Search Results - "Sinay, Pierre"

Study on Metal-Induced Reactions of α‑Diazocarbonyl Glucosides by Guan, Zhu, Zhang, Li-He, Sinaÿ, Pierre, Zhang, Yongmin

“…Conversions of diazocarbonyl carbohydrate compounds catalyzed by a series of rhodium and copper catalysts in conventional heating or microwave conditions were…”
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Conjugation of cyclodextrin with fullerene as a new class of HCV entry inhibitors by Xiao, Su-long, Wang, Qi, Yu, Fei, Peng, Yi-yun, Yang, Ming, Sollogoub, Matthieu, Sinaÿ, Pierre, Zhang, Yong-min, Zhang, Li-he, Zhou, De-min

“…An α-cyclodextrin–[60]fullerene conjugate with a flexible linker at the secondary face of α-cyclodextrin has been prepared, which displays significant water…”
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A New Methodology for the Synthesis of Fluorinated exo-Glycals and Their Time-Dependent Inhibition of UDP-Galactopyranose Mutase by Caravano, Audrey, Dohi, Hirofumi, Sinaÿ, Pierre, Vincent, Stéphane P.

“…Fluorinated carbohydrates constitute a very important class of mechanistic probes for glycosyl‐processing enzymes. In this study, we describe the first…”
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Synthesis and Inhibition Properties of Conformational Probes for the Mutase-Catalyzed UDP-Galactopyranose/Furanose Interconversion by Caravano, Audrey, Mengin-Lecreulx, Dominique, Brondello, Jean-Marc, Vincent, Stéphane P., Sinaÿ, Pierre

“…UDP‐galactose mutase is a flavoenzyme that catalyzes the isomerization of UDP‐galactopyranose into UDP‐galactofuranose, a key step in the biosynthesis of…”
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Stereochemical Assignment and First Synthesis of the Core of Miharamycin Antibiotics by Marcelo, Filipa, Jiménez-Barbero, Jesús, Marrot, Jérôme, Rauter, Amélia P., Sinaÿ, Pierre, Blériot, Yves

“…The relative configuration at C‐6′ of nucleoside antibiotic miharamycin A has been elucidated by NMR spectroscopy and proved to be S. The total synthesis of…”
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Synthesis of novel purine nucleosides towards a selective inhibition of human butyrylcholinesterase by Marcelo, Filipa, Silva, Filipa V.M., Goulart, Margarida, Justino, Jorge, Sinaÿ, Pierre, Blériot, Yves, Rauter, Amélia P.

“…Novel N 7 2-aminopurine nucleosides were synthesized and demonstrated a high potential for the selective inhibition of butyrylcholinesterase, as well as some…”
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Expression of Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase Isoforms Reveals Novel Substrate Specificities by Liu, J, Shworak, N W, Sinaÿ, P, Schwartz, J J, Zhang, L, Fritze, L M, Rosenberg, R D

“…The 3- O -sulfation of glucosamine residues is an important modification during the biosynthesis of heparan sulfate (HS). Our previous studies have led us to…”
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gem-Difluoro-carbasugars, the cases of mannopyranose and galactopyranose by Sardinha, João, Guieu, Samuel, Deleuze, Aurélie, Fernández-Alonso, M. Carmen, Rauter, Amelia Pilar, Sinaÿ, Pierre, Marrot, Jérôme, Jiménez-Barbero, Jesús, Sollogoub, Matthieu

“…5a-Difluoro-5a-carbamannopyranose (gem-difluoro-carbamannopyranose) and 5a-difluoro-5a-carbagalactopyranose (gem-difluoro-carbagalactopyranose), close…”
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Synthesis of two mono-deoxy β-cyclodextrin derivatives as useful tools for confirming DIBAL-H promoted bis-de-O-methylation mechanism by Xiao, Su Long, Zhou, De Min, Yang, Ming, Yu, Fei, Zhang, Li He, Sinaÿ, Pierre, Zhang, Yong Min

“…Diisobutylaluminium hydride （DIBAL-H） promotes secondary rim regioselective bis-de-O-methylation of permethylated β- cyclodextrin （β-CD） to give diol 2. To…”
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Preparation of unsymmetrically 2A,3B,6C(F)-trihydroxy-per-O-methylated α-cyclodextrin and NMR analysis by Xiao, Sulong, Zhou, Demin, Zhang, Lihe, Sinaÿ, Pierre, Zhang, Yongmin

“…Asterisk indicated that the position of hydroxyl locate at C or F glucose residue. [Display omitted] •DIBAL-H promoted simultaneous de-O-methylation on both…”
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Complex Biohopanoids Synthesis: Efficient Anchoring of Ribosyl Subunits onto a C 30  Hopane by Pan, Weidong, Sun, Chao, Zhang, Yongmin, Liang, Guangyi, Sinaÿ, Pierre, Vincent, Stéphane P.

