Search Results - "Singh, Iqubal"

Synthesis, cytotoxicity, pharmacokinetic profile, binding with DNA and BSA of new imidazo[1,2-a]pyrazine-benzo[d]imidazol-5-yl hybrids by Singh, Iqubal, Luxami, Vijay, Paul, Kamaldeep

“…Novel derivatives possessing imidazo[1,2- a ]pyrazine and 1 H -benzo[ d ]imidazole scaffolds were synthesized using Suzuki-Miyaura cross-coupling reactions. In…”
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Sulphur Containing Heterocyclic Compounds as Anticancer Agents by Kaur, Balwinder, Singh, Gurdeep, Sharma, Vikas, Singh, Iqubal

“…After cardiovascular disease, cancer is the most common cause of death worldwide. Due to their versatility, heterocyclic compounds play an important role in…”
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Pyrrolidine derivatives as α-amylase and α-glucosidase inhibitors: Design, synthesis, structure-activity relationship (SAR), docking studies and HSA binding by Bhat, Aeyaz Ahmad, Tandon, Nitin, Singh, Iqubal

“…In our pursuit of developing effective inhibitors for the enzymes α-amylase and α-glucosidase, which play a crucial role in carbohydrate metabolism related to…”
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Synthesis, characterization and anti-tubercular activities of copper(II) complexes of substituted 2,3-isatin bisthiosemicarbazones: An experimental and theoretical approach by Ain, Qurat Ul, Singh, Amandeep, Singh, Iqubal, Carmieli, Raanan, Sharma, Rekha

“…Square planar complexes of copper(II)- substituted 2,3-isatin bisthiosemicarbazones have shown enhanced anti-TB activity. Experimental data is well supported…”
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Marine-derived Natural Products as Anticancer Agents by Saini, Nancy, Sirohi, Ritika, A, Anuradha, Saini, Neetu, Wadhwa, Pankaj, Kaur, Paranjeet, Sharma, Vikas, Singh, Gurdeep, Singh, Iqubal, Sahu, Sanjeev Kumar

“…Cancer is a deadly human disease on the rise due to changes in lifestyle, nutrition, and global warming. Cancer is characterized by uncontrolled, disordered,…”
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Recent progress in nanomaterial-based aptamers as biosensors for point of care detection of Hg 2+ ions and its environmental applications by Raina, Jeevika, Kaur, Gurdeep, Singh, Iqubal

“…Among the foremost persistent heavy metal ions in the ecosystem, mercury (Hg ) remains intimidating to the environment by producing a catastrophic effect on…”
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Spectroscopy and molecular docking approach for investigation on the binding of nocodazole to human serum albumin by Singh, Iqubal, Luxami, Vijay, Paul, Kamaldeep

“…The interaction between nocodazole (Nz) and human serum albumin (HSA) under controlled physiological condition (pH 7.4) is examined using absorption, emission,…”
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Recent progress in nanomaterial-based aptamers as biosensors for point of care detection of Hg2+ ions and its environmental applications by Raina, Jeevika, Kaur, Gurdeep, Singh, Iqubal

“…Among the foremost persistent heavy metal ions in the ecosystem, mercury (Hg2+) remains intimidating to the environment by producing a catastrophic effect on…”
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A novel naphthalimide-derived “turn-off” chemosensor for the detection of Cu2+, F- and CN- ions by Kaur, Gurdeep, Kumar, Gulshan, Singh, Iqubal

“…•A novel Schiff base was synthesized and prepared for the detection of Cu2+, F-, and CN- ions using CH3CN as the medium.•The chemosensor exhibits a red shift…”
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Structure activity relationship (SAR) and anticancer activity of pyrrolidine derivatives: Recent developments and future prospects (A review) by Bhat, Aeyaz Ahmad, Singh, Iqubal, Tandon, Nitin, Tandon, Runjhun

