Search Results - "Singh, Guy"
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Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye
Published in Proceedings of the National Academy of Sciences - PNAS (03-02-2015)“…Significance Proteins and lipids accumulating in deposits external to the retinal pigment epithelium (RPE) represent a barrier to metabolic exchange between…”
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2
Molecular epidemiology and expression of capsular polysaccharides in Staphylococcus aureus clinical isolates in the United States
Published in PloS one (14-01-2019)“…Staphylococcus aureus capsular polysaccharides (CP) are important virulence factors under evaluation as vaccine antigens. Clinical S. aureus isolates have the…”
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3
Structures of the Muraymycins, Novel Peptidoglycan Biosynthesis Inhibitors
Published in Journal of the American Chemical Society (04-09-2002)“…The muraymycins, a family of nucleoside-lipopeptide antibiotics, were purified from the extract of Streptomyces sp. LL-AA896. The antibiotics were purified by…”
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4
Mechanism of Action of the Mannopeptimycins, a Novel Class of Glycopeptide Antibiotics Active against Vancomycin-Resistant Gram-Positive Bacteria
Published in Antimicrobial Agents and Chemotherapy (01-03-2004)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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5
3,5-Dioxopyrazolidines, Novel Inhibitors of UDP-N- Acetylenolpyruvylglucosamine Reductase (MurB) with Activity against Gram-Positive Bacteria
Published in Antimicrobial Agents and Chemotherapy (01-02-2006)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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6
Naphthyl Tetronic Acids as Multi-Target Inhibitors of Bacterial Peptidoglycan Biosynthesis
Published in ChemMedChem (08-10-2007)“…A pathway screen targeting multiple muramyl peptide synthesis inhibitors identified the naphthyl tetronic acids series. Optimization of this series based on…”
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7
Further Evidence that a Cell Wall Precursor [C55-MurNAc-(Peptide)-GlcNAc] Serves as an Acceptor in a Sorting Reaction
Published in Journal of Bacteriology (01-04-2002)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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8
Use of Ribotyping To Retrospectively Identify Methicillin-Resistant Staphylococcus aureus Isolates from Phase 3 Clinical Trials for Tigecycline That Are Genotypically Related to Community-Associated Isolates
Published in Antimicrobial Agents and Chemotherapy (01-11-2005)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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9
BNT162b vaccines protect rhesus macaques from SARS-CoV-2
Published in Nature (London) (08-04-2021)“…A safe and effective vaccine against COVID-19 is urgently needed in quantities that are sufficient to immunize large populations. Here we report the…”
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10
Pyrazolidine-3,5-diones and 5-Hydroxy-1H-pyrazol-3(2H)-ones, Inhibitors of UDP-N-acetylenolpyruvyl Glucosamine Reductase
Published in Journal of medicinal chemistry (05-10-2006)“…A series of pyrazolidine-3,5-dione and 5-hydroxy-1H-pyrazol-3(2H)-one inhibitors of Escherichia coli UDP-N-acetylenolpyruvyl glucosamine reductase (MurB) has…”
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11
Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye
Published in Proceedings of the National Academy of Sciences - PNAS (20-01-2015)“…Significance Proteins and lipids accumulating in deposits external to the retinal pigment epithelium (RPE) represent a barrier to metabolic exchange between…”
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Journal Article -
12
Pulvinones as bacterial cell wall biosynthesis inhibitors
Published in Bioorganic & medicinal chemistry letters (2006)“…Pulvinones were synthesized (>180) in arrays and evaluated as inhibitors of early stage cell wall biosynthesis enzymes MurA–MurD. Several pulvinones inhibited…”
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13
4-Alkyl and 4,4′-dialkyl 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione derivatives as new inhibitors of bacterial cell wall biosynthesis
Published in Bioorganic & medicinal chemistry letters (16-05-2005)“…An efficient microwave-assisted synthesis of substituted pyrazolidinediones was developed. These compounds showed good activity against MurB and Gram-positive…”
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14
Muraymycins, novel peptidoglycan biosynthesis inhibitors: synthesis and SAR of their analogues
Published in Bioorganic & medicinal chemistry letters (06-10-2003)“…A series of Muraymycin analogues was synthesized. These analogues showed excellent antimicrobial activity against gram-positive organisms. These analogues also…”
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15
Phenyl thiazolyl urea and carbamate derivatives as new inhibitors of bacterial cell-wall biosynthesis
Published in Bioorganic & medicinal chemistry letters (05-01-2004)“…Over 50 phenyl thiazolyl urea and carbamate derivatives were synthesized for evaluation as new inhibitors of bacterial cell-wall biosynthesis. Many of them…”
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16
Muraymycins, novel peptidoglycan biosynthesis inhibitors: semisynthesis and SAR of Their derivatives
Published in Bioorganic & medicinal chemistry letters (02-09-2002)“…Sixteen muraymycin derivatives 2– 17 were synthesized based on selective reactions of the primary and secondary amino groups of muraymycin C1 ( 1) with…”
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17
2-phenyl-5,6-dihydro-2H-thieno[3,2-c]pyrazol-3-ol derivatives as new inhibitors of bacterial cell wall biosynthesis
Published in Bioorganic & medicinal chemistry letters (04-08-2003)“…Twenty-five 2-phenyl-5,6-dihydro-2H-thieno[3,2-c]pyrazol-3-ol derivatives were synthesized for evaluation as new inhibitors of bacterial cell wall…”
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18
Pyrazolidine-3,5-diones and 5-Hydroxy-1 H -pyrazol-3(2 H )-ones, Inhibitors of UDP- N -acetylenolpyruvyl Glucosamine Reductase
Published in Journal of medicinal chemistry (01-10-2006)Get full text
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19
2-Phenyl-5,6-dihydro-2 H-thieno[3,2- c]pyrazol-3-ol derivatives as new inhibitors of bacterial cell wall biosynthesis
Published in Bioorganic & medicinal chemistry letters (2003)“…Twenty-five 2-phenyl-5,6-dihydro-2 H-thieno[3,2- c]pyrazol-3-ol derivatives were synthesized for evaluation as new inhibitors of bacterial cell wall…”
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20
Securing the mobile E-conomy
Published in Wireless Week (15-05-2000)“…The wireless world presents a greater security risk than the wired world, for two reasons: 1. The encryption used in mobile communications is vulnerable. 2. A…”
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