Search Results - "Sinaÿ, P"
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Catching elusive glycosyl cations in a condensed phase with HF/SbF5 superacid
Published in Nature chemistry (01-02-2016)“…Glycosyl cations are universally accepted key ionic intermediates in the mechanism of glycosylation, the reaction that covalently links carbohydrates to other…”
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Synthesis of oligosaccharide mimetics
Published in Pure and applied chemistry (01-01-1997)“…Abstract…”
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Expression of Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase Isoforms Reveals Novel Substrate Specificities
Published in The Journal of biological chemistry (19-02-1999)“…The 3- O -sulfation of glucosamine residues is an important modification during the biosynthesis of heparan sulfate (HS). Our previous studies have led us to…”
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Ultraweak Sugar-Sugar Interactions for Transient Cell Adhesion
Published in Biophysical journal (01-03-2001)“…Carbohydrate-carbohydrate interactions are rarely considered in biologically relevant situations such as cell recognition and adhesion. One Ca 2+-mediated…”
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Carbocyclic Ring Closure of Unsaturated S-, Se-, and C-Aryl Glycosides
Published in Angewandte Chemie International Edition (17-01-2000)“…Triisobutylaluminum‐promoted rearrangement of unsaturated glycosides containing electron‐donating aglycons—such as C‐aryl glycoside 1, or O‐, S‐, and…”
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Reconstitution of Membranes Simulating “Glycosignaling Domain” and Their Susceptibility to Lyso-GM3
Published in The Journal of biological chemistry (19-05-2000)“…GM3 ganglioside at the surface of mouse melanoma B16 cells is clustered and organized with signal transducer molecules c-Src, Rho A, and focal adhesion kinase…”
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From Glucose to Cyclooctanic Carbaglucose: A New Class of Carbohydrate Mimetics
Published in Angewandte Chemie International Edition (17-07-2000)“…The sigmatropic rearrangement of the C‐vinyl glycoside 2, prepared from methyl α‐D‐glucoside (1), gives a cyclooctane derivative. Subsequent treatment of the…”
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Chemical synthesis of oligosaccharide mimetics
Published in Pure and applied chemistry (28-02-1998)“…Abstract…”
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Recent advances in the synthesis of carbohydrate mimics
Published in Pure and applied chemistry (30-08-1998)“…Abstract…”
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Beta-1,2-linked oligomannosides inhibit Candida albicans binding to murine macrophage
Published in Journal of leukocyte biology (01-07-1996)“…Interaction of Candida albicans with cells of the macrophage lineage was examined by using heat‐killed (HK) and live yeast cells. Laminarin, an analogue of the…”
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Oligosaccharides corresponding to the regular sequence of heparin : Chemical synthesis and interaction with FGF-2
Published in Bioorganic & medicinal chemistry (01-09-1999)“…It has been proposed that oligosaccharides corresponding to the so-called regular region of heparin/heparan sulfate (HS) bind to fibroblast growth factor-2…”
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A synthetic heparan sulfate pentasaccharide, exclusively containing L-iduronic acid, displays higher affinity for FGF-2 than its D-glucuronic acid-containing isomers
Published in Bioorganic & medicinal chemistry (01-08-1999)“…It has been suggested that the FGF-2 binding site on heparan sulfate chains is a trisulfated pentasaccharide containing three hexuronic acid units. The…”
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Synthetic C-oligosaccharides mimic their natural, analogous immunodeterminants in binding to three monoclonal immunoglobulins
Published in Carbohydrate research (01-03-1998)“…The binding of three monoclonal antigalactan immunoglobulins, IgAs X24, J539 and X44 to their natural haptens methyl β- d-galactopyranosyl-(1→6)- β-…”
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NMR study of a Lewis(X) pentasaccharide derivative: solution structure and interaction with cations
Published in Carbohydrate research (31-01-1999)“…The structure and conformation of the synthetic pentasaccharide Gal(beta 1-4){Fuc(alpha 1-3)}GlcNAc(beta 1-3)Gal(beta 1-4)Glc-beta OMe of the Lewis(X) family…”
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l-Iduronic acid derivatives as glycosyl donors
Published in Carbohydrate research (23-02-1996)“…O-[Methyl (2- O-acetyl-3- O-benzyl-4- O-levulinyl- α, and β l-idopyranosid)uronate] trichloroacetimidate and the corresponding n-pentenyl glycosides are…”
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Structure-activity relationship in heparin: a synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity
Published in Biochemical and biophysical research communications (31-10-1983)“…The structures of the tetrasaccharide (beta-D-glucuronic acid)1 leads to 4 (N-sulfate-3,6-di-0-sulfate-alpha-D-glucosamine)1 leads to…”
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Further studies of the ability of xyloglucan oligosaccharides to inhibit auxin-stimulated growth
Published in Plant physiology (Bethesda) (01-05-1992)“…The structural features required for xyloglucan oligosaccharides to inhibit 2,4-dichlorophenoxyacetic acid-stimulated elongation of pea stem segments have been…”
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Synthesis of a highly hydrophobic dimeric Lewis X containing glycolipid: a model for the study of homotypic carbohydrate--carbohydrate interaction
Published in Glycoconjugate journal (01-12-1999)“…This paper describes the synthesis of an octasaccharidic glycolipid 1 based on a stereo- and regioselective glycosylation between a Lewis X trisaccharidic…”
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Transfer reactions catalyzed by cyclodextrin glucosyltransferase using 4-thiomaltosyl and C-maltosyl fluorides as artificial donors
Published in Carbohydrate research (01-12-1997)“…Cyclodextrin glycosyltransferase enzyme from Bacillus circulans catalyzed the effective conversion of 4-thio-α-maltosyl fluoride into cyclo-α-(1 → 4 2…”
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