Search Results - "Sims, Jennifer K."
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Inhibition of histone binding by supramolecular hosts
Published in Biochemical journal (01-05-2014)“…The tandem PHD (plant homeodomain) fingers of the CHD4 (chromodomain helicase DNA-binding protein 4) ATPase are epigenetic readers that bind either unmodified…”
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Catalytic Function of the PR-Set7 Histone H4 Lysine 20 Monomethyltransferase Is Essential for Mitotic Entry and Genomic Stability
Published in The Journal of biological chemistry (11-07-2008)“…Histone-modifying enzymes play a critical role in modulating chromatin dynamics. In this report we demonstrate that one of these enzymes, PR-Set7, and its…”
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Bivalent recognition of nucleosomes by the tandem PHD fingers of the CHD4 ATPase is required for CHD4-mediated repression
Published in Proceedings of the National Academy of Sciences - PNAS (17-01-2012)“…CHD4 is a catalytic subunit of the NuRD (nucleosome remodeling and deacetylase) complex essential in transcriptional regulation, chromatin assembly and DNA…”
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Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover
Published in BMC cancer (22-04-2014)“…The transcription factor GATA3 is a favorable prognostic indicator in estrogen receptor-α (ERα)-positive breast tumors in which it participates with ERα and…”
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A Trans-tail Histone Code Defined by Monomethylated H4 Lys-20 and H3 Lys-9 Demarcates Distinct Regions of Silent Chromatin
Published in The Journal of biological chemistry (05-05-2006)“…The specific post-translational modifications of the histone proteins are associated with specific DNA-templated processes, such as transcriptional activation…”
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PR-Set7 Establishes a Repressive trans-Tail Histone Code That Regulates Differentiation
Published in Molecular and Cellular Biology (01-07-2008)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Mi-2/NuRD complex function is required for normal S phase progression and assembly of pericentric heterochromatin
Published in Molecular biology of the cell (01-09-2011)“…During chromosome duplication, it is essential to replicate not only the DNA sequence, but also the complex nucleoprotein structures of chromatin. Pericentric…”
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The PR-Set7 binding domain of Riz1 is required for the H4K20me1-H3K9me1 trans-tail 'histone code' and Riz1 tumor suppressor function
Published in Nucleic acids research (01-04-2014)“…PR-Set7/Set8/KMT5a is the sole histone H4 lysine 20 monomethyltransferase (H4K20me1) in metazoans and is essential for proper cell division and genomic…”
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Covalent Modifications of Histone H3K9 Promote Binding of CHD3
Published in Cell reports (Cambridge) (10-10-2017)“…Chromatin remodeling is required for genome function and is facilitated by ATP-dependent complexes, such as nucleosome remodeling and deacetylase (NuRD). Among…”
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Exercise Does Not Influence Myostatin and Follistatin Messenger RNA Expression in Young Women
Published in Journal of strength and conditioning research (01-02-2010)“…Jensky, NE, Sims, JK, Dieli-Conwright, CM, Sattler, FR, Rice, JC, and Schroeder, ET. Exercise does not influence myostatin and follistatin messenger RNA…”
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The influence of eccentric exercise on mRNA expression of skeletal muscle regulators
Published in European journal of applied physiology (01-11-2007)“…To evaluate change in myostatin, follistatin, MyoD and SGT mRNA gene expression using eccentric exercise to study mechanisms of skeletal muscle hypertrophy…”
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Role of the H4K20me1/H3K9me1 trans‐tail histone code in transcriptional regulation
Published in The FASEB journal (01-04-2010)“…We previously discovered a novel trans‐tail histone code in which monomethylated histone H3 lysine 9 (H3K9me1) is enriched in genomic regions containing…”
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Bivalent Recognition of a Single Nucleosome by the Tandem PHD Fingers of CHD4 is Required for CHD4-Mediated Repression
Published in Biophysical journal (31-01-2012)Get full text
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Exercise Does Not Influence Myostatin and Follistatin mRNA expression in Young Women
Published in Journal of strength and conditioning research (01-02-2010)“…We evaluated changes in myostatin, follistatin and MyoD mRNA gene expression using eccentric exercise (EE) and concentric exercise (CE) as probes to better…”
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Catalytic Function of the PR-Set7 Histone H4 Lysine 20 Monomethyltransferase Is Essential for Mitotic Entry and Genomic StabilityS
Published in The Journal of biological chemistry (11-07-2008)“…Histone-modifying enzymes play a critical role in modulating chromatin dynamics. In this report we demonstrate that one of these enzymes, PR-Set7, and its…”
Get full text
Journal Article