Search Results - "Singh, Brahma N"

Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications by Singh, Brahma N., Shankar, Sharmila, Srivastava, Rakesh K.

“…An expanding body of preclinical evidence suggests EGCG, the major catechin found in green tea (Camellia sinensis), has the potential to impact a variety of…”
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Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells by Singh, Brahma N., Kumar, Dhruv, Shankar, Sharmila, Srivastava, Rakesh K.

“…Regulation of autophagy and apoptosis by rottlerin. ROT can induce autophagy which leads to cell death in pancreatic CSCs. Rottlerin induces conversion of…”
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Product Development, Manufacturing, and Packaging of Solid Dosage Forms Under QbD and PAT Paradigm: DOE Case Studies for Industrial Applications by Singh, Brahma N.

“…An integrated approach based on QbD and PAT provides a systematic and innovative framework for product development, manufacturing, and quality risk management…”
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Hedgehog signaling antagonist GDC-0449 (Vismodegib) inhibits pancreatic cancer stem cell characteristics: molecular mechanisms by Singh, Brahma N, Fu, Junsheng, Srivastava, Rakesh K, Shankar, Sharmila

“…Recent evidence from in vitro and in vivo studies has demonstrated that aberrant reactivation of the Sonic Hedgehog (SHH) signaling pathway regulates genes…”
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Phyllanthus emblica fruit extract stabilized biogenic silver nanoparticles as a growth promoter of wheat varieties by reducing ROS toxicity by Kannaujia, Rekha, Srivastava, Chandra Mohan, Prasad, Vivek, Singh, Brahma N., Pandey, Vivek

“…The present study is focused on the biogenic synthesis of AgNPs (B-AgNPs) using fruit extract of Phyllanthus emblica L. and its effect (0, 5, 10, 25, 50 mg/L…”
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Antioxidant and free radical scavenging activities of phenols from onion ( Allium cepa) by Prakash, Dhan, Singh, Brahma N., Upadhyay, Garima

“…Four (red, violet, white and green) varieties of Allium cepa were studied for their total phenolic contents (TPC), antioxidant (AOA) and free radical…”
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Chrysophanol: A Natural Anthraquinone with Multifaceted Biotherapeutic Potential by Yusuf, Mohd Aslam, Singh, Brahma N, Sudheer, Surya, Kharwar, Ravindra N, Siddiqui, Saba, Abdel-Azeem, Ahmed M, Fernandes Fraceto, Leonardo, Dashora, Kavya, Gupta, Vijai K

“…Chrysophanol is a unique anthraquinone having broad-spectrum therapeutic potential along with ecological importance. It is the first polyketide that has been…”
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Oxidative DNA damage protective activity, antioxidant and anti-quorum sensing potentials of Moringa oleifera by Singh, Brahma N., Singh, B.R., Singh, R.L., Prakash, D., Dhakarey, R., Upadhyay, G., Singh, H.B.

“…The aqueous extract of leaf (LE), fruit (FE) and seed (SE) of Moringa oleifera was assessed to examine the ability to inhibit the oxidative DNA damage,…”
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Scaffold of Selenium Nanovectors and Honey Phytochemicals for Inhibition of Pseudomonas aeruginosa Quorum Sensing and Biofilm Formation by Prateeksha, Singh, Braj R, Shoeb, M, Sharma, S, Naqvi, A H, Gupta, Vijai K, Singh, Brahma N

“…Honey is an excellent source of polyphenolic compounds that are effective in attenuating quorum sensing (QS), a chemical process of cell-to-cell communication…”
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Nonhistone protein acetylation as cancer therapy targets by Singh, Brahma N, Zhang, Guanghua, Hwa, Yi L, Li, Jinping, Dowdy, Sean C, Jiang, Shi-Wen

“…Acetylation and deacetylation are counteracting, post-translational modifications that affect a large number of histone and nonhistone proteins. The…”
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Solid-state cultivation of Trichoderma harzianum NBRI-1055 for modulating natural antioxidants in soybean seed matrix by Singh, Harikesh B., Singh, Brahma N., Singh, Satyendra P., Nautiyal, Chandra S.

