Search Results - "Singer, M.V"

Cyclooxygenase-2 contributes to the selective induction of cell death by the endocannabinoid 2-arachidonoyl glycerol in hepatic stellate cells by Siegmund, S.V., Wojtalla, A., Schlosser, M., Schildberg, F.A., Knolle, P.A., Nüsing, R.M., Zimmer, A., Strassburg, C.P., Singer, M.V.

“…The endogenous cannabinoid 2-arachidonoyl glycerol (2-AG) is an anti-fibrotic lipid mediator that induces apoptosis in hepatic stellate cells (HSCs), but not…”
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395 COX-2 DRIVES THE SELECTIVE INDUCTION OF APOPTOSIS BY THE ENDOCANNABINOID 2-ARACHIDONOYL GLYCEROL IN HEPATIC STELLATE CELLS by Siegmund, S.V, Wojtalla, A, Schlosser, M, Sauerbruch, T, Singer, M.V

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394 THE NOVEL ENDOCANNABINOID NOLADIN ETHER SELECTIVELY INDUCES CELL DEATH IN HEPATIC STELLATE CELLS VIA AN ROS-DEPENDENT MECHANISM by Wojtalla, A, Schlosser, M, Singer, M.V, Sauerbruch, T, Zimmer, A, Siegmund, S

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1134 FATTY ACID AMIDE HYDROLASE IS THE HEPATIC GATEKEEPER AGAINST ENDOCANNABINOID-INDUCED CELL DEATH AND HOLDS ANTI-FIBROTIC PROPERTIES by Schlosser, M, Wojtalla, A, Schildberg, F.A, Knolle, P.A, Sauerbruch, T, Singer, M.V, Zimmer, A, Siegmund, S.V

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985 THE NOVEL ENDOCANNABINOID VIRODHAMINE SELECTIVELY INDUCES CELL DEATH IN HEPATIC STELLATE CELLS by Wojtalla, A, Herweck, F, Singer, M.V, Zimmer, A, Siegmund, S.V

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294 FATTY ACID AMIDE HYDROLASE BUT NOT MONOACYL GLYCEROL LIPASE IS A CRITICAL INHIBITOR OF ENDOCANNABINOID-INDUCED CELL DEATH IN HEPATIC CELL POPULATIONS by Siegmund, S.V, Wojtalla, A, Herweck, F, Singer, M.V

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494 THE ENDOCANNABINOID N-ARACHIDONOYL DOPAMINE (NADA) INDUCES CELL DEATH IN PRIMARY HEPATIC STELLATE CELLS VIA ROS PRODUCTION INDEPENDENTLY OF MEMBRANE CHOLESTEROL OR CANNABINOID-RECEPTORS by Siegmund, S.V, Wojtalla, A, Herweck, F, Singer, M.V

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994 IL-13 INDUCES CTGF EXPRESSION IN RAT HEPATIC STELLATE CELLS VIA ACTIVATING OF SMAD SIGNALING by Liu, Y, Meyer, C, Mueller, A, Herweck, F, Stump, C, Singer, M.V, Dooley, S, Weng, H

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238 TRANSFORMING GROWTH FACTOR (TGF)-β INCREASES THE ADVERSE EFFECTS OF ETHANOL ON HEPATOCYTES: TWO INTERACTING SIGNAL TRANSDUCTION PATHWAYS LEADING TO APOPTOSIS AND FIBROSIS IN THE LIVER by Gaitantzi, H, Ciuclan, L, Godoy, P, Singer, M.V, Dooley, S, Breitkopf, K

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The functional polymorphism -262 C>T in the catalase gene (CAT) but not the polymorphism V16A in the mangano-superoxide dismutase gene (SOD2) is associated with chronic pancreatitis by Pfützer, R.H, Weiss, C, Kylanpää, M.L, Diaconu, B, Bugert, P, Unterschütz, H, Jöres-Nguyen-Xuan, T.H, Lempinen, M, Kemppainen, E, Singer, M.V, Schneider, A

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699 TGF-β ENHANCES ALCOHOL DEPENDENT HEPATOCYTE DAMAGE VIA DOWNREGULATION OF ALCOHOL DEHYDROGENASE I by Ciuclan, L, Ehnert, S, Ilkavets, I, Weng, H.-L, Gaitantzi, H, Tsukamoto, H, Breitkopf, K, Dooley, S, Singer, M.V

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105 NOTCH SIGNALING PLAYS A CRITICAL ROLE IN EXPERIMENTAL AND HUMAN LIVER FIBROGENSIS by Dooley, S, Liu, Y, Ilkavets, I, Shen, H, Zimmer, V, Bohle, R.M, Zhu, C, Xu, C, Yu, C, Meyer, C, Ciuclan, L, Stump, C, Müller, A, Huang, T, Li, Y, Lammert, F, Singer, M.V, Mertens, P.R, Weng, H.-L

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1058 ANALYSIS OF CELLULAR ORIGIN AND DEGRADATION PATHWAYS OF THE ENDOCANNABINOID 2-ARACHIDONOYL GLYCEROL DURING LIVER FIBROGENESIS by Wojtalla, A, Herweck, F, Singer, M.V, Sauerbruch, T, Zimmer, A, Siegmund, S.V

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984 ELEVATED ENDOCANNABINOID LEVELS DURING LIVER FIBROGENESIS ARE DRIVEN BY DIMINISHED HEPATIC EXPRESSION AND ACTIVITY OF ENDOCANNABINOID DEGRADING ENZYMES by Siegmund, S.V, Wojtalla, A, Herweck, F, Zimmer, A, Singer, M.V

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Interfering with interferon-γ signalling in intestinal epithelial cells: selective inhibition of apoptosis-maintained secretion of anti-inflammatory interleukin-18 binding protein by Schuhmann, D, Godoy, P, Weiß, C, Gerloff, A, Singer, M.V, Dooley, S, Böcker, U

“…The intestinal epithelial barrier represents an important component in the pathogenesis of inflammatory bowel diseases. Interferon (IFN)-γ, a T helper type 1…”
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Functional P2X₇ Receptor Polymorphisms (His155Tyr, Arg307Gln, Glu496Ala) in Patients with Crohn's Disease by Haas, S.L, Ruether, A, Singer, M.V, Schreiber, S, Böcker, U

“…Genetic factors contribute to inflammatory bowel diseases. Recently, the P2X₇ receptor was found to be a key player in caspase-1-mediated processing of the…”
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Role of M1- and cholecystokinin (CCK)-a-receptors in the enteropancreatic reflexes by Niebergall-Roth, E., Teyssen, S., Singer, M.V.

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Different effects of the M1-receptor antagonist telenzepine on endogenously vs. exogenously-stimulated canine pancreatic enzyme secretion by Niebergall-Roth, E., Teyssen, S., Singer, M.V.

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Different IL-12 p40 response in patients with hepatitis c virus -induced cirrhosis and alcoholic cirrhosis by Hanck, Ch, Singer, M.V., Rossol, S.

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COMMON HFE MUTATIONS ARE NOT ASSOCIATED WITH CHRONIC PANCREATITIS by Hucl, T., Kylanpää-Bäck, M.-L., Künzli, B., Lempinen, M., Schneider, A., Friess, H., Löhr, J.M., Kemppainen, E., Singer, M.V., Pfützer, R.H.

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