Search Results - "Simpson, Ericka P."

Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial by Wills, Anne-Marie, Dr, Hubbard, Jane, RD, Macklin, Eric A, PhD, Glass, Jonathan, Prof, Tandan, Rup, Prof, Simpson, Ericka P, MD, Brooks, Benjamin, Prof, Gelinas, Deborah, MD, Mitsumoto, Hiroshi, Prof, Mozaffar, Tahseen, Prof, Hanes, Gregory P, MD, Ladha, Shafeeq S, MD, Heiman-Patterson, Terry, Prof, Katz, Jonathan, MD, Lou, Jau-Shin, MD, Mahoney, Katy, BA, Grasso, Daniela, BA, Lawson, Robert, BS, Yu, Hong, MS, Cudkowicz, Merit, Prof

“…Summary Background Amyotrophic lateral sclerosis is a fatal neurodegenerative disease with few therapeutic options. Mild obesity is associated with greater…”
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Whole-Genome Analysis of Sporadic Amyotrophic Lateral Sclerosis by Dunckley, Travis, Huentelman, Matthew J, Craig, David W, Pearson, John V, Szelinger, Szabolcs, Joshipura, Keta, Halperin, Rebecca F, Stamper, Chelsea, Jensen, Kendall R, Letizia, David, Hesterlee, Sharon E, Pestronk, Alan, Levine, Todd, Bertorini, Tulio, Graves, Michael C, Mozaffar, Tahseen, Jackson, Carlayne E, Bosch, Peter, McVey, April, Dick, Arthur, Barohn, Richard, Lomen-Hoerth, Catherine, Rosenfeld, Jeffrey, O'Connor, Daniel T, Zhang, Kuixing, Crook, Richard, Ryberg, Henrik, Hutton, Michael, Katz, Jonathan, Simpson, Ericka P, Mitsumoto, Hiroshi, Bowser, Robert, Miller, Robert G, Appel, Stanley H, Stephan, Dietrich A

“…A genomewide analysis of sporadic ALS suggests that a variant of FLJ10986, a gene of unknown function expressed in the spinal cord and other tissues, may…”
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Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue by Henkel, Jenny S., Engelhardt, Joseph I., Siklós, László, Simpson, Ericka P., Kim, Seung H., Pan, Tianhong, Goodman, J. Clay, Siddique, Teepu, Beers, David R., Appel, Stanley H.

“…Dendritic cells are potent antigen‐presenting cells that initiate and amplify immune responses. To determine whether dendritic cells participate in…”
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Acute Onset of Guillain-Barré Syndrome After Elective Spinal Surgery by Boghani, Zain, Livingston, Andrew D, Simpson, Ericka P, Holman, Paul J, Grossman, Robert G

“…Background Guillain-Barré syndrome (GBS) is an acute peripheral neuropathy caused by an autoimmune response against myelin of peripheral nerves. GBS has been…”
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Neuroinflammatory mechanisms in amyotrophic lateral sclerosis pathogenesis by Thonhoff, Jason R, Simpson, Ericka P, Appel, Stanley H

“…Neuroinflammation is increasingly recognized as an important mediator of disease progression in patients with amyotrophic lateral sclerosis (ALS), and is…”
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Neurogenic Orthostatic Hypotension: a Common Complication of Successful Pancreas Transplantation by Kuten, Samantha A., Graviss, Edward A., Nguyen, Duc T., Gaber, A. Osama, Sadhu, Archana R., Simpson, Ericka P., Yi, Stephanie G., Podder, Hemangshu, Kagan, Anna, Knight, Richard J.

“…Orthostatic hypotension (OH) is a poorly understood complication of simultaneous pancreas-kidney (SPK) transplantation. We sought to determine the incidence,…”
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Activated Microglia Initiate Motor Neuron Injury by a Nitric Oxide and Glutamate-Mediated Mechanism by ZHAO, WEIHUA, XIE, WENJIE, LE, WEIDONG, BEERS, DAVID R, HE, YI, HENKEL, JENNY S, SIMPSON, ERICKA P, YEN, ALBERT A, XIAO, QIN, APPEL, STANLEY H

“…Recent studies suggest that motor neuron (MN) death may be non-cell autonomous, with cell injury mediated by interactions involving non-neuronal cells, such as…”
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Predictability of disease progression in amyotrophic lateral sclerosis by Czaplinski, Adam, Yen, Albert A., Simpson, Ericka P., Appel, Stanley H.