“…Trichoderma harzianum NBRI-1055 was used, as fungal candidate to enhance the antioxidant activities of soybean matrix by modulating polyphenolic substances…”
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Potential chemoprevention of N-nitrosodiethylamine-induced hepatocarcinogenesis by polyphenolics from Acacia nilotica bark by Singh, Brahma N., Singh, Braj R., Sarma, B.K., Singh, H.B.

“…Chemopreventive potential of Acacia nilotica bark extract (ANBE) against single intraperitoneal injection of N-nitrosodiethylamine (NDEA, 200 mg/kg) followed…”
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Total phenol, antioxidant and free radical scavenging activities of some medicinal plants by Prakash, Dhan, Suri, Samiksha, Upadhyay, Garima, Singh, Brahma N

“…Phenols, a major group of antioxidant phytochemicals, have profound importance due to their biological and free radical scavenging activities. To identify…”
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Unraveling Compositional Study, Chemometric Analysis, and Cell-Based Antioxidant Potential of Selective High Nutraceutical Value Amaranth Cultivars Using a GC-MS and NMR-Based Metabolomics Approach by Gupta, Annie, Singh, Gaurav Deep, Gautam, Arti, Tripathi, Tusha, Taneja, Amit Kumar, Singh, Brahma N, Roy, Raja, Sidhu, Om P., Panda, Sunil Kumar, Bhatt, Arun

“…Amaranthus (family Amaranthaceae) is a potentially nutritious pseudocereal also known as a functional food owing to its high nutritional quality grains…”
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Cinnamomum verum-derived bioactives-functionalized gold nanoparticles for prevention of obesity through gut microbiota reshaping by Sharma, Vivek K., Prateeksha, Gupta, Sateesh C., Singh, Brahma N., Rao, Chandana V., Barik, Saroj K.

“…Existing drugs have limited success in managing obesity in human due to their low efficacy and severe side-effects. Surface-modified gold nanoparticles have…”
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Ageratum enation virus Infection Induces Programmed Cell Death and Alters Metabolite Biosynthesis in Papaver somniferum by Srivastava, Ashish, Agrawal, Lalit, Raj, Rashmi, Jaidi, Meraj, Raj, Shri K, Gupta, Swati, Dixit, Ritu, Singh, Poonam C, Tripathi, Tusha, Sidhu, Om P, Singh, Brahma N, Shukla, Sudhir, Chauhan, Puneet S, Kumar, Susheel

“…A previously unknown disease which causes severe vein thickening and inward leaf curl was observed in a number of opium poppy ( L.) plants. The sequence…”
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Emerging advances in glycoengineering of carbohydrates/glycans and their industrial applications by Singh, Brahma N., Tabatabaei, Meisam, Pandit, Abhay, Elling, Lothar, Gupta, Vijai Kumar

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Superior inhibition of virulence and biofilm formation of Pseudomonas aeruginosa PAO1 by phyto-synthesized silver nanoparticles through anti-quorum sensing activity by Kumar, Sanket, Paliya, Balwant S., Singh, Brahma N.

“…Quorum sensing (QS)-regulated bacterial biofilm formation is a crucial issue in causing resistance against existing antibiotics. There is a considerable…”
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Non-Toxic and Ultra-Small Biosilver Nanoclusters Trigger Apoptotic Cell Death in Fluconazole-Resistant Candida albicans via Ras Signaling by Singh, Braj Raj, Gupta, Vijai Kumar, Deeba, Farah, Bajpai, Rajesh, Pandey, Vivek, Naqvi, Alim H, Upreti, Dalip Kumar, Gathergood, Nicholas, Jiang, Yueming, El Enshasy, Hesham A, Sholkamy, Essam Nageh, Mostafa, Ashraf A, Hesham, Abd El-Latif, Singh, Brahma N

“…Silver-based nanostructures are suitable for many biomedical applications, but to be useful therapeutic agents, the high toxicity of these nanomaterials must…”
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Mycofabricated biosilver nanoparticles interrupt Pseudomonas aeruginosa quorum sensing systems by Singh, Braj R., Singh, Brahma N., Singh, Akanksha, Khan, Wasi, Naqvi, Alim H., Singh, Harikesh B.

“…Quorum sensing (QS) is a chemical communication process that Pseudomonas aeruginosa uses to regulate virulence and biofilm formation. Disabling of QS is an…”
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