Search Results - "Simony, Joelle"

SPARC in cancer‐associated fibroblasts is an independent poor prognostic factor in non‐metastatic triple‐negative breast cancer and exhibits pro‐tumor activity by Alcaraz, Lindsay B., Mallavialle, Aude, Mollevi, Caroline, Boissière‐Michot, Florence, Mansouri, Hanane, Simony‐Lafontaine, Joelle, Laurent‐Matha, Valérie, Chardès, Thierry, Jacot, William, Turtoi, Andrei, Roger, Pascal, Guiu, Séverine, Liaudet‐Coopman, Emmanuelle

“…Triple‐negative breast cancer (TNBC) is the most aggressive breast cancer subtype and lacks specific targeted therapeutic agents. The current mechanistic…”
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Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump by Mazard, Thibault, Causse, Annick, Simony, Joelle, Leconet, Wilhem, Vezzio-Vie, Nadia, Torro, Adeline, Jarlier, Marta, Evrard, Alexandre, Del Rio, Maguy, Assenat, Eric, Martineau, Pierre, Ychou, Marc, Robert, Bruno, Gongora, Celine

“…Despite recent advances in the treatment of colorectal cancer (CRC), tumor resistance is a frequent cause of chemotherapy failure. Therefore, new treatment…”
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Estrogen Receptor β (ERβ) Level but Not Its ERβcx Variant Helps to Predict Tamoxifen Resistance in Breast Cancer by ESSLIMANI-SAHLA, Majida, SIMONY-LAFONTAINE, Joelle, KRAMAR, Andrew, LAVAILL, Roselyne, MOLLEVI, Caroline, WARNER, Margaret, GUSTAFSSON, Jan-Ake, ROCHEFORT, Henri

“…The antiestrogen tamoxifen, a major endocrine therapy of estrogen receptor (ER)-positive breast cancer, is nevertheless inefficient in 30 to 40% of cases for…”
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Immunohistochemical Assessment of the Peripheral Benzodiazepine Receptor in Breast Cancer and Its Relationship with Survival by GALIEGUE, Sylvaine, CASELLAS, Pierre, KRAMAR, Andrew, TINEL, Norbert, SIMONY-LAFONTAINE, Joelle

“…Purpose: The peripheral benzodiazepine receptor (PBR) expression has been shown dramatically increased in neoplastic tissues and tumor cell lines originated…”
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Quantification of HER1, HER2 and HER3 by time-resolved Förster resonance energy transfer in FFPE triple-negative breast cancer samples by Ho-Pun-Cheung, Alexandre, Bazin, Hervé, Boissière-Michot, Florence, Mollevi, Caroline, Simony-Lafontaine, Joëlle, Landas, Emeline, Bleuse, Jean-Pierre, Chardès, Thierry, Prost, Jean-François, Pèlegrin, André, Jacot, William, Mathis, Gérard, Lopez-Crapez, Evelyne

“…Background Triple-negative breast cancer (TNBC) has a worse prognosis compared with other breast cancer subtypes, and biomarkers to identify patients at high…”
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Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies by Ashraf, Yahya, Mansouri, Hanane, Laurent-Matha, Valérie, Alcaraz, Lindsay B, Roger, Pascal, Guiu, Séverine, Derocq, Danielle, Robin, Gautier, Michaud, Henri-Alexandre, Delpech, Helène, Jarlier, Marta, Pugnière, Martine, Robert, Bruno, Puel, Anthony, Martin, Lucie, Landomiel, Flavie, Bourquard, Thomas, Achour, Oussama, Fruitier-Arnaudin, Ingrid, Pichard, Alexandre, Deshayes, Emmanuel, Turtoi, Andrei, Poupon, Anne, Simony-Lafontaine, Joëlle, Boissière-Michot, Florence, Pirot, Nelly, Bernex, Florence, Jacot, William, du Manoir, Stanislas, Theillet, Charles, Pouget, Jean-Pierre, Navarro-Teulon, Isabelle, Bonnefoy, Nathalie, Pèlegrin, André, Chardès, Thierry, Martineau, Pierre, Liaudet-Coopman, Emmanuelle