“…The aim of this study was to determine the predictors of disease progression in a group of 832 patients with the diagnosis of definite or probable amyotrophic…”
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Expanded autologous regulatory T-lymphocyte infusions in ALS: A phase I, first-in-human study by Thonhoff, Jason R, Beers, David R, Zhao, Weihua, Pleitez, Milvia, Simpson, Ericka P, Berry, James D, Cudkowicz, Merit E, Appel, Stanley H

“…OBJECTIVETo determine whether autologous infusions of expanded regulatory T lymphoctyes (Tregs) into patients with amyotrophic lateral sclerosis (ALS) are safe…”
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Contemporary Neuroscience Core Curriculum for Medical Schools by Gelb, Douglas J, Kraakevik, Jeff, Safdieh, Joseph E, Agarwal, Sachin, Odia, Yazmin, Govindarajan, Raghav, Quick, Adam, Soni, Madhu, Bickel, Jennifer, Gamaldo, Charlene, Hannon, Peter, Hatch, Hayden A M, Hernandez, Christian, Merlin, Lisa R, Noble, James M, Reyes-Iglesias, Yolanda, Salas, Rachel Marie E, Sandness, David James, Treat, Lauren, Benameur, Karima, Brown, Jr, Robert D, DeLuca, Gabriele C, Garg, Neeta, Goldstein, Larry B, Gutmann, Laurie, Henchcliffe, Claire, Hessler, Amy, Jordan, Justin T, Kilgore, Shannon M, Khan, Jaffar, Levin, Kerry H, Mohile, Nimish A, Nevel, Kathryn S, Roberts, Kirk, Said, Rana R, Simpson, Ericka P, Sirven, Joseph I, Smith, A Gordon, Southerland, Andrew Mebane, Wilson, Rujuta B

“…Medical students need to understand core neuroscience principles as a foundation for their required clinical experiences in neurology. In fact, they need a…”
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PARP Expression Is Increased in Astrocytes but Decreased in Motor Neurons in the Spinal Cord of Sporadic ALS Patients by KIM, SEUNG H, HENKEL, JENNY S, BEERS, DAVID R, SENGUN, IHSAN S, SIMPSON, ERICKA P, GOODMAN, J CLAY, ENGELHARDT, JOZSEF I, SIKLÓS, LÁSZLÓ, APPEL, STANLEY H

“…The evidence for increased oxidative stress and DNA damage in amyotrophic lateral sclerosis (ALS) prompted studies to determine if the expression of…”
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Oxidative Stress: a common denominator in the pathogenesis of amyotrophic lateral sclerosis by Simpson, Ericka P, Yen, Albert A, Appel, Stanley H

“…PURPOSE OF REVIEWAmyotrophic lateral sclerosis, or Lou Gehrig disease, is a progressive neurodegenerative disease of adult onset characterized by a loss of…”
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Antioxidant treatment for amyotrophic lateral sclerosis by Simpson, Ericka P

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“Individual and health-related quality of life assessment in amyotrophic lateral sclerosis patients and their caregivers” by Lo Coco G, Lo Coco D, Cicero V, Oliveri A, Lo Verso G, Piccolo F, La Bella V by Simpson, Ericka P., Appel, Stanley H.

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Ethical Considerations in Dementia Diagnosis and Care: AAN Position Statement by Chiong, Winston, Tsou, Amy Y., Simmons, Zachary, Bonnie, Richard J., Russell, James A.

