Search Results - "Singer, Jason M"

Multiple antisense oligonucleotides targeted against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1 by Lutkewitte, Andrew J., Singer, Jason M., Shew, Trevor M., Martino, Michael R., Hall, Angela M., He, Mai, Finck, Brian N.

“…Monoacylglycerol acyltransferase (MGAT) enzymes catalyze the synthesis of diacylglycerol from monoacylglycerol. Previous work has suggested the importance of…”
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Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice by Yiew, Nicole K.H., Deja, Stanislaw, Ferguson, Daniel, Cho, Kevin, Jarasvaraparn, Chaowapong, Jacome-Sosa, Miriam, Lutkewitte, Andrew J., Mukherjee, Sandip, Fu, Xiaorong, Singer, Jason M., Patti, Gary J., Burgess, Shawn C., Finck, Brian N.

“…The liver coordinates the systemic response to nutrient deprivation and availability by producing glucose from gluconeogenesis during fasting and synthesizing…”
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Mdm20 Protein Functions with Nat3 Protein to Acetylate Tpm1 Protein and Regulate Tropomyosin-Actin Interactions in Budding Yeast by Singer, Jason M., Shaw, Janet M.

“…The evolutionarily conserved Mdm20 protein (Mdm20p) plays an important role in tropomyosin-F-actin interactions that generate actin filaments and cables in…”
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1575-P: Glycerol Metabolism and Gluconeogenesis in Mice Lacking the Mitochondrial Pyruvate Carrier in Hepatocytes by YIEW, NICOLE, FERGUSON, DANIEL, CHO, KEVIN, DEJA, STANISLAW, JARASVARAPARN, CHAOWAPONG, FU, XIAORONG, LUTKEWITTE, ANDREW J., MUKHERJEE, SANDIP, SINGER, JASON M., PATTI, GARY J., BURGESS, SHAWN C., FINCK, BRIAN N.

“…Hepatic glucose production from glycogen breakdown and gluconeogenic substrates is an important physiologic adaptation, but uncontrolled glucose release by the…”
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Monoacylglycerol O‐acyltransferase 1 lowers adipocyte differentiation capacity in vitro but does not affect adiposity in mice by Singer, Jason M., Shew, Trevor M., Ferguson, Daniel, Renkemeyer, M. Katie, Pietka, Terri A., Hall, Angela M., Finck, Brian N., Lutkewitte, Andrew J.

“…Objective Monoacylglycerol O‐acyltransferase 1 (Mogat1), a lipogenic enzyme that converts monoacylglycerol to diacylglycerol, is highly expressed in adipocytes…”
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Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids by Martino, Michael R., Gutiérrez-Aguilar, Manuel, Yiew, Nicole K.H., Lutkewitte, Andrew J., Singer, Jason M., McCommis, Kyle S., Ferguson, Daniel, Liss, Kim H.H., Yoshino, Jun, Renkemeyer, M. Katie, Smith, Gordon I., Cho, Kevin, Fletcher, Justin A., Klein, Samuel, Patti, Gary J., Burgess, Shawn C., Finck, Brian N.

“…Hepatic gluconeogenesis from amino acids contributes significantly to diabetic hyperglycemia, but the molecular mechanisms involved are incompletely…”
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A Comprehensive Review of Sex Disparities in Symptoms, Pathophysiology, and Epidemiology of Dry Eye Syndrome by Rapoport, Yuna, Singer, Jason M., Ling, Jeanie D., Gregory, Anthony, Kohanim, Sahar

“…Introduction: The etiology, frequency, manifestation, and treatment of dry eye syndrome are commonly influenced by sex and gender. Materials and Methods: This…”
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Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids by Martino, Michael R., Gutiérrez-Aguilar, Manuel, Yiew, Nicole K.H., Lutkewitte, Andrew J., Singer, Jason M., McCommis, Kyle S., Ferguson, Daniel, Liss, Kim H.H., Yoshino, Jun, Renkemeyer, M. Katie, Smith, Gordon I., Cho, Kevin, Fletcher, Justin A., Klein, Samuel, Patti, Gary J., Burgess, Shawn C., Finck, Brian N.

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Adipocyte lipin 1 expression associates with human metabolic health and regulates systemic metabolism in mice by LaPoint, Andrew, Singer, Jason M, Ferguson, Daniel, Shew, Trevor M, Renkemeyer, M Katie, Palacios, Hector H, Field, Rachael L, Yerrathota, Sireeesha, Kumari, Roshan, Shankaran, Mahalakshmi, Smith, Gordon I, Yoshino, Jun, He, Mai, Patti, Gary J, Hellerstein, Marc K, Klein, Samuel, Morris, E Matthew, Brestoff, Jonathan R, Finck, Brian N, Lutkewitte, Andrew

“…Dysfunctional adipose tissue is believed to promote the development of hepatic steatosis and systemic insulin resistance, but many of the mechanisms involved…”
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Bioactive nanoparticles improve calcium handling in failing cardiac myocytes by Maxwell, Joshua T, Somasuntharam, Inthirai, Gray, Warren D, Shen, Ming, Singer, Jason M, Wang, Bo, Saafir, Talib, Crawford, Brian H, Jiang, Rong, Murthy, Niren, Davis, Michael E, Wagner, Mary B

“…To evaluate the ability of -acetylglucosamine (GlcNAc) decorated nanoparticles and their cargo to modulate calcium handling in failing cardiac myocytes (CMs)…”
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Suppressors of mdm20 in yeast identify new alleles of ACT1 and TPM1 predicted to enhance actin-tropomyosin interactions by Singer, J M, Hermann, G J, Shaw, J M

“…The actin cytoskeleton is required for many aspects of cell division in yeast, including mitochondrial partitioning into growing buds (mitochondrial…”
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Monoacylglycerol O-acyltransferase 1 Lowers Adipocyte Differentiation Capacity in Vitro but Does Not Affect Adiposity in Mice by Singer, Jason M, Shew, Trevor M, Ferguson, Daniel, Renkemeyer, M Katie, Pietka, Terri A, Hall, Angela M, Finck, Brian N, Lutkewitte, Andrew J

“…Objective: Monoacylglycerol O-acyltransferase 1 (Mogatl), a lipogenic enzyme that converts monoacylglycerol to diacylglycerol, is highly expressed in…”
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The function of Mdm20p in yeast mitochondrial inheritance: Regulation of tropomyosin-actin interactions by Singer, Jason M

“…The compartmentalization of organelles in eukaryotic cells has necessitated their development of the means to transport organelles where and when they are…”
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The function of Mdm20p in yeast mitochondrial inheritance: Regulation of tropomyosin-actin interactions by Singer, Jason M

“…The compartmentalization of organelles in eukaryotic cells has necessitated their development of the means to transport organelles where and when they are…”
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