“…Abstract Bacteriohopanoids represent a particularly important series of triterpenoids, widely distributed in bacteria. One of the common features of these…”
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Hemicarbasucrose: Turning off the Exoanomeric Effect Induces Less Flexibility by López-Méndez, Blanca, Jia , Cai, Zhang, Yongmin, Zhang, Li-He, Sinaÿ, Pierre, Jiménez-Barbero, Jesús, Sollogoub, Matthieu

“…Hemicarbasucrose, a close congener of sucrose in which the endocyclic oxygen atom of the glucose moiety is replaced by a methylene group was synthesized for…”
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Composite hopanoid biosynthesis in Zymomonas mobilis: N-acetyl-D-glucosamine as precursor for the cyclopentane ring linked to bacteriohopanetetrol by Vincent, Stéphane P, Sinaÿ, Pierre, Rohmer, Michel

“…A selective labelling of the two major composite hopanoids of Z. mobilis with deuterated N-acetyl-D-glucosamine showed that this carbohydrate is a common…”
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Complexation between a Hydrophobically Modified Chitosan and Cyclodextrin Homodimers Singly or Doubly Connected through Their Primary Sides: Effects of Their Molecular Architecture on the Polymer Properties in Solution by Lecourt, Thomas, Sinaÿ, Pierre, Chassenieux, Christophe, Rinaudo, Marguerite, Auzély-Velty, Rachel

“…The complexation properties toward adamantane-grafted chitosan of two β-cyclodextrin (CD) homodimers, containing two CD moieties that are linked through their…”
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Photophysical studies of six amphiphilic 2:1 cyclodextrin:[60]fullerene derivatives by Quaranta, Annamaria, Zhang, Yongmin, Filippone, Salvatore, Yang, Juan, Sinaÿ, Pierre, Rassat, André, Edge, Ruth, Navaratnam, Suppiah, McGarvey, David J., Land, Edward J., Brettreich, Michael, Hirsch, Andreas, Bensasson, René V.

“…In search of a simple internal complexation of C 60 in cyclodextrins, six 2:1 cyclodextrin:[60]fullerene conjugates involving different types of linkers have…”
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Synthesis of four mono-functionalized α-cyclodextrin derivatives for further confirming DIBAL-H-promoted bis-de-O-methylation mechanism by Xiao, Sulong, Yang, Ming, Yu, Fei, Zhang, Lihe, Zhou, Demin, Sinaÿ, Pierre, Zhang, Yongmin

“…In our previous studies, a mechanism for DIBAL-H promoted regioselective bis-de-O-methylation of per-O-methylated cyclodextrin (CD) was proposed based on…”
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Sugars slide into heparin activity by Sinay, Pierre

“…Researchers have designed and chemically synthesized a complex oligosaccharide that is ten times more potent in vivo than standard heparin and…”
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The First Chemical Synthesis of a Cyclodextrin Heteroduplex by Bistri, Olivia, Lecourt, Thomas, Mallet, Jean-Maurice, Sollogoub, Matthieu, Sinaÿ, Pierre

“…The synthesis of the first heteroduplex of cyclodextrin (CD) 11, i.e., a compound in which the two primary rims of α‐ and β‐CDs are doubly connected, was…”
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Triisobutylaluminium and Diisobutylaluminium Hydride as Molecular Scalpels: The Regioselective Stripping of Perbenzylated Sugars and Cyclodextrins by Lecourt, Thomas, Herault, Alexandre, Pearce, Alan J., Sollogoub, Matthieu, Sinaÿ, Pierre

“…To explain the remarkable regioselective de‐O‐benzylating properties of diisobutylaluminium hydride (DIBAL‐H) and triisobutylaluminium (TIBAL) towards…”
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Tandem Staudinger-azaWittig mediated ring expansion: rapid access to new isofagomine-tetrahydroxyazepane hybrids by Li, Hongqing, Zhang, Yongmin, Vogel, Pierre, Sinaÿ, Pierre, Blériot, Yves

“…New seven-membered iminosugars with potent and selective inhibition towards glycosidases have been prepared as 1-N-iminosugar homologues via a tandem…”
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