Search Results - "Sina, F."

COVID-19 Outbreak Prediction with Machine Learning by Ardabili, Sina, Mosavi, Amir, Ghamisi, Pedram, Ferdinand, Filip, Varkonyi-Koczy, Annamaria, Reuter, Uwe, Rabczuk, Timon, Atkinson, Peter

“…Several outbreak prediction models for COVID-19 are being used by officials around the world to make informed decisions and enforce relevant control measures…”
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Plasma MicroRNAs as Sensitive and Specific Biomarkers of Tissue Injury by Laterza, Omar F, Lim, Lee, Garrett-Engele, Philip W, Vlasakova, Katerina, Muniappa, Nagaraja, Tanaka, Wesley K, Johnson, Jason M, Sina, Joseph F, Fare, Thomas L, Sistare, Frank D, Glaab, Warren E

“…MicroRNAs (miRNAs) are endogenous, small noncoding RNAs. Because of their size, abundance, tissue specificity, and relative stability in plasma, miRNAs hold…”
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Profiling cancer gene mutations in longitudinal epithelial ovarian cancer biopsies by targeted next-generation sequencing: a retrospective study by Beltrame, L., Di Marino, M., Fruscio, R., Calura, E., Chapman, B., Clivio, L., Sina, F., Mele, C., Iatropoulos, P., Grassi, T., Fotia, V., Romualdi, C., Martini, P., Noris, M., Paracchini, L., Craparotta, I., Petrillo, M., Milani, R., Perego, P., Ravaggi, A., Zambelli, A., Ronchetti, E., D'Incalci, M., Marchini, S.

“…The majority of patients with stage III–IV epithelial ovarian cancer (EOC) relapse after initially responding to platinum-based chemotherapy, and develop…”
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R632W mutation in PLA2G6 segregates with dystonia-parkinsonism in a consanguineous Iranian family by Sina, F., Shojaee, S., Elahi, E., Paisán-Ruiz, C.

“…Background:  PLA2G6 mutations are known to be responsible for infantile neuroaxonal dystrophy (INAD) and neurodegeneration with brain iron accumulation (NBIA)…”
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Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: A resource for investigations into drug disposition by Bleasby, K., Castle, J. C., Roberts, C. J., Cheng, C., Bailey, W. J., Sina, J. F., Kulkarni, A. V., Hafey, M. J., Evers, R., Johnson, J. M., Ulrich, R. G., Slatter, J. G.

“…Carrier-mediated transporters play a critical role in xenobiotic disposition and transporter research is complicated by species differences and their selective…”
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Interlaboratory Evaluation of Genomic Signatures for Predicting Carcinogenicity in the Rat by Fielden, Mark R., Nie, Alex, McMillian, Michael, Elangbam, Chandi S., Trela, Bruce A., Yang, Yi, Dunn, Robert T., Dragan, Yvonne, Fransson-Stehen, Ronny, Bogdanffy, Matthew, Adams, Stephen P., Foster, William R., Chen, Shen-Jue, Rossi, Phil, Kasper, Peter, Jacobson-Kram, David, Tatsuoka, Kay S., Wier, Patrick J., Gollub, Jeremy, Halbert, Donald N., Roter, Alan, Young, Jamie K., Sina, Joseph F., Marlowe, Jennifer, Martus, Hans-Joerg, Aubrecht, Jiri, Olaharski, Andrew J., Roome, Nigel, Nioi, Paul, Pardo, Ingrid, Snyder, Ron, Perry, Richard, Lord, Peter, Mattes, William, Car, Bruce D.

“…The Critical Path Institute recently established the Predictive Safety Testing Consortium, a collaboration between several companies and the U.S. Food and Drug…”
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Synthesis and SAR studies of very potent imidazopyridine antiprotozoal agents by Biftu, Tesfaye, Feng, Dennis, Fisher, Michael, Liang, Gui-Bai, Qian, Xiaoxia, Scribner, Andrew, Dennis, Richard, Lee, Shuliang, Liberator, Paul A., Brown, Chris, Gurnett, Anne, Leavitt, Penny S., Thompson, Donald, Mathew, John, Misura, Andrew, Samaras, Samantha, Tamas, Tamas, Sina, Joseph F., McNulty, Kathleen A., McKnight, Crystal G., Schmatz, Dennis M., Wyvratt, Matthew

“…Compounds 10a (IC 50 110 pM) and 21 (IC 50 40 pM) are the most potent inhibitors of Eimeria tenella cGMP-dependent protein kinase activity reported to date and…”
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Prevalence of headache in patients with tinnitus by Farzaneh, H., Sina, F.

