Search Results - "Singer, Jeffrey R"
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1
Daughter’s Tolerance of Mom Matters in Mate Choice
Published in Cell (30-07-2015)“…Mendelian genetics presumes inheritance of fitness through DNA. Kinder et al. find that maternal microchimerism induces stable immune tolerance to…”
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Journal Article -
2
Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells
Published in Science (American Association for the Advancement of Science) (14-09-2018)“…In response to infection, naïve CD4 T cells differentiate into two subpopulations: T follicular helper (T ) cells, which support B cell antibody production,…”
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Journal Article -
3
Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis
Published in Nature medicine (01-11-2019)“…Late-onset sepsis (LOS) is thought to result from systemic spread of commensal microbes from the intestines of premature infants. Clinical use of probiotics…”
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Journal Article -
4
A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts
Published in Immunity (Cambridge, Mass.) (08-03-2022)“…Interleukin (IL)-22 is central to immune defense at barrier sites. We examined the contributions of innate lymphoid cell (ILC) and T cell-derived IL-22 during…”
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Journal Article -
5
A Non-redundant Role for T cell-derived Interleukin 22 in Antibacterial Defense of Colonic Crypts
Published in Immunity (Cambridge, Mass.) (08-03-2022)“…Interleukin (IL)-22 is central to immune defense at barrier sites. We examined the contributions of innate lymphoid cell (ILC) and T cell-derived IL-22 during…”
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Journal Article -
6
Differential IL-2 Expression Defines Developmental Fates of Follicular versus Non-follicular Helper T cells
Published in Science (American Association for the Advancement of Science) (14-09-2018)“…In response to infection, naïve CD4 + T cells differentiate into two types of helpers: T follicular helper (Tfh) cells, which support B-cell antibody…”
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Journal Article -
7
Susceptibility to Late-onset Sepsis Is Controlled by the Neonatal Microbiome and Intestinal Immune System
Published 01-01-2018“…When mammals leave the womb, they encounter a world teeming with microbial life. Their intestinal tract, which will ultimately harbor an ecosystem of trillions…”
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Dissertation