Search Results - "Simutenko, L V"
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Determination of the Biological Activity of Insulin and Its Analogues in Animals
Published in Vedomosti Naučnogo centra èkspertizy sredstv medicinskogo primeneniâ (Online) (01-07-2023)“…In recent years, there has been a tendency to equate the results of insulin testing by physicochemical methods with its biological activity. However, it should…”
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Calculation of the Median Lethal Dose and Low Lethal Dose Using the CombiStats Biometric Software
Published in Vedomosti Naučnogo centra èkspertizy sredstv medicinskogo primeneniâ (Online) (03-07-2021)“…The median lethal dose (LD 50 ) and low lethal dose (LD 10 ) are calculated in acute toxicity studies, as well as during specific activity assessment of some…”
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Determination of Bacterial Endotoxins in Drugs: False-Negative Results
Published in Pharmaceutical chemistry journal (01-03-2018)“…One of the possible causes of false-negatives in bacterial endotoxin determinations, endotoxin aggregation and adsorption, was examined in a model experiment…”
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4
Development of an Industrial Reference Sample for the Specific Activity of Erythropoietin
Published in Pharmaceutical chemistry journal (01-04-2018)“…On the basis of WHO recommendations and the principles developed for the standardization of erythropoietins we selected one epoetin alfa pharmaceutical…”
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Methodological Approaches to Determination of Depressor Substances in Medicinal Products
Published in Регуляторные исследования и экспертиза лекарственных средств (20-06-2020)“…In order to harmonise national and foreign requirements for quality control of medicinal products, a second variant of the test method, which complies with the…”
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Determination of the Biological Activity of Insulin and Its Analogues in Animals
Published in Vedomosti Naučnogo centra èkspertizy sredstv medicinskogo primeneniâ (Online) (21-09-2022)“…In recent years, there has been a tendency to equate the results of insulin testing by physicochemical methods with its biological activity. However, it should…”
Get full text
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Modern Approaches to Determination of the Biological Activity of Insulin and its
Published in Vedomosti Naučnogo centra èkspertizy sredstv medicinskogo primeneniâ (Online) (05-06-2019)“…The paper considers insulin’s specific action on the patient’s body, types of insulin preparations and insulin analogues which are used for the treatment of…”
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Investigation of the role of prolonged emotional stress in the genesis of hypercholesteremia and hypertension
Published in Neuroscience and behavioral physiology (01-07-1978)“…In experiments on freely moving rabbits, exposed to prolonged (for 2 h) interrupted stimulation of negative emotiogenic zones of the hypothalamus through…”
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Modern Approaches to Determination of the Biological Activity of Insulin and Its Analogues
Published in Регуляторные исследования и экспертиза лекарственных средств (01-06-2019)“…The paper considers insulin’s specific action on the patient’s body, types of insulin preparations and insulin analogues which are used for the treatment of…”
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Disturbances of membrane mechanisms during heart stress damage in rats of different strains
Published in Bulletin of experimental biology and medicine (01-03-1993)Get full text
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Response of the cardiovascular system of cats to ansamycins in the test for depressor substances
Published in Регуляторные исследования и экспертиза лекарственных средств (01-02-2018)“…The article summarises the results of a study which assessed the response of the cardiovascular system of cats to intravenous administration of the ansamycin…”
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Role of emotional stress in disturbances of carbohydrate tolerance
Published in Bulletin of experimental biology and medicine (01-04-1983)Get full text
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Investigation of the role of prolonged emotional stress in the genesis of hypercholesteremia and hypertension
Published in Bulletin of experimental biology and medicine (01-01-1976)Get full text
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Changes in blood cholesterol and triglyceride levels during self-stimulation and avoidance reactions
Published in Bulletin of experimental biology and medicine (01-03-1979)Get full text
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Physiological responses of three lines of rats to stress
Published in Bulletin of experimental biology and medicine (01-08-1992)Get full text
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The physiological reactions to stress in 3 strains of rats
Published in Biulleten' eksperimental'noi biologii i meditsiny (01-07-1992)“…We have studied the resistance of Wistar, August, Fisher male rats to 2- and 24-hours immobilization by vegetative and behavioral reactions. The difference in…”
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The effect of malondialdehyde in the diet of pregnant and lactating female rats on the lipid peroxidation process and physical development of newborn rats
Published in Voprosy pitaniia (01-07-1989)“…Intake of malonic dialdehyde (MDA) with drinking water by pregnant and lactating rats did not result in MDA accumulation in their body or in significant shifts…”
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Effect of stress during pregnancy on the rate of lipid peroxidation in erythrocytes and brain tissue of newborn rats
Published in Bulletin of experimental biology and medicine (01-07-1987)Get full text
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Effect of stress experienced during pregnancy on the rate of lipid peroxidation in erythrocytes and brain tissue of newborn rat pups
Published in Biulleten' eksperimental'noi biologii i meditsiny (01-07-1987)“…The rate of lipid peroxidation (LPO) in erythrocytes and brain homogenate has been assessed by the accumulation of malondialdehyde, the degree of erythrocyte…”
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