Search Results - "Simpson, G. J"

Genome-wide analysis of cancer/testis gene expression by Hofmann, Oliver, Caballero, Otavia L, Stevenson, Brian J, Chen, Yao-Tseng, Cohen, Tzeela, Chua, Ramon, Maher, Christopher A, Panji, Sumir, Schaefer, Ulf, Kruger, Adele, Lehvaslaiho, Minna, Carninci, Piero, Hayashizaki, Yoshihide, Jongeneel, C. Victor, Simpson, Andrew J.G, Old, Lloyd J, Hide, Winston

“…Cancer/Testis (CT) genes, normally expressed in germ line cells but also activated in a wide range of cancer types, often encode antigens that are immunogenic…”
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Cancer/testis antigens, gametogenesis and cancer by Simpson, Andrew J. G, Caballero, Otavia L, Jungbluth, Achim, Chen, Yao-Tseng, Old, Lloyd J

“…Cancer/testis (CT) antigens, of which more than 40 have now been identified, are encoded by genes that are normally expressed only in the human germ line, but…”
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Rational Design of Indoleamine 2,3-Dioxygenase Inhibitors by Röhrig, Ute F, Awad, Loay, Grosdidier, Aurélien, Larrieu, Pierre, Stroobant, Vincent, Colau, Didier, Cerundolo, Vincenzo, Simpson, Andrew J. G, Vogel, Pierre, Van den Eynde, Benoît J, Zoete, Vincent, Michielin, Olivier

“…Indoleamine 2,3-dioxygenase (IDO) is an important therapeutic target for the treatment of diseases such as cancer that involve pathological immune escape. We…”
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Differential evolution of MAGE genes based on expression pattern and selection pressure by Zhao, Qi, Caballero, Otavia L, Simpson, Andrew J G, Strausberg, Robert L

“…Starting from publicly-accessible datasets, we have utilized comparative and phylogenetic genome analyses to characterize the evolution of the human MAGE gene…”
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Selective Imaging of Active Pharmaceutical Ingredients in Powdered Blends with Common Excipients Utilizing Two-Photon Excited Ultraviolet-Fluorescence and Ultraviolet-Second Order Nonlinear Optical Imaging of Chiral Crystals by Toth, S. J, Madden, J. T, Taylor, L. S, Marsac, P, Simpson, G. J

“…Second order nonlinear optical imaging of chiral crystals (SONICC) and two-photon excited fluorescence measurements [both autofluorescence and two-photon…”
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MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines by BING YANG, O'HERRIN, Sean M, HONGZHUANG PENG, IVANOV, Alexey V, SIMPSON, Andrew J. G, LONGLEY, B. Jack, JIANQIANG WU, REAGAN-SHAW, Shannon, YONGSHENG MA, BHAT, Kumar M. R, GRAVEKAMP, Claudia, SETALURI, Vijayasaradhi, PETERS, Noel, HOFFMANN, F. Michael

“…The MAGE-A, MAGE-B, and MAGE-C protein families comprise the class-I MAGE/cancer testes antigens, a group of highly homologous proteins whose expression is…”
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Transcriptome-guided characterization of genomic rearrangements in a breast cancer cell line by Zhao, Qi, Caballero, Otavia L, Levy, Samuel, Stevenson, Brian J, Iseli, Christian, de Souza, Sandro J, Galante, Pedro A, Busam, Dana, Leversha, Margaret A, Chadalavada, Kalyani, Rogers, Yu-Hui, Venter, J. Craig, Simpson, Andrew J.G, Strausberg, Robert L

“…We have identified new genomic alterations in the breast cancer cell line HCC1954, using high-throughput transcriptome sequencing. With 120 Mb of cDNA…”
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Single Particle Nonlinear Optical Imaging of Trace Crystallinity in an Organic Powder by Wanapun, D, Kestur, U.S, Taylor, L. S, Simpson, G. J

“…Microscopic characterization of crystallinity in powders can reveal information lost in ensemble-averaged measurements. Nonlinear optical imaging based on…”
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Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma by Valsesia, Armand, Rimoldi, Donata, Martinet, Danielle, Ibberson, Mark, Benaglio, Paola, Quadroni, Manfredo, Waridel, Patrice, Gaillard, Muriel, Pidoux, Mireille, Rapin, Blandine, Rivolta, Carlo, Xenarios, Ioannis, Simpson, Andrew J G, Antonarakis, Stylianos E, Beckmann, Jacques S, Jongeneel, C Victor, Iseli, Christian, Stevenson, Brian J

“…Cancer genomes frequently contain somatic copy number alterations (SCNA) that can significantly perturb the expression level of affected genes and thus disrupt…”
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Transferable anticancer innate immunity in spontaneous regression/complete resistance mice by Hicks, Amy M, Riedlinger, Gregory, Willingham, Mark C, Alexander-Miller, Martha A, Von Kap-Herr, C, Pettenati, Mark J, Sanders, Anne M, Weir, Holly M, Du, Wei, Kim, Joseph, Simpson, Andrew J G, Old, Lloyd J, Cui, Zheng

“…Spontaneous regression/complete resistance (SR/CR) mice resist very high doses of cancer cells that are lethal to WT mice even at low doses. In this study, we…”
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Sequence Survey of Receptor Tyrosine Kinases Reveals Mutations in Glioblastomas by Rand, Vikki, Huang, Jiaqi, Stockwell, Tim, Ferriera, Steve, Buzko, Oleksandr, Levy, Samuel, Busam, Dana, Li, Kelvin, Edwards, Jennifer B., Eberhart, Charles, Murphy, Kathleen M., Tsiamouri, Alexia, Beeson, Karen, Andrew J. G. Simpson, Venter, J. Craig, Riggins, Gregory J., Strausberg, Robert L.

