Search Results - "Simoulis, Athanasios"

Assessing the accuracy of [18F]PSMA-1007 PET/CT for primary staging of lymph node metastases in intermediate- and high-risk prostate cancer patients by Ingvar, Jacob, Hvittfeldt, Erland, Trägårdh, Elin, Simoulis, Athanasios, Bjartell, Anders

“…Background [ 18 F]PSMA-1007 is a promising tracer for integrated positron emission tomography and computed tomography (PET/CT). Objective Our aim was to assess…”
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Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration‐resistant prostate cancer by Semenas, Julius, Wang, Tianyan, Sajid Syed Khaja, Azharuddin, Firoj Mahmud, AKM, Simoulis, Athanasios, Grundström, Thomas, Fällman, Maria, Persson, Jenny L.

“…In the present study, we unrevealed the effect of tamoxifen on ERα and PIP5K1α/AKT that are responsible for prostate cancer growth and invasion. Tamoxifen in…”
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Development and validation of a 25-Gene Panel urine test for prostate cancer diagnosis and potential treatment follow-up by Johnson, Heather, Guo, Jinan, Zhang, Xuhui, Zhang, Heqiu, Simoulis, Athanasios, Wu, Alan H B, Xia, Taolin, Li, Fei, Tan, Wanlong, Johnson, Allan, Dizeyi, Nishtman, Abrahamsson, Per-Anders, Kenner, Lukas, Feng, Xiaoyan, Zou, Chang, Xiao, Kefeng, Persson, Jenny L, Chen, Lingwu

“…Heterogeneity of prostate cancer (PCa) contributes to inaccurate cancer screening and diagnosis, unnecessary biopsies, and overtreatment. We intended to…”
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FDG-PET/CT for lymph node staging prior to radical cystectomy by Pihl, Vilhelm, Markus, Maria, Abrahamsson, Johan, Bläckberg, Mats, Hagberg, Oskar, Kollberg, Petter, Simoulis, Athanasios, Trägårdh, Elin, Liedberg, Fredrik

“…Background 18 F-Fluorodeoxyglucose positron emission combined with computed tomography (FDG-PET/CT) has been proposed to improve preoperative staging in…”
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FcγRIIIa receptor interacts with androgen receptor and PIP5K1α to promote growth and metastasis of prostate cancer by Larsson, Per Flodbring, Karlsson, Richard, Sarwar, Martuza, Miftakhova, Regina, Wang, Tianyan, Syed Khaja, Azharuddin Sajid, Semenas, Julius, Chen, Sa, Hedblom, Andreas, Ali, Amjad, Ekström‐Holka, Kristina, Simoulis, Athanasios, Kumar, Anjani, Wingren, Anette Gjörloff, Robinson, Brian, Nyunt Wai, Sun, Mongan, Nigel P., Heery, David M., Öhlund, Daniel, Grundström, Thomas, Ødum, Niels, Persson, Jenny L.

“…Low‐affinity immunoglobulin gamma Fc region receptor III‐A (FcγRIIIa) is a cell surface protein that belongs to a family of Fc receptors that facilitate the…”
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Urodrill - a novel MRI-guided endoscopic biopsy technique to sample and molecularly classify muscle-invasive bladder cancer without fractionating the specimen during transurethral resection by Eriksson, Pontus, Berg, Johanna, Bernardo, Carina, Bobjer, Johannes, Brändstedt, Johan, Löfgren, Annica, Simoulis, Athanasios, Sjödahl, Gottfrid, Sundén, Fredrik, Wokander, Mats, Zackrisson, Sophia, Liedberg, Fredrik

“…The current diagnostic pathway for patients with muscle-invasive bladder cancer (MIBC), which involves with computed tomography urography, cystoscopy, and…”
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A 23‐Gene Classifier urine test for prostate cancer prognosis by Guo, Jinan, Johnson, Heather, Zhang, Xuhui, Feng, Xiaoyan, Zhang, Heqiu, Simoulis, Athanasios, Wu, Alan HB, Xia, Taolin, Li, Fei, Tan, Wanlong, Johnson, Allan, Dizeyi, Nishtman, Abrahamsson, Per‐Anders, Kenner, Lukas, Chen, Lingwu, Zhong, Wanmei, Xiao, Kefeng, Persson, Jenny L., Zou, Chang

“…The patients were divided into two risk groups based on diagnosis by the 23-Gene Classifier and Kaplan-Meier survival analysis showed statistically significant…”
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Non-invasive Urine Test for Molecular Classification of Clinical Significance in Newly Diagnosed Prostate Cancer Patients by Guo, Jinan, Zhang, Xuhui, Xia, Taolin, Johnson, Heather, Feng, Xiaoyan, Simoulis, Athanasios, Wu, Alan H. B., Li, Fei, Tan, Wanlong, Johnson, Allan, Dizeyi, Nishtman, Abrahamsson, Per-Anders, Kenner, Lukas, Xiao, Kefeng, Zhang, Heqiu, Chen, Lingwu, Zou, Chang, Persson, Jenny L.

