Search Results - "Simpson, J A"

Adverse effects of falciparum and vivax malaria and the safety of antimalarial treatment in early pregnancy: a population-based study by McGready, R, Dr, Lee, SJ, PhD, Wiladphaingern, J, Ashley, EA, MBBS, Rijken, MJ, MD, Boel, M, MD, Simpson, JA, PhD, Paw, MK, Pimanpanarak, M, Mu, Oh, Singhasivanon, P, Prof, White, NJ, Prof, Nosten, FH, Prof

“…Summary Background The effects of malaria and its treatment in the first trimester of pregnancy remain an area of concern. We aimed to assess the outcome of…”
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The relationship between perceived stigma, disclosure patterns, support and distress in new attendees at an infertility clinic by Slade, P., O'Neill, C., Simpson, A.J., Lashen, H.

“…BACKGROUND A model suggesting that high perception of stigma is associated with reduced disclosure to others, leading to lower social support and higher…”
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Longitudinal diffusion tensor imaging in frontotemporal dementia by Mahoney, Colin J., Simpson, Ivor J. A., Nicholas, Jennifer M., Fletcher, Phillip D., Downey, Laura E., Golden, Hannah L., Clark, Camilla N., Schmitz, Nicole, Rohrer, Jonathan D., Schott, Jonathan M., Zhang, Hui, Ourselin, Sebastian, Warren, Jason D., Fox, Nick C.

“…Objective Novel biomarkers for monitoring progression in neurodegenerative conditions are needed. Measurement of microstructural changes in white matter (WM)…”
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Validation of the DECAF score to predict hospital mortality in acute exacerbations of COPD by Echevarria, C, Steer, J, Heslop-Marshall, K, Stenton, S C, Hickey, P M, Hughes, R, Wijesinghe, M, Harrison, R N, Steen, N, Simpson, A J, Gibson, G J, Bourke, S C

“…Hospitalisation due to acute exacerbations of COPD (AECOPD) is common, and subsequent mortality high. The DECAF score was derived for accurate prediction of…”
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Malaria and immunity during pregnancy and postpartum: a tale of two species by McLean, A R D, Ataide, R, Simpson, J A, Beeson, J G, Fowkes, F J I

“…It is well established that pregnant women are at an increased risk of Plasmodium falciparum infection when compared to non-pregnant individuals and limited…”
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Measuring cortical mean diffusivity to assess early microstructural cortical change in presymptomatic familial Alzheimer’s disease by Weston, Philip S. J., Poole, Teresa, Nicholas, Jennifer M., Toussaint, Nicolas, Simpson, Ivor J. A., Modat, Marc, Ryan, Natalie S., Liang, Yuying, Rossor, Martin N., Schott, Jonathan M., Ourselin, Sebastien, Zhang, Hui, Fox, Nick C.

“…Abstract Background There is increasing interest in improving understanding of the timing and nature of early neurodegeneration in Alzheimer’s disease (AD) and…”
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Successful use of feedback to improve antibiotic prescribing and reduce Clostridium difficile infection: a controlled interrupted time series by Fowler, S., Webber, A., Cooper, B. S., Phimister, A., Price, K., Carter, Y., Kibbler, C. C., Simpson, A. J. H., Stone, S. P.

“…Objectives To investigate the effect of reinforcing a narrow-spectrum antibiotic policy on antibiotic prescription and Clostridium difficile infection (CDI)…”
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health benefits of omega-3 polyunsaturated fatty acids: a review of the evidence by Ruxton, C.H.S, Reed, S.C, Simpson, M.J.A, Millington, K.J

“…The UK dietary guidelines for cardiovascular disease acknowledge the importance of long-chain omega-3 polyunsaturated fatty acids (PUFA) - a component of fish…”
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Thrombocytosis helps to stratify risk of colorectal cancer in patients referred on a 2-week-wait pathway by Bailey, J. A., Hanbali, N., Premji, K., Bunce, J., Mashlab, S., Simpson, J. A., Humes, D. J., Banerjea, A.