“…Triple-negative breast cancer (TNBC) treatment is currently restricted to chemotherapy. Hence, tumor-specific molecular targets and/or alternative therapeutic…”
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A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment by Alcaraz, Lindsay B, Mallavialle, Aude, David, Timothée, Derocq, Danielle, Delolme, Frédéric, Dieryckx, Cindy, Mollevi, Caroline, Boissière-Michot, Florence, Simony-Lafontaine, Joëlle, Du Manoir, Stanislas, Huesgen, Pitter F, Overall, Christopher M, Tartare-Deckert, Sophie, Jacot, William, Chardès, Thierry, Guiu, Séverine, Roger, Pascal, Reinheckel, Thomas, Moali, Catherine, Liaudet-Coopman, Emmanuelle

“…Alternative therapeutic strategies based on tumor-specific molecular targets are urgently needed for triple-negative breast cancer (TNBC). The protease…”
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Increased Estrogen Receptor βcx Expression during Mammary Carcinogenesis by ESSLIMANI-SAHLA, Majida, KRAMAR, Andrew, SIMONY-LAFONTAINE, Joelle, WARNER, Margaret, GUSTAFSSON, Jan-Ake, ROCHEFORT, Henri

“…Identification of proteins that markedly vary during early steps of mammary carcinogenesis may help to understand its pathophysiology and to develop a…”
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Neoadjuvant Percutaneous 4-Hydroxytamoxifen Decreases Breast Tumoral Cell Proliferation: A Prospective Controlled Randomized Study Comparing Three Doses of 4-Hydroxytamoxifen Gel to Oral Tamoxifen by ROUANET, Philippe, LINARES-CRUZ, Gustavo, MAUDELONDE, Thierry, DRAVET, Francois, PONJOL, Sylvain, GOURGOU, Sophie, SIMONY-LAFONTAINE, Joelle, GRENIER, Jean, KRAMAR, Andrew, GIRAULT, Jean, LE NESTOUR, Elisabeth

“…Two chemoprevention randomized studies using tamoxifen showed drug efficacy; however, adverse effects such as hot flushes, endometrial cancer, and above all,…”
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Increased expression of fatty acid synthase and progesterone receptor in early steps of human mammary carcinogenesis by Esslimani‐Sahla, Majida, Thezenas, Simon, Simony‐Lafontaine, Joelle, Kramar, Andrew, Lavaill, Roselyne, Chalbos, Dany, Rochefort, Henri

“…Progestins increase the risk of breast cancer in the hormone therapy of menopause, and progesterone receptor‐induced fatty acid synthase (FAS) is a potential…”
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Prognostic value of androgen receptor and FOXA1 co-expression in non-metastatic triple negative breast cancer and correlation with other biomarkers by Guiu, Séverine, Mollevi, Caroline, Charon-Barra, Céline, Boissière, Florence, Crapez, Evelyne, Chartron, Elodie, Lamy, Pierre-Jean, Gutowski, Marian, Bourgier, Céline, Romieu, Gilles, Simony-Lafontaine, Joelle, Jacot, William

“…Background In luminal androgen receptor (AR) tumours, FOXA1 may direct AR to sites occupied by ER in luminal tumours, thus stimulating proliferation. Methods…”
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High Histone Deacetylase 7 (HDAC7) Expression Is Significantly Associated with Adenocarcinomas of the Pancreas by Ouaïssi, Mehdi, Sielezneff, Igor, Silvestre, Ricardo, Sastre, Bernard, Bernard, Jean-Paul, Lafontaine, Joelle Simony, Payan, Marie José, Dahan, Laetitia, Pirrò, Nicolas, Seitz, Jean François, Mas, Eric, Lombardo, Dominique, Ouaissi, Ali