“…It is now clear that tyrosine kinases represent attractive targets for therapeutic intervention in cancer. Recent advances in DNA sequencing technology now…”
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CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens by Almeida, Luiz Gonzaga, Sakabe, Noboru J, deOliveira, Alice R, Silva, Maria Cristina C, Mundstein, Alex S, Cohen, Tzeela, Chen, Yao-Tseng, Chua, Ramon, Gurung, Sita, Gnjatic, Sacha, Jungbluth, Achim A, Caballero, Otávia L, Bairoch, Amos, Kiesler, Eva, White, Sarah L, Simpson, Andrew J.G, Old, Lloyd J, Camargo, Anamaria A, Vasconcelos, Ana Tereza R

“…The potency of the immune response has still to be harnessed effectively to combat human cancers. However, the discovery of T-cell targets in melanomas and…”
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Humanized Lewis-Y Specific Antibody Based Delivery of STAT3 siRNA by Ma, Yuelong, Kowolik, Claudia M, Swiderski, Piotr M, Kortylewski, Marcin, Yu, Hua, Horne, David A, Jove, Richard, Caballero, Otavia L, Simpson, Andrew J. G, Lee, Fook-Thean, Pillay, Vinochani, Scott, Andrew M

“…The clinical application of siRNA is limited largely by the lack of efficient, cell-specific delivery systems. Antibodies are attractive delivery vehicles for…”
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Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data by Grigoriadis, Anita, Mackay, Alan, Reis-Filho, Jorge S, Steele, Dawn, Iseli, Christian, Stevenson, Brian J, Jongeneel, C Victor, Valgeirsson, Haukur, Fenwick, Kerry, Iravani, Marjan, Leao, Maria, Simpson, Andrew J G, Strausberg, Robert L, Jat, Parmjit S, Ashworth, Alan, Neville, A Munro, O'Hare, Michael J

“…Diverse microarray and sequencing technologies have been widely used to characterise the molecular changes in malignant epithelial cells in breast cancers…”
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Identification of Cancer/Testis-Antigen Genes by Massively Parallel Signature Sequencing by Chen, Yao-Tseng, Scanlan, Matthew J., Venditti, Charis A., Chua, Ramon, Theiler, Gregory, Stevenson, Brian J., Iseli, Christian, Gure, Ali O., Vasicek, Tom, Strausberg, Robert L., Jongeneel, C. Victor, Old, Lloyd J., Andrew J. G. Simpson

“…Massively parallel signature sequencing (MPSS) generates millions of short sequence tags corresponding to transcripts from a single RNA preparation. Most MPSS…”
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CT-X antigen expression in human breast cancer by Grigoriadis, Anita, Caballero, Otavia L, Hoek, Keith S, da Silva, Leonard, Chen, Yao-Tseng, Shin, Sandra J, Jungbluth, Achim A, Miller, Lance D, Clouston, David, Cebon, Jonathan, Old, Lloyd J, Lakhani, Sunil R, Simpson, Andrew J.G, Neville, A. Munro

“…Cancer/testis (CT) genes are predominantly expressed in human germ line cells, but not somatic tissues, and frequently become activated in different cancer…”
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The Spontaneous CD8+ T-Cell Response to HLA-A2-Restricted NY-ESO-1b Peptide in Hepatocellular Carcinoma Patients by Shang, Xiao-Ying, Chen, Hong-Song, Zhang, Hua-Gang, Pang, Xue-Wen, Qiao, Huan, Peng, Ji-Run, Qin, Li-Ling, Fei, Ran, Mei, Ming-Hui, Leng, Xi-Sheng, Gnjatic, Sacha, Ritter, Gerd, Simpson, Andrew J G, Old, Lloyd J, Chen, Wei-Feng

“…Purpose: Hepatocellular carcinoma (HCC) can express various cancer-testis antigens including NY-ESO-1, members of the SSX family, members of the MAGE family,…”
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Characterization of a Cancer/Testis (CT) Antigen Gene Family Capable of Eliciting Humoral Response in Cancer Patients by Parmigiani, Raphael B., Bettoni, Fabiana, Vibranovski, Maria D., Lopes, Marilene H., Martins, Waleska K., Cunha, Isabela W., Soares, Fernando A., Simpson, Andrew J. G., de Souza, Sandro J., Camargo, Anamaria A.

“…Cancer/testis (CT) antigens are immunogenic proteins expressed in normal gametogenic tissues and in different types of tumors. CT antigens are promising…”
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HPtaa database-potential target genes for clinical diagnosis and immunotherapy of human carcinoma by Wang, Xiaosong, Zhao, Haitao, Xu, Qingwen, Jin, Weibo, Liu, Changning, Zhang, Huagang, Huang, Zhibin, Zhang, Xinyu, Zhang, Yu, Xin, Dianqi, Simpson, Andrew J. G, Old, Lloyd J, Na, Yanqun, Zhao, Yi, Chen, Weifeng

“…Tumor-associated antigens (TAAs) have been the most actively employed targets in the clinical diagnosis and treatment of human carcinoma, such as PSA in the…”
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Rabies vaccine is associated with decreased all-cause mortality in dogs by Knobel, Darryn L, Arega, Sintayehu, Reininghaus, Bjorn, Simpson, Gregory J.G, Gessner, Bradford D, Stryhn, Henrik, Conan, Anne

“…Highlights • Rabies vaccine has a strong protective effect against all-cause mortality in dogs. • The effect is present across all age groups, but weakens with…”
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