Search Results - "Simpson, F J"

Benign transport of breast epithelium into axillary lymph nodes after biopsy by CARTER, B. A, JENSEN, R. A, SIMPSON, J. F, PAGE, D. L

“…The most important prognostic indicator of distant metastasis in breast cancer is histologic documentation of axillary lymph node metastasis. Controversy…”
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Metaplastic breast tumors with a dominant fibromatosis‐like phenotype have a high risk of local recurrence by Gobbi, Helenice, Simpson, Jean F., Borowsky, Alexander, Jensen, Roy A., Page, David L.

“…BACKGROUND In the current study the authors describe the clinicopathologic characteristics of a low grade variant of spindle cell metaplastic tumors of the…”
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Mice transgenic for human carcinoembryonic antigen as a model for immunotherapy by CLARKE, P, MANN, J, SIMPSON, J. F, RICKARD-DICKSON, K, PRIMUS, F. J

“…Mice transgenic for the human carcinoembryonic antigen (CEA) gene were prepared for use as a preclinical model for immunotherapy. A 32.6-kb fragment containing…”
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Amplification of CCND1 and expression of its protein product, cyclin D1, in ductal carcinoma in situ of the breast by Simpson, JF, Quan, DE, O'Malley, F, Odom-Maryon, T, Clarke, PE

“…Ductal carcinoma in situ (DCIS) of the breast is a heterogeneous disease clinically and biologically. The few available studies of its natural history…”
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Transforming growth factor-β and breast cancer risk in Women with mammary epithelial hyperplasia by GOBBI, H, DUPONT, W. D, SIMPSON, J. F, PLUMMER, W. D, SCHUYLER, P. A, OLSON, S. J, ARTEAGA, C. L, PAGE, D. L

“…Transforming growth factors-beta (TGF-betas) regulate mammary epithelial cell division. Loss of expression of TGF-beta receptor II (TGF-beta-RII) is related to…”
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Diabetic mastopathy : A clinicopathologic review by ELY, K. A, TSE, G, SIMPSON, J. F, CLARFELD, R, PAGE, D. L

“…Diabetic mastopathy, an uncommon form of lymphocytic mastitis and stromal fibrosis, typically occurs in longstanding type 1 diabetes. Nineteen cases meeting…”
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Non-Hodgkin's lymphoma involving the breast by Arber, D A, Simpson, J F, Weiss, L M, Rappaport, H

“…Breast involvement by non-Hodgkin's lymphoma is rare. Differences between primary and secondary breast lymphoma have been reported, and a relationship between…”
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Predictors of long-term outcome following high-dose chemotherapy in high-risk primary breast cancer by SOMLO, G, SIMPSON, J. F, KOGUT, N, MCNAMARA, M, MOLINA, A, SOMLO, E, DOROSHOW, J. H, FRANKEL, P, CHOW, W, LEONG, L, MARGOLIN, K, MORGAN, R. JR, RASCHKO, J, SHIBATA, S, FORMAN, S

“…We report on a predictive model of long-term outcome in 114 high-risk breast cancer patients treated with high-dose chemotherapy between 1989 and 1994…”
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p27/Kip1 mutation found in breast cancer by SPIRIN, K. S, SIMPSON, J. F, TAKEUCHI, S, KAWAMATA, N, MILLER, C. W, KOEFFLER, H. P

“…The p27/Kip1 protein belongs to the recently identified family of proteins called cyclin-dependent kinase inhibitors. These proteins play an important role as…”
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Abnormalities detected on transvaginal ultrasonography in tamoxifen-treated postmenopausal breast cancer patients may represent endometrial cystic atrophy by McGonigle, Kathryn F., Shaw, Sara L., Vasilev, Steven A., Odom-Maryon, Tamara, Roy, Subir, Simpson, Jean F.

“…OBJECTIVE: This study was conducted to examine the histopathologic changes in tamoxifen-treated postmenopausal patients with endometrial thickness ≥5 mm with…”
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Loss of expression of transforming growth factor beta type II receptor correlates with high tumour grade in human breast in-situ and invasive carcinomas by Gobbi, H, Arteaga, C L, Jensen, R A, Simpson, J F, Dupont, W D, Olson, S J, Schuyler, P A, Plummer, Jr, W D, Page, D L

“…Aims Loss of transforming growth factor beta type II receptor (TGFβ‐RII) expression has been associated with resistance to TGFβ‐mediated inhibition of cell…”
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Cardiac mitochondrial DNA polymerase-γ is inhibited competitively and noncompetitively by phosphorylated zidovudine by LEWIS, W, SIMPSON, J. F, MEYER, R. R

“…Zidovudine (azidothymidine [AZT]) inhibits human immunodeficiency virus replication and reduces the severity of acquired immunodeficiency syndrome. A limiting…”
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Use of cultured cells as a control for quantitative immunocytochemical analysis of estrogen receptor in breast cancer: The Quicgel method by RIERA, J, SIMPSON, J. F, TAMAYO, R, BATTIFORA, H, MD

“…Variation in tissue fixation, processing, and staining is largely responsible for poor reproducibility of estrogen receptor (ER) immunohistochemistry assays. A…”
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Lobular neoplasia of the breast: higher risk for subsequent invasive cancer predicted by more extensive disease by Page, D L, Kidd, Jr, T E, Dupont, W D, Simpson, J F, Rogers, L W

“…We have stratified the cancer risk implications of lobular pattern in situ neoplasias of the breast by separating marked examples of this histologic spectrum…”
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Endothelial area as a prognostic indicator for invasive breast carcinoma by Simpson, Jean F., Ahn, Chul, Battifora, Hector, Esteban, Jose M.

“…BACKGROUND Vascular enumeration using antibodies to Factor VIII has been reported to be an independent prognostic indicator of invasive breast carcinoma…”
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Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo by MOULDER, Stacy L, YAKES, F. Michael, MUTHUSWAMY, Senthil K, BIANCO, Roberto, SIMPSON, Jean F, ARTEAGA, Carlos L

“…Aberrrant signaling by the epidermal growth factor receptor [EGFR (HER1, erbB1)] and/or HER2/neu tyrosine kinases is present in a cohort of breast carcinomas…”
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Expression of mitoses per thousand cells and cell density in breast carcinomas: a proposal by Simpson, J F, Dutt, P L, Page, D L

“…A method of standardizing mitotic counts is described. This provisional approach, which expresses mitoses as a percentage of breast cancer cells present, holds…”
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Maintenance of polarity and a dual cell population in adenoid cystic carcinoma of the breast: an immunohistochemical study by KASAMI, M, OLSON, S. J, SIMPSON, J. F, PAGE, D. L

“…Aims: Adenoid cystic carcinoma (ACC) of the breast, although quite uncommon, is histologically distinct and has an excellent prognosis. Our purpose was to…”
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Expression of biliary glycoprotein (CD66a) in normal and malignant breast epithelial cells by Huang, J, Simpson, J F, Glackin, C, Riethorf, L, Wagener, C, Shively, J E

“…Biliary glycoprotein (BGP, CD66a, or C-CAM-1) is a cell adhesion glycoprotein expressed in colon, liver, and hematopoietic tissues. Four major isoforms (a-d)…”
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Advantage of dose fractionation in monoclonal antibody-targeted radioimmunotherapy by Schlom, J, Molinolo, A, Simpson, J F, Siler, K, Roselli, M, Hinkle, G, Houchens, D P, Colcher, D

“…Monoclonal antibody (MAb) B72.3 IgG was radiolabeled with 131I and administered to female athymic NCr-nu mice bearing the LS-174T human colon adenocarcinoma…”
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