“…Background Alterations in HDAC s gene expression have been reported in a number of human cancers. No information is available concerning the status of HDAC s…”
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Risk Factors for Recurrence and Metastasis After Breast-Conserving Therapy for Ductal Carcinoma-In-Situ: Analysis of European Organization for Research and Treatment of Cancer Trial 10853 by BIJKER, Nina, PETERSE, Johannes L, DUCHATEAU, Luc, JULIEN, Jean-Pierre, FENTIMAN, Lan S, DUVAL, Christian, DI PALMA, Silvana, SIMONY-LAFONTAINE, Joëlle, DE MASCAREL, Isabelle, VAN DE VIJVER, Marc J

“…In view of the increasing number of patients treated with breast-conserving treatment (BCT) for ductal carcinoma-in-situ (DCIS), risk factors for recurrence…”
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Immunohistochemical Assessment of the Peripheral Benzodiazepine Receptor in Human Tissues by Bribes, Estelle, Carrière, Dominique, Goubet, Catherine, Galiègue, Sylvaine, Casellas, Pierre, Joêlle, Simony-Lafontaine

“…Exhaustive analysis of the location of the peripheral benzodiazepine receptor (PBR) both at the subcellular and the tissue level is warranted to gain a better…”
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PKCθ-induced phosphorylations control the ability of Fra-1 to stimulate gene expression and cancer cell migration by Belguise, Karine, Cherradi, Sara, Sarr, Awa, Boissière, Florence, Boulle, Nathalie, Simony-Lafontaine, Joëlle, Choesmel-Cadamuro, Valérie, Wang, Xiaobo, Chalbos, Dany

“…Abstract The AP-1 transcription factor Fra-1 is aberrantly expressed in a large number of cancers and plays crucial roles in cancer development and progression…”
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Spontaneous Apoptosis in the Intra-Ductal Component's Stroma of Breast Invasive Carcinoma by ROULEAU-DUBOIS, Caroline, CUNY, Marguerite, FERRIERES, Gaelle, SIMONY-LAFONTAINE, Joelle, ROUANET, Philippe, GRENIER, Jean, JEANTEUR, Philippe, BALDET, Pierre, ESCOT, Chantal

“…Spontaneous apoptosis by in situ detection of DNA fragmentation (DNAf) was investigated in breast invasive ductal carcinoma (IDC) frozen samples removed from…”
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Oxidant‐antioxidant status in relation to survival among breast cancer patients by Saintot, Monique, Mathieu‐Daude, Hélène, Astre, Cécile, Grenier, Jean, Simony‐Lafontaine, Joelle, Gerber, Mariette

“…The role of plasma oxidant‐antioxidant status in survival after breast cancer surgery was investigated in a cohort of patients (n = 363) hospitalized in…”
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Abstract 975: Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump by Mazard, Thibault, Causse, Annick, Simony, Joelle, Leconet, Wilhem, Jarlier, Marta, Ychou, Marc, Del Rio, Maguy, Martineau, Pierre, Robert, Bruno, Gongora, Céline

“…Background: Despite recent advances in the treatment of colorectal cancer, tumor resistance is a frequent cause of chemotherapy failure. Thus, new treatment…”
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Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump: Sorafenib inhibits ABCG2 and overcome irinotecan resistance by Mazard, Thibault, Causse, Annick, Simony, Joelle, Leconet, Wilhem, Vezzio-Vie, Nadia, Torro, Adeline, Jarlier, Marta, Evrard, Alexandre, del Rio, Maguy, Assenat, Eric, Martineau, Pierre, Ychou, Marc, Robert, Bruno, Gongora, Celine

“…Despite recent advances in the treatment of colorectal cancer (CRC), tumor resistance is a frequent cause of chemotherapy failure. Therefore, new treatment…”
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PTPN13 induces cell junction stabilization and inhibits mammary tumor invasiveness by Hamyeh, Mohamed, Bernex, Florence, Larive, Romain M, Naldi, Aurélien, Urbach, Serge, Simony-Lafontaine, Joelle, Puech, Carole, Bakhache, William, Solassol, Jérome, Coopman, Peter J, Hendriks, Wiljan J A J, Freiss, Gilles

“…Clinical data suggest that the protein tyrosine phosphatase PTPN13 exerts an anti-oncogenic effect. Its exact role in tumorigenesis remains, however, unclear…”
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