Search Results - "Sinclair, N. C."

Limitations in the Rapid Extraction of Evoked Potentials Using Parametric Modeling by De Silva, A. C., Sinclair, N. C., Liley, D. T. J.

“…The rapid extraction of variations in evoked potentials (EPs) is of great clinical importance. Parametric modeling using autoregression with an exogenous input…”
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Propofol and Remifentanil Differentially Modulate Frontal Electroencephalographic Activity by LILEY, David T. J, SINCLAIR, Nicholas C, LIPPING, Tarmo, HEYSE, Bjorn, VEREECKE, Hugo E. M, STRUYS, Michel M. R. F

“…The purpose of this study was to evaluate a new, physiologically inspired method for the analysis of the electroencephalogram during propofol-remifentanil…”
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neuroBi: A Highly Configurable Neurostimulator for a Retinal Prosthesis and Other Applications by Slater, K. D., Sinclair, N. C., Nelson, T. S., Blamey, P. J., Mcdermott, H. J.

“…To evaluate the efficacy of a suprachoroidal retinal prosthesis, a highly configurable external neurostimulator is required. In order to meet functional and…”
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Dissociating the effects of nitrous oxide on brain electrical activity using fixed order time series modeling by Liley, David T.J, Leslie, Kate, Sinclair, Nicholas C, Feckie, Martin

“…Abstract A number of commonly used anesthetics, including nitrous oxide (N2 O), are poorly detected by current electroencephalography (EEG)-based measures of…”
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Immunosuppressive activity of an extract of Listeria monocytogenes by Kim, J J, St C Sinclair, N R, Singhal, S K, Carroll, K K

“…The effects of treatment of mice with an aqueous extract of Listeria monocytogenes on lymphoid populations and on immune responsiveness were studied. Thymus…”
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Fc‐Signalling in the Modulation of Immune Responses by Passive Antibody by Sinclair, N. R. StC

“…Passive antibody can both suppress and augment immune responses. Until recently, there was virtual unanimity on the importance of the interaction of the Fc…”
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Why So Many Coinhibitory Receptors? by Sinclair, N R

“…Receptors that display negative signalling functions on lymphocytes and other cells of the reticuloendothelial system now number about 30. These negative…”
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Reply: Some Afterthoughts – Pragmatic and Philosophical by Sinclair, N. R. StC

“…Conditions under which one searches for Fc‐signalling determine the success in finding it. A major condition is that one must have enough T cells to drive a…”
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Co-stimulation and co-inhibition: equal partners in regulation by Sinclair, N R, Anderson, C C

“…Specific immune responses are controlled by two counterbalancing mechanisms-co-stimulation and co-inhibition. Antigen receptors determine specificity, activate…”
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Effect of major histocompatibility complex expression on murine intestinal graft survival by CAGIANNOS, C, ZHONG, R, ZANG, Z, JIANG, J, GARCIA, B. M, CHAKRABARTI, S, JEVNIKAR, A. M, SINCLAIR, N. R. C, GRANT, D. R

“…Clinical intestinal transplantation has been plagued by frequent and severe graft rejection. It has been proposed that the major histocompatibility complex…”
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Hypogammaglobulinaemia occurs in Fas‐deficient MRL‐lpr mice following deletion of MHC class II molecules by ANDERSON, C. C., MUKHERJEE, R., SINCLAIR, N. R. StC, JEVNIKAR, A. M.

“…Fas (CD95)‐mediated apoptosis in B and T cells is deficient in both human autoimmune lymphoproliferative syndrome and in MRL‐lpr mice, a model for systemic…”
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Effects of a gold salt on lymphocyte responses by Harth, M, Stiller, C R, St C Sinclair, N R, Evans, J, McGirr, D, Zuberi, R

“…The effects of sodium aurothiomalate (SATM) on certain lymphocyte functions in vitro were tested. Lymphocytes were obtained from both healthy donors and…”
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Can B-cell signalling be understood? by Sinclair, N R

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Antibody response and its regulation by Sinclair, N R, Panoskaltsis, A

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Cell-mediated cytotoxicity against syngeneic tumors by Sinclair, N R, McFarlane, D L, Low, J M

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Rheumatoid factor and Fc signaling: a tale of two Cinderellas by Sinclair, N R, Panoskaltsis, A

“…Signaling to lymphocytes depends not only upon the interaction of receptors with specific antigen, but also upon antigen nonspecific receptors which receive…”
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Regulation of the immune response. VIII. Characteristics of antibody-mediated suppression of an in vitro cell-mediated immune response by Sinclair, N R, Lees, R K, Fagan, G, Birnbaum, A

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Mutual antagonism between antigen- and lipopolysaccharide-induced antibody production by Anderson, C C, Rahimpour, R, Sinclair, N R

“…B cells are induced to antibody production by antigens or by mitogens, such as lipopolysaccharide (LPS). We observed a mutually antagonistic relationship…”
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Role of the Fc Fragment in the Regulation of the Primary Immune Response by SINCLAIR, N. R. STC, LEES, ROSEMARY K, ELLIOTT, E. V

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Effects of neonatal thymectomy on the haemolysin response to sheep erythrocytes in Swiss albino mice. A time-course study of total, 19S and 7S antibody by Sinclair, N R

“…Mice thymectomized within 24 hours of birth were immunized by intraperitoneal injection of sheep erythrocytes at 6 weeks of age and again 60 days later. Serum…”
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