The relationship between retrobulbar and choroidal hemodynamics in non-neovascular age-related macular degeneration

To evaluate the relationship between retrobulbar and choroidal hemodynamics in non-neovascular age-related macular degeneration. Thirteen patients with age-related macular degeneration were assessed by both color Doppler imaging and scanning laser ophthalmoscope indocyanine green (ICG) angiography....

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Bibliographic Details
Published in:	Ophthalmic surgery, lasers & imaging Vol. 38; no. 3; p. 219
Main Authors:	Rechtman, Ehud, Harris, Alon, Siesky, Brent, Kagemann, Larry, Danis, Ronald P, Sines, Dan, Ciulla, Thomas A
Format:	Journal Article
Language:	English
Published:	United States 01-05-2007
Subjects:	Aged Blood Flow Velocity Choroid - blood supply Ciliary Arteries - diagnostic imaging Ciliary Arteries - physiology Coloring Agents Female Fluorescein Angiography Humans Indocyanine Green Macular Degeneration - diagnostic imaging Macular Degeneration - physiopathology Male Ophthalmic Artery - diagnostic imaging Ophthalmic Artery - physiology Ophthalmoscopy Orbit - blood supply Regional Blood Flow Retinal Artery - diagnostic imaging Retinal Artery - physiology Ultrasonography, Doppler, Color
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Summary:	To evaluate the relationship between retrobulbar and choroidal hemodynamics in non-neovascular age-related macular degeneration. Thirteen patients with age-related macular degeneration were assessed by both color Doppler imaging and scanning laser ophthalmoscope indocyanine green (ICG) angiography. Color Doppler imaging was used to measure peak systolic and end diastolic velocity (from which the resistance index, a measure of the resistance to flow downstream, was calculated) in the retrobulbar vessels. Scanning laser ophthalmoscope ICG angiograms were analyzed by area dilution analysis for quantitative choroidal fluorescence intensity assessment. Color Doppler imaging parameters were correlated with scanning laser ophthalmoscope ICG area dilution analysis parameters. A good correlation was found between the posterior ciliary arteries resistance index and scanning laser ophthalmoscope ICG area dilution analysis fluorescence duration. Scanning laser ophthalmoscope ICG area dilution analysis "duration" may serve as an alternative to color Doppler imaging in assessing the resistance to blood flow in the posterior ciliary arteries.
ISSN:	1542-8877
DOI:	10.3928/15428877-20070501-06