“…Objective: To avoid over-treatment of low-risk prostate cancer patients, it is important to identify clinically significant and insignificant cancer for…”
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Tumor Detection of 18F-PSMA-1007 in the Prostate Gland in Patients with Prostate Cancer Using Prostatectomy Specimens as Reference Method by Trägårdh, Elin, Simoulis, Athanasios, Bjartell, Anders, Jögi, Jonas

“…Prostate-specific membrane antigen (PSMA) radiopharmaceuticals used with PET/CT are a promising tool for managing patients with prostate cancer. This study…”
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Tumor detection of 18 F-PSMA-1007 in the prostate gland in patients with prostate cancer using prostatectomy specimens as reference method by Tragardh, Elin, Simoulis, Athanasios, Bjartell, Anders, Jogi, Jonas

“…Prostate-specific membrane antigen (PSMA) radiopharmaceuticals used with positron emission tomography/computed tomography (PET-CT) are a promising tool for…”
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Artificial intelligence for detection of prostate cancer in biopsies during active surveillance by Arvidsson, Ida, Svanemur, Edvard, Marginean, Felicia, Simoulis, Athanasios, Overgaard, Niels Christian, Åström, Kalle, Heyden, Anders, Krzyzanowska, Agnieszka, Bjartell, Anders

“…Objectives To evaluate a cancer detecting artificial intelligence (AI) algorithm on serial biopsies in patients with prostate cancer on active surveillance…”
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Sanctuary Testicular Bladder Cancer Metastasis 10 Years After Radical Cystectomy and Adjuvant Chemotherapy by Saemundsson, Ymir, Simoulis, Athanasios, Liedberg, Fredrik

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Complete metabolic response with [18F]fluorodeoxyglucose‐positron emission tomography/computed tomography predicts survival following induction chemotherapy and radical cystectomy in clinically lymph node positive bladder cancer by Abrahamsson, Johan, Kollberg, Petter, Almquist, Helen, Bläckberg, Mats, Brändstedt, Johan, Lyttkens, Kerstin, Simoulis, Athanasios, Sjödahl, Gottfrid, Sörenby, Anne, Trägårdh, Elin, Liedberg, Fredrik

“…Objective To determine whether repeated [18F]fluorodeoxyglucose‐positron emission tomography/computed tomography (FDG‐PET‐CT) scans can predict increased…”
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The functional interlink between AR and MMP9/VEGF signaling axis is mediated through PIP5K1α/pAKT in prostate cancer by Larsson, Per, Syed Khaja, Azharuddin Sajid, Semenas, Julius, Wang, Tianyan, Sarwar, Martuza, Dizeyi, Nishtman, Simoulis, Athanasios, Hedblom, Andreas, Wai, Sun Nyunt, Ødum, Niels, Persson, Jenny L.

“…Currently, no effective targeted therapeutics exists for treatment of metastatic prostate cancer (PCa). Given that matrix metalloproteinases 9 (MMP9) and its…”
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Cyclin A1 and P450 Aromatase Promote Metastatic Homing and Growth of Stem-like Prostate Cancer Cells in the Bone Marrow by Miftakhova, Regina, Hedblom, Andreas, Semenas, Julius, Robinson, Brian, Simoulis, Athanasios, Malm, Johan, Rizvanov, Albert, Heery, David M, Mongan, Nigel P, Maitland, Norman J, Allegrucci, Cinzia, Persson, Jenny L

“…Bone metastasis is a leading cause of morbidity and mortality in prostate cancer. While cancer stem-like cells have been implicated as a cell of origin for…”
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K-RAS Associated Gene-Mutation-Based Algorithm for Prediction of Treatment Response of Patients with Subtypes of Breast Cancer and Especially Triple-Negative Cancer by Johnson, Heather, Ali, Amjad, Zhang, Xuhui, Wang, Tianyan, Simoulis, Athanasios, Wingren, Anette Gjörloff, Persson, Jenny L

“…Purpose: There is an urgent need for developing new biomarker tools to accurately predict treatment response of breast cancer, especially the deadly…”
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Gene-Mutation-Based Algorithm for Prediction of Treatment Response in Colorectal Cancer Patients by Johnson, Heather, El-Schich, Zahra, Ali, Amjad, Zhang, Xuhui, Simoulis, Athanasios, Wingren, Anette Gjörloff, Persson, Jenny L

“…Purpose: Despite the high mortality of metastatic colorectal cancer (mCRC), no new biomarker tools are available for predicting treatment response. We…”
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An Artificial Intelligence–based Support Tool for Automation and Standardisation of Gleason Grading in Prostate Biopsies by Marginean, Felicia, Arvidsson, Ida, Simoulis, Athanasios, Christian Overgaard, Niels, Åström, Kalle, Heyden, Anders, Bjartell, Anders, Krzyzanowska, Agnieszka

“…Gleason grading is the standard diagnostic method for prostate cancer and is essential for determining prognosis and treatment. The dearth of expert…”
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Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells by Sarwar, Martuza, Semenas, Julius, Miftakhova, Regina, Simoulis, Athanasios, Robinson, Brian, Gjörloff Wingren, Anette, Mongan, Nigel P, Heery, David M, Johnsson, Heather, Abrahamsson, Per-Anders, Dizeyi, Nishtman, Luo, Jun, Persson, Jenny L

“…One mechanism of resistance of prostate cancer (PCa) to enzalutamide (MDV3100) treatment is the increased expression of AR variants lacking the ligand…”
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Establishment of Prostate Tumor Growth and Metastasis Is Supported by Bone Marrow Cells and Is Mediated by PIP5K1[alpha] Lipid Kinase by Karlsson, Richard, Larsson, Per, Miftakhova, Regina, Khaja, Azharuddin Sajid Syed, Sarwar, Martuza, Semenas, Julius, Chen, Sa, Hedblom, Andreas, Wang, Tianyan, Ekstrom-Holka, Kristina, Simoulis, Athanasios, Kumar, Anjani, Odum, Niels, Grundstrom, Thomas, Persson, Jenny L

“…Simple Summary: Metastatic castration-resistant PCa (mCRPC) is a clinically highly lethal disease; the mechanisms underlying the lethal disease remain poorly…”
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