“…Pyrrolidine molecules are a significant class of synthetic and natural plant metabolites, which show the diversity of pharmacological activities. An extensive…”
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Effective synthesis of benzimidazoles-imidazo[1,2-a]pyrazine conjugates: A comparative study of mono-and bis-benzimidazoles for antitumor activity by Singh, Iqubal, Luxami, Vijay, Paul, Kamaldeep

“…A novel series of 6-substituted-8-(1-cyclohexyl-1H-benzo[d]imidazole-6-yl)imidazo[1,2-a]pyrazine and…”
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Synthesis of naphthalimide-phenanthro[9,10-d]imidazole derivatives: In vitro evaluation, binding interaction with DNA and topoisomerase inhibition by Singh, Iqubal, Luxami, Vijay, Paul, Kamaldeep

“…A series of naphthalimide based phenanthro[9,10-d]imidazole derivatives has been synthesized and screen in vitro biological activity for human cancer cell…”
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Structure-activity relationship (SAR) and antibacterial activity of pyrrolidine based hybrids: A review by Bhat, Aeyaz Ahmad, Tandon, Nitin, Singh, Iqubal, Tandon, Runjhun

“…•The recent progress of pyrrolidine derivatives for antibacterial activity is reviewed.•The corresponding structure-activity relationships are described.•The…”
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Synthesis of 5-(4-(1H-phenanthro[9,10-d]imidazol-2-yl)benzylidene)thiazolidine-2,4-dione as promising DNA and serum albumin-binding agents and evaluation of antitumor activity by Singh, Iqubal, Rani, Richa, Luxami, Vijay, Paul, Kamaldeep

“…A series of phenanthro[9,10-d]imidazole/oxazole and acenaphtho[1,2-d]imidazole with different aryl groups at C2-position has been synthesized. These compounds…”
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Dual-channel ratiometric recognition of Al3+ and F− ions through an ESIPT-ESICT signalling mechanism by Kumar, Gulshan, Singh, Iqubal, Goel, Richa, Paul, Kamaldeep, Luxami, Vijay

“…[Display omitted] •Synthesis of a novel chromo-fluorescent naphthalimide based probe 1.•Probe 1 exhibited dual emission at 510 nm and 610 nm due to ESIPT/ESICT…”
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DNA intercalators as anticancer agents by Venugopal, Sneha, Sharma, Vikas, Mehra, Anuradha, Singh, Iqubal, Singh, Gurdeep

“…Cancer is one of the most prevailing disease conditions, which occurs due to uncontrolled cell division either due to natural mutation to the genes or due to…”
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Recent advancements in coumarin based colorimetric and fluorescent chemosensors by Kaur, Gurdeep, Singh, Iqubal, Tandon, Runjhun, Tandon, Nitin

“…[Display omitted] •The presence of harmful ions in the environment requires detection at even nanoscale level, and chemosensors plays a pivotal role in…”
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Copper(II) complexes of fused ring selenosemicarbazones: Synthesis, structure elucidation, biological activity and molecular modeling by Malhi, Rinku, Singh, Iqubal, Carmieli, Raanan, Savci, Ahmet, Sharma, Rekha

“…[Display omitted] Reaction of copper(II) acetate with cyclohexanoneselenosemicarbazone (Hcysesc), 5-chloro isatinselenosemicarbazone (5-ClHIstsesc), 1-methyl…”
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Synthesis and in vitro evaluation of naphthalimide-benzimidazole conjugates as potential antitumor agents by Singh, Iqubal, Luxami, Vijay, Paul, Kamaldeep

“…A series of novel naphthalimide-benzimidazoles was designed and synthesized for the first time and studied for their effect on antiproliferative activity. Some…”
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Naphthalimide-benzimidazole conjugate towards “Turn-on” recoginition of Hg2+ in pure aqueous medium by Singh, Iqubal, Kumar, Gulshan, Palta, Aastha, luxami, Vijay, Paul, Kamaldeep

“…[Display omitted] •Naphthalimide-benzimidazole conjugate was studied for selective detection of Hg2+ ions in aqueous medium.•Detection of limit was found to be…”
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