“…Alzheimer disease and other dementias present unique practical challenges for patients, their families, clinicians, and health systems. These challenges…”
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Activated microglia: the silent executioner in neurodegenerative disease? by Appel, S H, Simpson, E P

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Mechanisms of disease pathogenesis in amyotrophic lateral sclerosis. A central role for calcium by Simpson, Ericka P, Mosier, Dennis, Appel, Stanley H

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Slower disease progression and prolonged survival in contemporary patients with amyotrophic lateral sclerosis: is the natural history of amyotrophic lateral sclerosis changing? by Czaplinski, Adam, Yen, Albert A, Simpson, Ericka P, Appel, Stanley H

“…In recent years, considerable effort has been made to improve the treatment of patients with amyotrophic lateral sclerosis (ALS). However, despite the…”
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Randomized phase 2 trial of NP001–a novel immune regulator: Safety and early efficacy in ALS by Miller, Robert G, Block, Gilbert, Barohn, Richard J, Cudkowicz, Merit, Zhang, Jane R, McGrath, Michael S, Appel, Stan H, Katz, Jonathan, Kushner, Giovanna, Wong, Cynthia, Akers, Amy, Zayas-Bazan, Thais, McCoy, Shelly, Goyal, Neelam, Harris, Will, Gonella, Marie, Brooks, Benjamin R, Bravver, Elena, Sanjak, Mohammed, Ward, Amber L, Mehrizi, Amir, Belfiore, Mark, Lary, Cynthia, Nemeth, Joanne, Conway, Jill, Holsten, Scott, Shue, Jamie, Mitsumoto, Hiroshi, Youngman, Regina, Lee, Yei-won, Dalton, Kate, Bedlack, Richard S, Morgenlander, Joel Charles, Boyette, Candace Lee, Grace, Karen L, Thomas Hickey, Patrick, Perry-Trice, Peggy, Berry, James, Atassi, Nazem, Boylan, Kevin, Kennelly, Kathleen, DeSaro, Pamela, Johnston, Amelia, Huser, Angela, Fuqua, Paula, Staggs, Kristin, Babcock, Lorraine, Kryston, Thomas, Bosch, E Peter, Verheijde, Josephus L, Grover, Yvvonne, Lee, Michael S, Musil, Danette J, Whiteman, Dana, Simpson, Ericka P, Pleitez, Milvia Y, Lay, Luis F, Schwartz, Thomas, Blanton, Linda, Lai, Eugene C, Berry, Nicole, Khan, Sara, Chowdhury, Nabi, Goslin, Kimberly, Carter, Gregory T, Ann Kovarik, Mary, Simionescu, Laura, Reale, Melissa A, Markis, Katie, Money, Kristina, Boevin, Travis, Lava, Neil, Glass, Jonathan D, Polak, Meraida, Shaw, Latoya, Bordeau, Jane, Rogers, Susan, Ferguson, Susan, Kelly, Crystal, Mozaffar, Tahseen, Ramsey, Gladys, Tully, Patricia A, Alvarez, Rebecca, Barohn, Richard, Dimachkie, Mazen M, Pasnoor, Mamatha, Herbelin, Laura, Kasarskis, Edward J, Dotson, William F, Sitzlar, Stephen C, Tandy, Tammy, Carrico, Jeffery, Rice, Linda, Chamblin, Lisa, Townsend, Janet, Hanley-Borgia, Lisa, Vanderpool, Kathryn E, Taylor, Deborah G, Hutchinson, Jan, King, Jason T

“…OBJECTIVE:To assess the safety, tolerability, and preliminary efficacy of NP001, a novel immune regulator of inflammatory monocytes/macrophages, for slowing…”
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Hypercaloric enteral nutrition in Amyotrophic Lateral Sclerosis: a randomized double-blind placebo-controlled trial by Wills, Anne-Marie, Hubbard, Jane, Macklin, Eric A., Glass, Jonathan, Tandan, Rup, Simpson, Ericka P, Brooks, Benjamin, Gelinas, Deborah, Mitsumoto, Hiroshi, Mozaffar, Tahseen, Hanes, Gregory P., Ladha, Shafeeq S., Heiman-Patterson, Terry, Katz, Jonathan, Lou, Jau-Shin, Mahoney, Katy, Grasso, Daniela, Lawson, Robert, Yu, Hong, Cudkowicz, Merit

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