Search Results - "Singer, Heiko"
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Effective Elimination of Acute Myeloid Leukemic Cells by Recombinant Bispecific Antibody Derivatives Directed Against CD33 and CD16
Published in Journal of immunotherapy (1997) (01-07-2010)“…Single-chain Fv triplebodies (sctb), consisting of a single polypeptide chain with 3 single-chain antibody variable fragments connected in tandem, were…”
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2
A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting
Published in mAbs (01-01-2011)“…A single-chain triplebody (sctb) 33-ds16-ds19 comprising two distal single-chain Fv fragments (scFvs) specific for the lymphoid antigen CD19 and the myeloid…”
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Journal Article -
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A recombinant trispecific single‐chain Fv derivative directed against CD123 and CD33 mediates effective elimination of acute myeloid leukaemia cells by dual targeting
Published in British journal of haematology (01-09-2010)“…Summary Two trivalent constructs consisting of single‐chain Fv antibody fragments (scFvs) specific for the interleukin‐3 receptor α chain (CD123), CD33 and the…”
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4
A novel CD19-directed recombinant bispecific antibody derivative with enhanced immune effector functions for human leukemic cells
Published in Journal of immunotherapy (1997) (01-11-2008)“…A novel bispecific antibody-derived recombinant protein targeting leukemias and lymphomas was designed, a single-chain Fv triple body (sctb) consisting of 1…”
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Journal Article