Search Results - "Simpson, Craig A."

The impact of acute and chronic exercise on Nrf2 expression in relation to markers of mitochondrial biogenesis in human skeletal muscle by Islam, Hashim, Bonafiglia, Jacob T., Turnbull, Patrick C., Simpson, Craig A., Perry, Christopher G. R., Gurd, Brendon J.

“…Purpose To examine the relationship between changes in nuclear factor erythroid 2-related factor 2 (Nrf2) expression and markers of mitochondrial biogenesis in…”
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Reducing the intensity and volume of interval training diminishes cardiovascular adaptation but not mitochondrial biogenesis in overweight/obese men by Boyd, J Colin, Simpson, Craig A, Jung, Mary E, Gurd, Brendon J

“…The purpose of this research was to determine if the adaptations to high intensity interval training (HIT) are mitigated when both intensity and training…”
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Dissociation of increases in PGC-1α and its regulators from exercise intensity and muscle activation following acute exercise by Edgett, Brittany A, Foster, William S, Hankinson, Paul B, Simpson, Craig A, Little, Jonathan P, Graham, Ryan B, Gurd, Brendon J

“…Muscle activation as well as changes in peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) following high-intensity interval…”
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Contribution of central and peripheral adaptations to changes in maximal oxygen uptake following 4 weeks of sprint interval training by Raleigh, James P, Giles, Matthew D, Islam, Hashim, Nelms, Matthew, Bentley, Robert F, Jones, Joshua H, Neder, J Alberto, Boonstra, Kristen, Quadrilatero, Joe, Simpson, Craig A, Tschakovsky, Michael E, Gurd, Brendon J

“…The current study examined the contribution of central and peripheral adaptations to changes in maximal oxygen uptake (V̇O ) following sprint interval training…”
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Intramuscular hematoma of the vastus lateralis following percutaneous skeletal muscle microbiopsy: a case report by Drouin, Patrick J., Islam, Hashim, Simpson, Craig A., Gurd, Brendon J.

“…Recently, percutaneous microbiopsy needles have been used as a less invasive alternative to the Bergstrom needle for obtaining human skeletal muscle biopsy to…”
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An examination of resveratrol's mechanisms of action in human tissue: impact of a single dose in vivo and dose responses in skeletal muscle ex vivo by Williams, Cameron B, Hughes, Meghan C, Edgett, Brittany A, Scribbans, Trisha D, Simpson, Craig A, Perry, Christopher G R, Gurd, Brendon J

“…The current study tested the hypothesis that a single, moderate dose of RSV would activate the AMPK/SIRT1 axis in human skeletal muscle and adipose tissue…”
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Nutritional intervention to enhance recovery after arthroscopic knee surgery in adults: a randomized controlled pilot trial by Nyman, Danielle L. E., Pufahl, Callum J., Hickey, Olivia G. V., Stokes, Tanner, Simpson, Craig A., Selinger, Jessica C., Mathur, Sunita, Janssen, Ian, Giangregorio, Lora M., Bardana, Davide D., McGlory, Chris

“…Background Essential amino acid (EAA) and omega-3 fatty acid ingestion independently attenuate leg skeletal muscle disuse atrophy in uninjured persons…”
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A comparison of pain responses, hemodynamic reactivity and fibre type composition between Bergström and microbiopsy skeletal muscle biopsies by Bonafiglia, Jacob T., Islam, Hashim, Preobrazenski, Nicholas, Drouin, Patrick, Ma, Andrew, Gerhart, Austin, Quadrilatero, Joe, Tschakovsky, Michael E., Tripp, Dean A., Perry, Christopher G.R., Simpson, Craig A., Gurd, Brendon J.

“…This study tested the hypotheses that 1) skeletal muscle biopsies performed with the Bergström needle evoke larger perceptions of pain and greater hemodynamic…”
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Increasing whole-body energetic stress does not augment fasting-induced changes in human skeletal muscle by Islam, Hashim, Amato, Alessandra, Bonafiglia, Jacob T., Rahman, Fasih A., Preobrazenski, Nicholas, Ma, Andrew, Simpson, Craig A., Quadrilatero, Joe, Gurd, Brendon J.

“…Fasting rapidly (≤ 6 h) activates mitochondrial biogenic pathways in rodent muscle, an effect that is absent in human muscle following prolonged (10–72 h)…”
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Repeatability of exercise‐induced changes in mRNA expression and technical considerations for qPCR analysis in human skeletal muscle by Islam, Hashim, Edgett, Brittany A., Bonafiglia, Jacob T., Shulman, Talya, Ma, Andrew, Quadrilatero, Joe, Simpson, Craig A., Gurd, Brendon J.

