Search Results - "Sinenko, A A"
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Interaction between Differentiating Cell- and Niche-Derived Signals in Hematopoietic Progenitor Maintenance
Published in Cell (23-12-2011)“…Maintenance of a hematopoietic progenitor population requires extensive interaction with cells within a microenvironment or niche. In the Drosophila…”
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2
Physiological Signaling Functions of Reactive Oxygen Species in Stem Cells: From Flies to Man
Published in Frontiers in cell and developmental biology (06-08-2021)“…Reactive oxygen species (ROS), superoxide anion and hydrogen peroxide, are generated as byproducts of oxidative phosphorylation in the mitochondria or via cell…”
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3
Pluripotent stem cell-based gene therapy approach: human de novo synthesized chromosomes
Published in Cellular and molecular life sciences : CMLS (01-02-2021)“…A novel approach in gene therapy was introduced 20 years ago since artificial non-integrative chromosome-based vectors containing gene loci size inserts were…”
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4
Oxidative stress in the haematopoietic niche regulates the cellular immune response in Drosophila
Published in EMBO reports (01-01-2012)“…Oxidative stress induced by high levels of reactive oxygen species (ROS) is associated with the development of different pathological conditions, including…”
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5
Dual Mode of Mitochondrial ROS Action during Reprogramming to Pluripotency
Published in International journal of molecular sciences (18-09-2022)“…Essential changes in cell metabolism and redox signaling occur during the reprogramming of somatic cells into induced pluripotent stem cells (iPSCs). In this…”
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6
Human artificial chromosomes for pluripotent stem cell-based tissue replacement therapy
Published in Experimental cell research (01-04-2020)“…The gene therapy approach aiming at curing various human diseases began to develop as a technology from early eighties of the last century. To date the…”
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7
Metabolic control of induced pluripotency
Published in Frontiers in cell and developmental biology (11-01-2024)“…Pluripotent stem cells of the mammalian epiblast and their cultured counterparts-embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs)-have the capacity…”
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8
Tryptophan Hydroxylase-2-Mediated Serotonin Biosynthesis Suppresses Cell Reprogramming into Pluripotent State
Published in International journal of molecular sciences (01-03-2023)“…The monoamine neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has important functions both in the neural system and during embryonic development in…”
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9
Dual Role of Wingless Signaling in Stem-like Hematopoietic Precursor Maintenance in Drosophila
Published in Developmental cell (01-05-2009)“…In Drosophila, blood development occurs in a specialized larval hematopoietic organ, the lymph gland (LG), within which stem-like hemocyte precursors or…”
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10
The Composition and Kinetics of the Hemocyte Population in the Mussel Crenomytilus grayanus (Dunker, 1853)
Published in Russian journal of marine biology (01-08-2022)“…Based on light microscopy data, hemocytes of Crenomytilus grayanus were classified into five morphological types common for Bivalvia. In the stage of sexual…”
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11
Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila
Published in Blood (08-01-2015)“…Gain-of-function mutations in nicotinamide adenine dinucleotide phosphate–dependent isocitrate dehydrogenase (IDH)1 and IDH2 frequently arise in human…”
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12
Age-Related and Seasonal Dynamics of the Hemocyte Population in the Mussel Crenomytilus grayanus (Dunker, 1853)
Published in Russian journal of marine biology (01-04-2023)“…The cellular composition of the hemolymph of the mussel Crenomytilus grayanus is represented by hemoblasts, hyalinocytes, basophilic, neutrophilic and…”
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13
Increased expression of Drosophila tetraspanin, Tsp68C, suppresses the abnormal proliferation of ytr-deficient and Ras/Raf-activated hemocytes
Published in Oncogene (02-12-2004)“…Tetraspanins are evolutionary conserved transmembrane proteins thought to facilitate cell proliferation, movement or fusion by acting as organizers of…”
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14
Human Artificial Chromosomes and Their Transfer to Target Cells
Published in Actanaturae (01-07-2022)“…Human artificial chromosomes (HACs) have been developed as genetic vectors with the capacity to carry large transgenic constructs or entire gene loci. HACs…”
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15
Genetic tool for fate mapping of Oct4 (Pou5f1)-expressing cells and their progeny past the pluripotency stage
Published in Stem cell research & therapy (16-12-2019)“…Methods based on site-specific recombinases are widely used in studying gene activities in vivo and in vitro. In these studies, constitutively active or…”
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16
Genetic manipulation of AML1-ETO–induced expansion of hematopoietic precursors in a Drosophila model
Published in Blood (25-11-2010)“…Among mutations in human Runx1/AML1 transcription factors, the t(8;21)(q22;q22) genomic translocation that creates an AML1-ETO fusion protein is implicated in…”
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17
Prospects for the use of solar energy to accelerate the hardening of concrete in the construction of monolithic structures in Russia
Published in E3S Web of Conferences (01-01-2021)“…This article addresses the issue of solving the problem of using the solar energy, that allows decreasing of the unit costs, or even avoiding using of the…”
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18
Transfer of Synthetic Human Chromosome into Human Induced Pluripotent Stem Cells for Biomedical Applications
Published in Cells (Basel, Switzerland) (08-12-2018)“…Alphoid -type human artificial chromosome (HAC) has been recently synthetized as a novel class of gene delivery vectors for induced pluripotent stem cell…”
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19
Property Taxation of Companies in Territories With a Special Economic Status
Published in Finansovyj žurnal (Online) (01-06-2022)“…The article is devoted to the study of fiscal mechanisms of regulation of property taxation in the territories with a special economic status. The purpose of…”
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20
Molecular Mechanisms of Drosophila Hematopoiesis
Published in Actanaturae (01-04-2024)“…As a model organism, the fruit fly ( ) has assumed a leading position in modern biological research. The genetic system has a number of advantages making it a…”
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