera, Sachidananda, Shivam, Pushkar, Das, Pradeep, Dinesh, Diwakar Singh

“…Several Glutathione S-transferases (GSTs) enzymes, in insects, have previously been implicated in resistance developed against DDT and other insecticides. The…”
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Amplification and Characterization of DDT Metabolizing Delta Class GST in Sand Fly, Phlebotomus argentipes (Diptera: Psychodidae) From Bihar, India by Hassan, Faizan, Singh, Krishn Pratap, Shivam, Pushkar, Ali, Vahab, Dinesh, Diwakar Singh

“…Phlebotomus argentipes is an established vector for Visceral leishmaniasis prevalent in the Indian subcontinent. Insect Glutathione S-transferases (GST) enzyme…”
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LdIscU is a [2Fe-2S] scaffold protein which interacts with LdIscS and its expression is modulated by Fe-S proteins in Leishmania donovani by Singh, Krishn Pratap, Anwar, Shadab, Zaidi, Amir, Singh, Kuljit, Das, Pradeep, Gourinath, Samudrala, Ali, Vahab

“…The pathogenicity of protozoan parasites is frequently attributed to their ability to circumvent the deleterious effects of ROS and Fe-S clusters are among…”
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Interaction between cysteine synthase and serine O-acetyltransferase proteins and their stage specific expression in Leishmania donovani by Singh, Kuljit, Singh, Krishn Pratap, Equbal, Asif, Suman, Shashi S., Zaidi, Amir, Garg, Gaurav, Pandey, Krishna, Das, Pradeep, Ali, Vahab

“…Leishmania possess a unique trypanothione redox metabolism with undebated roles in protection from oxidative damage and drug resistance. The biosynthesis of…”
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Cytosolic tryparedoxin of Leishmania donovani modulates host immune response in visceral leishmaniasis by Suman, Shashi Shekhar, Amit, Ajay, Singh, Krishn Pratap, Gupta, Parool, Equbal, Asif, Kumari, Arti, Topno, Roshan Kamal, Ravidas, Vidyananda, Pandey, Krishna, Bimal, Sanjiva, Das, Pradeep, Ali, Vahab

“…•Cytosolic tryparedoxin (cTXN) is a crucial oxidoreductase protein of thiol metabolic cascade.•cTXN protein supplementation enhances in vitro growth rate of L…”
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Up-regulation of cytosolic tryparedoxin in Amp B resistant isolates of Leishmania donovani and its interaction with cytosolic tryparedoxin peroxidase by Suman, Shashi S., Equbal, Asif, Zaidi, Amir, Ansari, Md. Yousuf, Singh, Krishn Pratap, Singh, Kuljit, Purkait, Bidyut, Sahoo, Ganesh Chandra, Bimal, Sanjeeva, Das, Pradeep, Ali, Vahab

“…Leishmania is a unicellular protozoan parasite which causes leishmaniasis, a neglected tropical disease. It possess a unique thiol metabolism comprising of…”
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Role of IL-1β, IL-6 and TNF-α cytokines and TNF-α promoter variability in Plasmodium vivax infection during pregnancy in endemic population of Jharkhand, India by Singh, Krishn Pratap, Shakeel, Shayan, Naskar, Namrata, Bharti, Aakanksha, Kaul, Asha, Anwar, Shadab, Kumari, Shweta, Kumar, Amod, Singh, Jiv Kant, Kumari, Nutan, Gupta, Birendra Kumar, Manna, Purwa, Roy, Vishwaprakash, Lata, Sneh, Singh, Om P., Sinha, Manoranjan Prasad, Sharma, Ajay Kumar, Sohail, Mohammad

“…•P.vivax infection modulates the circulating concentration of IL-1β, TNF-α and IL-6 during pregnancy.•Inflammatory cytokines response depends on both infection…”
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Prevalence of Malaria Infection and Risk Factors Associated with Anaemia among Pregnant Women in Semiurban Community of Hazaribag, Jharkhand, India by Sharma, Ajay Kumar, Ali, Vahab, Adak, Tridibes, Das, Pradeep, Raziuddin, Mohammad, Islam, Mazahirul, Singh, Krishn Pratap, Anwar, Shadab, Zahid, Faisal, Bharti, Aakanksha, Kumari, Shweta, Shakeel, Shayan, Sohail, Mohammad, Lata, Sneh

“…The escalating burden, pathogenesis, and clinical sequel of malaria during pregnancy have combinatorial adverse impact on both mother and foetus that further…”
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Interaction of frataxin, an iron binding protein, with IscU of Fe–S clusters biogenesis pathway and its upregulation in AmpB resistant Leishmania donovani by Zaidi, Amir, Singh, Krishn Pratap, Anwar, Shadab, Suman, Shashi S., Equbal, Asif, Singh, Kuljit, Dikhit, Manas R., Bimal, Sanjeeva, Pandey, Krishna, Das, Pradeep, Ali, Vahab

“…Leishmania donovani is a unicellular protozoon parasite that causes visceral leishmaniasis (VL), which is a fatal disease if left untreated. Certain Fe–S…”
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Stage-Dependent Expression and Up-Regulation of Trypanothione Synthetase in Amphotericin B Resistant Leishmania donovani: e97600 by Equbal, Asif, Suman, Shashi Shekhar, Anwar, Shadab, Singh, Krishn Pratap, Zaidi, Amir, Sardar, Abul Hasan, Das, Pradeep, Ali, Vahab

“…Kinetoplastids differ from other organisms in their ability to conjugate glutathione and spermidine to form trypanothione which is involved in maintaining…”
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Interaction between Nbp35 and Cfd1 Proteins of Cytosolic Fe-S Cluster Assembly Reveals a Stable Complex Formation in Entamoeba histolytica: e108971 by Anwar, Shadab, Dikhit, Manas Ranjan, Singh, Krishn Pratap, Kar, Rajiv Kumar, Zaidi, Amir, Sahoo, Ganesh Chandra, Roy, Awadh Kishore, Nozaki, Tomoyoshi, Das, Pradeep, Ali, Vahab

“…Iron-Sulfur (Fe-S) proteins are involved in many biological functions such as electron transport, photosynthesis, regulation of gene expression and enzymatic…”
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