Search Results - "Sims, F"

High-fat diet activates liver iPLA2γ generating eicosanoids that mediate metabolic stress by Moon, Sung Ho, Dilthey, Beverly Gibson, Liu, Xinping, Guan, Shaoping, Sims, Harold F., Gross, Richard W.

“…High-fat (HF) diet–induced obesity precipitates multiple metabolic disorders including insulin resistance, glucose intolerance, oxidative stress, and…”
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Cyclooxygenase-2 Mediated Oxidation of 2-Arachidonoyl-Lysophospholipids Identifies Unknown Lipid Signaling Pathways by Liu, Xinping, Moon, Sung Ho, Jenkins, Christopher M, Sims, Harold F, Gross, Richard W

“…Eicosanoid lipids play important roles in cellular signaling as second messengers in inflammation, immune response, vascular tone, and the CNS. Biosynthesis of…”
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Global mRNA selection mechanisms for translation initiation by Costello, Joseph, Castelli, Lydia M, Rowe, William, Kershaw, Christopher J, Talavera, David, Mohammad-Qureshi, Sarah S, Sims, Paul F G, Grant, Christopher M, Pavitt, Graham D, Hubbard, Simon J, Ashe, Mark P

“…The selection and regulation of individual mRNAs for translation initiation from a competing pool of mRNA are poorly understood processes. The closed loop…”
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Spectroscopic and photometric analysis of symbiotic candidates – I. Ten candidates on classical symbiotic stars by Merc, J, Gális, R, Wolf, M, Velez, P, Buil, C, Sims, F, Bohlsen, T, Vrašťák, M, Boussin, C, Boussier, H, Cazzato, P, Diarrasouba, I, Teyssier, F

“…ABSTRACT Symbiotic stars belong to a group of interacting binaries that display a wide variety of phenomena, including prominent outbursts connected with mass…”
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Synthesis of oxidized phospholipids by sn-1 acyltransferase using 2–15-HETE lysophospholipids by Liu, Gao-Yuan, Moon, Sung Ho, Jenkins, Christopher M., Sims, Harold F., Guan, Shaoping, Gross, Richard W.

“…Recently, oxidized phospholipid species have emerged as important signaling lipids in activated immune cells and platelets. The canonical pathway for the…”
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Identification, Cloning, Expression, and Purification of Three Novel Human Calcium-independent Phospholipase A2 Family Members Possessing Triacylglycerol Lipase and Acylglycerol Transacylase Activities by Jenkins, Christopher M, Mancuso, David J, Yan, Wei, Sims, Harold F, Gibson, Beverly, Gross, Richard W

“…Genetic knockout of hormone-sensitive lipase in mice has implicated the presence of other intracellular triacylglycerol (TAG) lipases mediating TAG hydrolysis…”
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Dynamic changes in eIF4F-mRNA interactions revealed by global analyses of environmental stress responses by Costello, Joseph L, Kershaw, Christopher J, Castelli, Lydia M, Talavera, David, Rowe, William, Sims, Paul F G, Ashe, Mark P, Grant, Christopher M, Hubbard, Simon J, Pavitt, Graham D

“…Translation factors eIF4E and eIF4G form eIF4F, which interacts with the messenger RNA (mRNA) 5' cap to promote ribosome recruitment and translation…”
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Dysfunctional cardiac mitochondrial bioenergetic, lipidomic, and signaling in a murine model of Barth syndrome[S] by Kiebish, Michael A., Yang, Kui, Liu, Xinping, Mancuso, David J., Guan, Shaoping, Zhao, Zhongdan, Sims, Harold F., Cerqua, Rebekah, Cade, W. Todd, Han, Xianlin, Gross, Richard W.

“…Barth syndrome is a complex metabolic disorder caused by mutations in the mitochondrial transacylase tafazzin. Recently, an inducible tafazzin shRNA knockdown…”
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Objective Measures of Sleep Apnea and Actigraphy-Based Sleep Characteristics as Correlates of Subjective Sleep Quality in an Epidemiologic Study: The Jackson Heart Sleep Study by Johnson, Dayna A., Javaheri, Sogol, Guo, Na, Champion, Cora L., Sims, Jeraline F., Brock, Michelene P., Sims, Mario, Patel, Sanjay R., Williams, David R., Wilson, James G., Redline, Susan

“…Self-reported "sleep quality" often is assessed in epidemiologic studies. However, the bases for variation in sleep quality is not fully understood. We…”
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Sampling error in eddy correlation flux measurements by Finkelstein, Peter L., Sims, Pamela F.

