Search Results - "Simpson, George M"

The introduction of clozapine at the Nathan Kline Institute in New York and its long-term consequences by de Leon, Jose, Wang, Linda, Simpson, George M.

“…Nathan S. Kline was a pioneer in psychopharmacology in the United States (US). In 1952, Kline started a research unit at Rockland State Hospital, New York…”
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Clozapine: more side effects but still the best antipsychotic by Kang, Xin, Simpson, George M

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The apparent effects of ziprasidone on plasma lipids and glucose by KINGSBURY, Steven J, FAYEK, Mohamed, TRUFASIU, Dorina, ZADA, Jaafar, SIMPSON, George M

“…We examined the effects of ziprasidone on body mass index (BMI) and serum levels of glucose, cholesterol, and triglycerides. As part of a multicenter study…”
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Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia by Evgrafov, Oleg V., Armoskus, Chris, Wrobel, Bozena B., Spitsyna, Valeria N., Souaiaia, Tade, Herstein, Jennifer S., Walker, Christopher P., Nguyen, Joseph D., Camarena, Adrian, Weitz, Jonathan R., Kim, Jae Mun “Hugo”, Lopez Duarte, Edder, Wang, Kai, Simpson, George M., Sobell, Janet L., Medeiros, Helena, Pato, Michele T., Pato, Carlos N., Knowles, James A.

“…Genome-wide association studies of schizophrenia have demonstrated that variations in noncoding regions are responsible for most of the common variation…”
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Double-Blind Study of Clozapine Dose Response in Chronic Schizophrenia by Simpson, George M., Josiassen, Richard C., Stanilla, Joseph K., de Leon, Jose, Nair, Chand, Abraham, George, Odom-White, Aruby, Turner, Ralph M.

“…OBJECTIVE: This study explored the relative efficacy of three different doses of clozapine. METHOD: Fifty patients who met Kane et al.'s criteria for…”
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Randomized, controlled, double-blind multicenter comparison of the efficacy and tolerability of ziprasidone and olanzapine in acutely iii inpatients with schizophrenia or schizoaffective disorder by SIMPSON, George M, GLICK, Ira D, WEIDEN, Peter J, ROMANO, Steven J, SIU, Cynthia O

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Maintenance therapy with once-monthly administration of long-acting injectable risperidone in patients with schizophrenia or schizoaffective disorder: a pilot study of an extended dosing interval by Gharabawi, Georges M, Gearhart, Natalie C, Lasser, Robert A, Mahmoud, Ramy A, Zhu, Young, Mannaert, Erik, Naessens, Ineke, Bossie, Cynthia A, Kujawa, Mary, Simpson, George M

“…Several clinical studies have established the efficacy, safety, and tolerability of long-acting risperidone administered once every 2 weeks in patients with…”
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The National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project: schizophrenia trial design and protocol development by Stroup, T Scott, McEvoy, Joseph P, Swartz, Marvin S, Byerly, Matthew J, Glick, Ira D, Canive, Jose M, McGee, Mark F, Simpson, George M, Stevens, Michael C, Lieberman, Jeffrey A

“…The National Institute of Mental Health initiated the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) program to evaluate the effectiveness…”
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A 1-year double-blind study of 2 doses of long-acting risperidone in stable patients with schizophrenia or schizoaffective disorder by SIMPSON, George M, MAHMOUD, Ramy A, LASSER, Robert A, KUJAWA, Mary, BOSSIE, Cynthia A, TURKOZ, Ibrahim, RODRIGUEZ, Steven, GHARABAWI, Georges M

“…This study examined the effects of 2 doses of long-acting risperidone injection in patients with schizophrenia or schizoaffective disorder. This 52-week,…”
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Weight gain during a double-blind multidosage clozapine study by DE LEON, Jose, DIAZ, Francisco J, JOSIASSEN, Richard C, COOPER, Thomas B, SIMPSON, George M

“…Possible variables associated with weight gain during clozapine treatment include dosing, treatment duration, baseline body mass index (BMI), sex, and plasma…”
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Effectiveness of Switching to ziprasidone for Stable but symptomatic outpatients with schizophrenia by WEIDEN, Peter J, SIMPSON, George M, POTKIN, Steven G, O'SULLIVAN, Richard L

“…Many outpatients with schizophrenia experience persistent symptoms or side effects on their current antipsychotic regimen. Few studies have prospectively…”
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Risperidone liquid concentrate and Oral lorazepam versus intramuscular haloperidol and intramuscular lorazepam for treatment of psychotic agitation by CURRIER, Glenn W, SIMPSON, George M

“…Although agitation associated with psychosis is a common presentation in the psychiatric emergency service, there is no consensus concerning the best…”
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Six-Month, Blinded, Multicenter Continuation Study of Ziprasidone Versus Olanzapine in Schizophrenia by Simpson, George M., Weiden, Peter, Pigott, Theresa, Murray, Stephen, Siu, Cynthia O., Romano, Steven J.

“…OBJECTIVE: The authors' goal was to compare the efficacy and tolerability of 6 months' treatment with flexible-dose ziprasidone and olanzapine in patients with…”
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Paliperidone extended-release tablets in schizophrenia patients previously treated with risperidone by Canuso, Carla M, Youssef, Eriene A, Bossie, Cynthia A, Turkoz, Ibrahim, Schreiner, Andreas, Simpson, George M

“…To assess the effect of paliperidone extended-release (ER) tablets in patients with acute symptoms who had previously received risperidone. Data for this…”
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Long-Term Improvement in Efficacy and Safety After Switching to Ziprasidone in Stable Outpatients with Schizophrenia by Simpson, George M., O'Gorman, Cedric J., Loebel, Antony, Yang, Ruoyong

“…The long-term efficacy and tolerability of treatment with ziprasidone following a switch from prior antipsychotics was evaluated in outpatients with…”
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Review of antipsychotics in children and adolescents by Kapetanovic, Suad, Simpson, George M

“…The use of antipsychotics in children and adolescents in the clinical setting is increasing. This article reviews 77 clinical trials published in the last 10…”
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Atypical antipsychotics and the burden of disease by Simpson, George M

“…The atypical antipsychotics are defined by improved tolerability in comparison with conventional antipsychotics. Specifically, the atypicals are substantially…”
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Improvement in cognitive function following a switch to ziprasidone from conventional antipsychotics, olanzapine, or risperidone in outpatients with schizophrenia by Harvey, Philip D, Meltzer, Herbert, Simpson, George M, Potkin, Steven G, Loebel, Antony, Siu, Cynthia, Romano, Steven J

“…Objective: To assess changes in cognitive function in stable outpatients with schizophrenia switched to ziprasidone from conventional antipsychotics ( n=108),…”
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An 8-week open-label trial of a 6-day course of mifepristone for the treatment of psychotic depression by SIMPSON, George M, SHESHAI, Adel El, LOZA, Nasser, KINGSBURY, Steven J, FAYEK, Mohamed, RADY, Ahmed, FAWZY, Waleed

“…Several investigations suggest that mifepristone leads to the rapid amelioration of psychotic depression. However, these studies were of short duration (1 week…”
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Cross-cultural psychopharmacology: a current clinical perspective by Pi, Edmond H, Simpson, George M

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