Search Results - "Singaraju, Aditya B"
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Combining Crystal Structure and Interaction Topology for Interpreting Functional Molecular Solids: A Study of Theophylline Cocrystals
Published in Crystal growth & design (06-12-2017)“…The acoustic frequency distributions, mechanical moduli, and crystal structures for theophylline (THY) and three cocrystals are combined to illustrate how…”
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2
Current State of Minitablet Product Design: A Review
Published in Journal of pharmaceutical sciences (01-05-2024)“…Interest in minitablets (MTs) has grown exponentially over the last 20 years and especially the last decade, as evidenced by the number of publications cited…”
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Molecular Interpretation of the Compaction Performance and Mechanical Properties of Caffeine Cocrystals: A Polymorphic Study
Published in Molecular pharmaceutics (06-01-2020)“…The 1:1 caffeine (CAF) and 3-nitrobenzoic acid (NBA) cocrystal (CAF:NBA) displays polymorphism. Each polymorph shares the same docking synthon that connects…”
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Brillouin Light Scattering: Development of a Near Century-Old Technique for Characterizing the Mechanical Properties of Materials
Published in AAPS PharmSciTech (01-04-2019)“…Brillouin light scattering (BLS), a technique theoretically described nearly a century back by the French physicist Léon Brillouin in 1922, is a…”
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Structure–Mechanics and Compressibility Profile Study of Flufenamic Acid:Nicotinamide Cocrystal
Published in Crystal growth & design (03-10-2018)“…A contribution of crystal structure, mechanical moduli, and macroscopic compression properties of flufenamic acid (FFA) and its cocrystal with nicotinamide…”
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Aggregate Elasticity and Tabletability of Molecular Solids: a Validation and Application of Powder Brillouin Light Scattering
Published in AAPS PharmSciTech (01-11-2018)“…Describing the elastic deformation of single-crystal molecular solids under stress requires a comprehensive determination of the fourth-rank stiffness tensor…”
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Caffeine Co-Crystal Mechanics Evaluated with a Combined Structural and Spectroscopic Approach
Published in Crystal growth & design (03-08-2016)“…In this report caffeine (CAF) co-crystallization with a fluoro-nitrobenzoic acid (F-NBA) yields a new solid form with superior tableting performance. A primary…”
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Dipalmitoylphosphatidylcholine (DPPC): Annealing Strategy to Mitigate Variability in Thermotropic and Moisture Sorption Behavior
Published in Journal of pharmaceutical sciences (01-10-2018)“…Dipalmitoylphosphatidylcholine (DPPC) demonstrated complex differential scanning calorimetry (DSC) thermal behavior. Transitions below 100°C showed variability…”
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Aggregate Elasticity, Crystal Structure, and Tableting Performance for p‑Aminobenzoic Acid and a Series of Its Benzoate Esters
Published in Molecular pharmaceutics (07-11-2016)“…The tableting performance for p-aminobenzoic acid (PABA) and a series of its benzoate esters with increasing alkyl chain length (methyl-, ethyl-, and n-butyl)…”
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