“…Purpose Primary care studies suggest that thrombocytosis (platelet counts > 400 × 10 9 /L) is associated with an increased risk of colorectal cancer (CRC). We…”
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Social regulation of adult neurogenesis in a eusocial mammal by Peragine, D.E, Simpson, J.A, Mooney, S.J, Lovern, M.B, Holmes, M.M

“…Highlights • We examined social and gonadal control of adult neurogenesis in a eusocial rodent. • Dominant breeders have fewer DCX(+) cells in the DG, PCx, and…”
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Parasite Strain, Host Immunity, and Circulating Blood Cells with Dead Parasites: Why Predicting Malaria Parasite Clearance Is Not a Simple Task by Simpson, J A, McCaw, J, Fowkes, F J

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Recombinant (F1 + V) vaccine protects cynomolgus macaques against pneumonic plague by Williamson, E.D, Packer, P.J, Waters, E.L, Simpson, A.J, Dyer, D, Hartings, J, Twenhafel, N, Pitt, M.L.M

“…Abstract Cynomolgus macaques, immunised at the 80 μg dose level with an rF1 + rV vaccine (two doses, three weeks apart), were fully protected against pneumonic…”
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Sequential exhaustive extraction of a Mollisol soil, and characterizations of humic components, including humin, by solid and solution state NMR by Song, G., Novotny, E. H., Simpson, A. J., Clapp, C. E., Hayes, M. H. B.

“…Summary A comprehensive sequential extraction procedure was applied to isolate soil organic components using aqueous solvents at different pH values, base plus…”
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Statistical approaches for assessing the relative validity of a food-frequency questionnaire: use of correlation coefficients and the kappa statistic by Masson, LF, MCNeill, G, Tomany, JO, Simpson, JA, Peace, HS, Wei, L, Grubb, DA, Bolton-Smith, C

“…Objective: To compare different statistical methods for assessing the relative validity of a self-administered, 150-item, semi-quantitative food-frequency…”
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Bioinformatics construction of the human cell surfaceome by da Cunha, J.P.C, Galante, P.A.F, de Souza, J.E, de Souza, R.F, Carvalho, P.M, Ohara, D.T, Moura, R.P, Oba-Shinja, S.M, Marie, S.K.N, Silva, W.A. Jr, Perez, R.O, Stransky, B, Pieprzyk, M, Moore, J, Caballero, O, Gama-Rodrigues, J, Habr-Gama, A, Kuo, W.P, Simpson, A.J, Camargo, A.A, Old, Lloyd J, de Souza, S.J

“…Cell surface proteins are excellent targets for diagnostic and therapeutic interventions. By using bioinformatics tools, we generated a catalog of 3,702…”
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Ensemble Learning Incorporating Uncertain Registration by Simpson, I. J. A., Woolrich, M. W., Andersson, J. L. R., Groves, A. R., Schnabel, J. A.

“…This paper proposes a novel approach for improving the accuracy of statistical prediction methods in spatially normalized analysis. This is achieved by…”
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Evaluation of the effect of diagnostic methodology on the reported incidence of ventilator-associated pneumonia by Morris, A Conway, Kefala, K, Simpson, A J, Wilkinson, T S, Everingham, K, Kerslake, D, Raby, S, Laurenson, I F, Swann, D G, Walsh, T S

“…The optimal method for diagnosing ventilator-associated pneumonia (VAP) is controversial and its effect on reported incidence uncertain. This study aimed to…”
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Diagnosing ventilator-associated pneumonia (VAP) in UK NHS ICUs: the perceived value and role of a novel optical technology by Jones, W S, Suklan, J, Winter, A, Green, K, Craven, T, Bruce, A, Mair, J, Dhaliwal, K, Walsh, T, Simpson, A J, Graziadio, S, Allen, A J

“…Diagnosing ventilator-associated pneumonia (VAP) in an intensive care unit (ICU) is a complex process. Our aim was to collect, evaluate and represent the…”
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Whole genome sequencing reveals genomic heterogeneity and antibiotic purification in Mycobacterium tuberculosis isolates by Black, P A, de Vos, M, Louw, G E, van der Merwe, R G, Dippenaar, A, Streicher, E M, Abdallah, A M, Sampson, S L, Victor, T C, Dolby, T, Simpson, J A, van Helden, P D, Warren, R M, Pain, A

“…Whole genome sequencing has revolutionised the interrogation of mycobacterial genomes. Recent studies have reported conflicting findings on the genomic…”
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Early clinical experiences with nintedanib in three UK tertiary interstitial lung disease centres by Toellner, Hannah, Hughes, G., Beswick, W., Crooks, M. G., Donaldson, C., Forrest, I., Hart, S. P., Leonard, C., Major, M., Simpson, A. J., Chaudhuri, N.

“…Background Nintedanib has been shown to slow disease progression in patients with idiopathic pulmonary fibrosis (IPF). It was approved by the National…”
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