Search Results - "Sims, David E"
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Diversity Within Pericytes
Published in Clinical and Experimental Pharmacology and Physiology (01-10-2000)“…SUMMARY 1. Pericytes are cells of microvessels (arterioles, capillaries and venules) that wrap around endothelial cells. They are most abundant on venules and…”
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Conference Proceeding Journal Article -
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Matrix metalloproteinase‐2 (MMP‐2) is present in the nucleus of cardiac myocytes and is capable of cleaving poly (ADP‐ribose) polymerase (PARP) in vitro
Published in The FASEB journal (01-04-2004)“…Matrix metalloproteinases (MMPs) are traditionally known for their role in extracellular matrix remodeling. Increasing evidence reveals several alternative…”
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Journal Article -
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Susceptibility of rainbow trout Oncorhynchus mykiss, Atlantic salmon Salmo salar and coho salmon Oncorhynchus kisutch to experimental infection with sea lice Lepeophtheirus salmonis
Published in Diseases of aquatic organisms (07-11-2002)“…Physiological, immunological and biochemical parameters of blood and mucus, as well as skin histology, were compared in 3 salmonid species (rainbow trout…”
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Journal Article -
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Heterogeneity of the composition and thickness of tracheal mucus in rats
Published in The American journal of physiology (01-11-1997)“…Inability to preserve airway mucus in situ has limited our understanding of its structure and function. This light- and transmission electron-microscopic study…”
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Journal Article -
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Mechanisms of interleukin-2-induced hepatic toxicity
Published in Cancer research (Chicago, Ill.) (01-02-1996)“…Interleukin 2 (IL-2) mediates the regression of metastatic cancer, but its clinical use is limited by associated toxicities including hepatic dysfunction. To…”
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N omega-nitro-L-arginine methyl ester inhibits inflammatory liver injury induced by interleukin-2
Published in Journal of leukocyte biology (01-01-1998)“…Administration of interleukin‐2 (IL‐2) for treatment of metastatic disease often results in inflammatory liver injury. Previous studies have implicated…”
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Journal Article -
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Interleukin 2 acutely induces platelet and neutrophil-endothelial adherence and macromolecular leakage
Published in Cancer research (Chicago, Ill.) (15-06-1992)“…The acute effects of interleukin 2 (IL-2) were determined in the rat cremaster microcirculation model by intravital, light, and electron microscopy to better…”
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Journal Article -
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Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in C3H/HeN mice
Published in Journal of leukocyte biology (01-07-1996)“…Immunotherapy with interleukin‐2 (IL‐2) is limited by severe side effects thought to be mediated by the activation of immune effector cells and the induction…”
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Effect of emu oil on auricular inflammation induced with croton oil in mice
Published in American journal of veterinary research (01-12-1999)“…To determine the acute anti-inflammatory effects of topically applied emu oil. 96 male CD-1 mice assigned randomly to 4 groups, each comprising 24 mice. To…”
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Differentiation of light-dye effects in the microcirculation
Published in Microvascular research (01-09-1992)“…Activation of photosensitive compounds has been used in the treatment of tumors and as a technique to study various microcirculatory phenomena. This technique…”
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Tumor necrosis factor causes microvascular protein leakage independently of neutrophils or mast cells
Published in The Journal of surgical research (01-06-1994)“…Tumor necrosis factor-alpha (TNF-alpha) has been implicated as an important mediator in the development of multiple system organ failure after either severe…”
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Preservation of tracheal mucus by nonaqueous fixative
Published in Biotechnic & histochemistry (1991)“…Two nonaqueous fixatives, composed of fluorocarbon solvents with dissolved osmium tetroxide, were used to determine the feasibility of preserving the mucous…”
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Journal Article -
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Ultrastructure of pericytes in early stages of histamine-induced inflammation
Published in Journal of morphology (1931) (01-12-1990)“…Physiological and ultrastructural assessment of changes in the walls of venules in the rat cremaster muscle after administration of histamine indicates that…”
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The Effect of Soluble Tumor Necrosis Factor Receptor-II on Endotoxin-Mediated Hemodynamic Instability
Published in The Journal of surgical research (01-01-1995)“…Tumor necrosis factor-α (TNF-α), a central mediator in the hemodynamic response to injury and infection, is a primary mediator of endotoxin-induced hemodynamic…”
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Journal Article Conference Proceeding -
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Limitations of monastral blue as a vascular label: rapid rate of clearance is age-dependent, and interactions with anesthetics depress arterial blood pressure in rats
Published in Microscopy research and technique (01-11-1992)“…Monastral blue (MB) has been described as an inexpensive, nontoxic vascular label. Discrepancies as to its rate of removal from circulation and physiological…”
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Erythrocyte dyscrasia, anemia, and hypothyroidism in chronically underweight llamas
Published in Journal of the American Veterinary Medical Association (01-01-1991)“…A syndrome characterized by anemia, erythrocyte dyscrasia, low body weight, and hypothyroidism was observed in 8 llamas (Lama glama). At initial examination (1…”
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Analysis of relationships between pericytes and gas exchange capillaries in neonatal and mature bovine lungs
Published in Microvascular research (01-01-1983)“…Neonatal and mature bovine lungs were examined ultrastructurally to quantitatively assess pericyte envelopment of gas exchange capillaries and proximities of…”
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Neuro-epitheliomuscular cell and neuro-neuronal gap junctions in Hydra
Published in Journal of neurocytology (01-12-1980)“…Gap junctions have been described ultrastructurally between neurons and epitheliomuscular cells and between neurons and their processes in the hypostome,…”
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