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Universal Toxicity Gene Signatures for Early Identification of Drug-Induced Tissue Injuries in Rats by Glaab, Warren E, Holder, Daniel, He, Yudong D, Bailey, Wendy J, Gerhold, David L, Beare, Carolann, Erdos, Zoltan, Lane, Pamela, Michna, Laura, Muniappa, Nagaraja, Lawrence, Jeffrey W, Tanis, Keith Q, Sina, Joseph F, Skopek, Thomas R, Sistare, Frank D

“…Abstract A new safety testing paradigm that relies on gene expression biomarker panels was developed to easily and quickly identify drug-induced injuries…”
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Prenatal Ultrasound Diagnosis in 51 Cases of Holoprosencephaly: Craniofacial Anatomy, Associated Malformations, and Genetics by Wenghoefer, M., Anke, M. Ettema, Sina, F., Geipel, A., Kuijpers-Jagtman, A.M., Hansmann, H., Borstlap, W.A., Bergé, S.

“…Objective To analyze the prenatal ultrasound findings of the craniofacial and extracephalic anatomy, the postnatal pathological findings, and the genetic…”
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H1N1--pregnancy as risk factor by Landt, S, Sina, F, Kimmig, R, Schmidt, M

“…There have been repeated reports of a particularly severe course of disease on H1N1 infection in pregnant women. Complemented by a review of the current…”
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A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function by Gerhold, David L, Ozer, Josef S, Dieterle, Frank, Troth, Sean, Perentes, Elias, Cordier, André, Verdes, Pablo, Staedtler, Frank, Mahl, Andreas, Grenet, Olivier, Roth, Daniel R, Wahl, Daniel, Legay, François, Holder, Daniel, Erdos, Zoltan, Vlasakova, Katerina, Jin, Hong, Yu, Yan, Muniappa, Nagaraja, Forest, Tom, Clouse, Holly K, Reynolds, Spencer, Bailey, Wendy J, Thudium, Douglas T, Topper, Michael J, Skopek, Thomas R, Sina, Joseph F, Glaab, Warren E, Vonderscher, Jacky, Maurer, Gérard, Chibout, Salah-Dine, Sistare, Frank D

“…A panel of urinary biomarkers enables the progression of renal injury and subsequent repair and recovery to be monitored after exposure of rats to either…”
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Diagnosis of drug-induced renal tubular toxicity using global gene expression profiles by Jiang, Ying, Gerhold, David L, Holder, Daniel J, Figueroa, David J, Bailey, Wendy J, Guan, Ping, Skopek, Thomas R, Sistare, Frank D, Sina, Joseph F

“…Toxicogenomics can measure the expression of thousands of genes to identify changes associated with drug induced toxicities. It is expected that toxicogenomics…”
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P03.03: Fetal holoprosencephaly—associated malformations and chromosomal disorders by Geipel, A., Sina, F., Knoepfle, G., Germer, U., Hansmann, M., Gembruch, U., Berge, S.

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Genotoxicity of naturally occurring indole compounds: correlation between covalent DNA binding and other genotoxicity tests by Reddy, M. Vijayaraj, Storer, Richard D., Laws, George M., Armstrong, Michael J., Barnum, John E., Gara, Jennifer P., McKnight, Crystal G., Skopek, Thomas R., Sina, Joseph F., DeLuca, John G., Galloway, Sheila M.

“…3‐Methylindole (3MI), melatonin (Mel), serotonin (Ser), and tryptamine (Tryp) were evaluated in vitro for their potential to induce DNA adducts, DNA strand…”
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Trip report by Sina, J F

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Musings by Sina, J F

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Use of real-time gene-specific polymerase chain reaction to measure RNA expression of three family members of rat cytochrome P450 4A by Bleicher, Kimberly B., Pippert, Todd R., Glaab, Warren E., Skopek, Thomas R., Sina, Joseph F., Umbenhauer, Diane R.

“…Exposure of rats to peroxisome proliferators induces members of the cytochrome P450 4A (CYP4A) family. In rats, the CYP4A family consists of four related…”
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Status of animal alternatives for toxicology by Sina, J F

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Genome-wide Linkage Analysis of a Parkinsonian-Pyramidal Syndrome Pedigree by 500 K SNP Arrays by Shojaee, Seyedmehdi, Sina, Farzad, Banihosseini, Setareh Sadat, Kazemi, Mohammad Hossein, Kalhor, Reza, Shahidi, Gholam-Ali, Fakhrai-Rad, Hossein, Ronaghi, Mostafa, Elahi, Elahe

“…Robust SNP genotyping technologies and data analysis programs have encouraged researchers in recent years to use SNPs for linkage studies. Platforms used to…”
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