“…New Findings What is the central question of this study? Are individual changes in exercise‐induced mRNA expression repeatable (i.e. representative of the true…”
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Repeatability of training-induced skeletal muscle adaptations in active young males by Islam, Hashim, Bonafiglia, Jacob T., Del Giudice, Michael, Pathmarajan, Rishiga, Simpson, Craig A., Quadrilatero, Joe, Gurd, Brendon J.

“…Measurements of protein content, enzymatic activity, and/or capillarization are frequently utilized as markers of skeletal muscle adaptation following exercise…”
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Fiber-specific and whole-muscle LRP130 expression in rested, exercised, and fasted human skeletal muscle by Islam, Hashim, Ma, Andrew, Amato, Alessandra, Cuillerier, Alexanne, Burelle, Yan, Simpson, Craig A., Quadrilatero, Joe, Gurd, Brendon J.

“…Leucine-rich pentatricopeptide repeat motif-containing protein (LRP130) is implicated in the control of mitochondrial gene expression and oxidative…”
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Resveratrol supplementation does not augment performance adaptations or fibre-type-specific responses to high-intensity interval training in humans by Scribbans, Trisha D, Ma, Jasmin K, Edgett, Brittany A, Vorobej, Kira A, Mitchell, Andrew S, Zelt, Jason G E, Simpson, Craig A, Quadrilatero, Joe, Gurd, Brendon J

“…The present study examined the effect of concurrent exercise training and daily resveratrol (RSV) supplementation (150 mg) on training-induced adaptations…”
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Acute upregulation of PGC-1α mRNA correlates with training-induced increases in SDH activity in human skeletal muscle by Bonafiglia, Jacob T, Edgett, Brittany A, Baechler, Brittany L, Nelms, Matthew W, Simpson, Craig A, Quadrilatero, Joe, Gurd, Brendon J

“…The purpose of the present study was to determine if acute responses in PGC-1α, VEGFA, SDHA, and GPD1-2 mRNA expression predict their associated chronic…”
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SIRT3 gene expression but not SIRT3 subcellular localization is altered in response to fasting and exercise in human skeletal muscle by Edgett, Brittany A., Hughes, Meghan C., Matusiak, Jennifer B. L., Perry, Christopher G. R., Simpson, Craig A., Gurd, Brendon J.

“…New Findings What is the central question of this study? Evidence from cellular and animal models suggests that SIRT3 is involved in regulating aerobic ATP…”
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The impact of a 48-h fast on SIRT1 and GCN5 in human skeletal muscle by Edgett, Brittany A, Scribbans, Trisha D, Raleigh, James P, Matusiak, Jennifer B L, Boonstra, Kristen, Simpson, Craig A, Perry, Christopher G R, Quadrilatero, Joe, Gurd, Brendon J

“…The present study examined the impact of a 48 h fast on the expression and activation status of SIRT1 and GCN5, the relationship between SIRT1/GCN5 and the…”
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Effect of Acute High-intensity Interval Exercise on Whole-body Fat Oxidation and Subcutaneous Adipose Tissue Cell Signaling in Overweight Women by Islam, Hashim, Smith, Marysa M W, Scribbans, Trisha D, McCrady, Emma, Castellani, Laura N, Allen, Matti D, Wright, David C, Simpson, Craig A, Gurd, Brendon J

“…Exercise-induced alterations in adipose tissue insulin and/or β-adrenergic signaling may contribute to increases in whole-body fat oxidation following acute…”
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Improvements in aerobic fitness but not mitochondrial content are intensity dependent in overweight men by Boyd, John Colin, Simpson, Craig A, Jung, Mary E, Gurd, Brendon J

“…Abstract only The objective of this research was to determine the impact of the intensity of interval training on aerobic fitness, exercise performance, and…”
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The impact of a single dose of resveratrol on intramuscular signaling and whole body fat oxidation in humans by Williams, Cameron Bryce, Zelt, Jason G E, Simpson, Craig A, Gurd, Brendon J

“…Abstract only Resveratrol's (RSV) mechanism of action in skeletal muscle has been characterized in cellular and murine models, but RSV's in vivo signaling…”
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A comparison of fiber specific and whole muscle homogenate markers of muscle activation following HIT and END exercise by Scribbans, Trisha D, Mitchell, Andrew S, Vorobej, Kira, Simpson, Craig A, Quadrilatero, Joe, Gurd, Brendon J

“…Abstract only Muscle activation following a bout of high‐intensity interval training (HIT) and endurance exercise (END) was examined in recreationally active…”
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