“…Sampling errors in eddy correlation flux measurements arise from the small number of large eddies that dominate the flux during typical sampling periods…”
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Oxidized fatty acid analysis by charge-switch derivatization, selected reaction monitoring, and accurate mass quantitation by Liu, Xinping, Moon, Sung Ho, Mancuso, David J., Jenkins, Christopher M., Guan, Shaoping, Sims, Harold F., Gross, Richard W.

“…A highly sensitive, specific, and robust method for the analysis of oxidized metabolites of linoleic acid (LA), arachidonic acid (AA), and docosahexaenoic acid…”
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A Fetal Fatty-Acid Oxidation Disorder as a Cause of Liver Disease in Pregnant Women by Ibdah, Jamal A, Bennett, Michael J, Rinaldo, Piero, Zhao, Yiwen, Gibson, Beverly, Sims, Harold F, Strauss, Arnold W

“…Acute fatty liver of pregnancy is a devastating disorder associated with substantial maternal and neonatal morbidity and mortality. 1 – 4 The HELLP syndrome…”
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Lamin B1 maintains the functional plasticity of nucleoli by Martin, Catherine, Chen, Songbi, Maya-Mendoza, Apolinar, Lovric, Josip, Sims, Paul F.G, Jackson, Dean A

“…The dynamic ability of genomes to interact with discrete nuclear compartments appears to be essential for chromatin function. However, the extent to which…”
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The Posteromedial Corner of the Knee: Medial-Sided Injury Patterns Revisited by Sims, William F., Jacobson, Kurt E.

“…Background Medial-sided knee injury patterns have been poorly defined in the available literature. The lack of definition can be attributed to the differing…”
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Glucose depletion inhibits translation initiation via eIF4A loss and subsequent 48S preinitiation complex accumulation, while the pentose phosphate pathway is coordinately up-regulated by Castelli, Lydia M, Lui, Jennifer, Campbell, Susan G, Rowe, William, Zeef, Leo A H, Holmes, Leah E A, Hoyle, Nathaniel P, Bone, Jonathon, Selley, Julian N, Sims, Paul F G, Ashe, Mark P

“…Cellular stress can globally inhibit translation initiation, and glucose removal from yeast causes one of the most dramatic effects in terms of rapidity and…”
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The yeast La related protein Slf1p is a key activator of translation during the oxidative stress response by Kershaw, Christopher J, Costello, Joseph L, Castelli, Lydia M, Talavera, David, Rowe, William, Sims, Paul F G, Ashe, Mark P, Hubbard, Simon J, Pavitt, Graham D, Grant, Chris M

“…The mechanisms by which RNA-binding proteins control the translation of subsets of mRNAs are not yet clear. Slf1p and Sro9p are atypical-La motif containing…”
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Puf3p induces translational repression of genes linked to oxidative stress by Rowe, William, Kershaw, Christopher J, Castelli, Lydia M, Costello, Joseph L, Ashe, Mark P, Grant, Christopher M, Sims, Paul F G, Pavitt, Graham D, Hubbard, Simon J

“…In response to stress, the translation of many mRNAs in yeast can change in a fashion discordant with the general repression of translation. Here, we use…”
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The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation by Castelli, Lydia M, Talavera, David, Kershaw, Christopher J, Mohammad-Qureshi, Sarah S, Costello, Joseph L, Rowe, William, Sims, Paul F G, Grant, Christopher M, Hubbard, Simon J, Ashe, Mark P, Pavitt, Graham D

“…Translation initiation factor eIF4E mediates mRNA selection for protein synthesis via the mRNA 5'cap. A family of binding proteins, termed the 4E-BPs, interact…”
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Effect of IAPP on the proteome of cultured Rin-5F cells by Miraee-Nedjad, Samaneh, Sims, Paul F G, Schwartz, Jean-Marc, Doig, Andrew J

“…Islet amyloid polypeptide (IAPP) or amylin deposits can be found in the islets of type 2 diabetes patients. The peptide is suggested to be involved in the…”
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Quantitative proteomics of the human malaria parasite Plasmodium falciparum and its application to studies of development and inhibition by Nirmalan, Niroshini, Sims, Paul F. G., Hyde, John E.

“…Summary The ability to measure accurately comparative levels of protein expression after drug challenge, metabolic stress, developmental programming or other…”
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