Search Results - "Simonsen, U."

New roles of factors from perivascular tissue in regulation of vascular tone by Simonsen, U., Boedtkjer, E.

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Emerging roles of calcium‐activated K channels and TRPV4 channels in lung oedema and pulmonary circulatory collapse by Simonsen, U., Wandall‐Frostholm, C., Oliván‐Viguera, A., Köhler, R.

“…It has been suggested that the transient receptor potential cation (TRP) channel subfamily V (vanilloid) type 4 (TRPV4) and intermediate conductance…”
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KV7 channels are involved in hypoxia‐induced vasodilatation of porcine coronary arteries by Hedegaard, E R, Nielsen, B D, Kun, A, Hughes, A D, Krøigaard, C, Mogensen, S, Matchkov, V V, Fröbert, O, Simonsen, U

“…Background and Purpose Hypoxia causes vasodilatation of coronary arteries, but the underlying mechanisms are poorly understood. We hypothesized that hypoxia…”
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NS309 restores EDHF‐type relaxation in mesenteric small arteries from type 2 diabetic ZDF rats by Brøndum, E, Kold‐Petersen, H, Simonsen, U, Aalkjaer, C

“…Background and purpose:  The endothelium‐derived hyperpolarizing factor (EDHF)‐type relaxation in mesenteric small arteries from 21 week old Zucker lean (ZL)…”
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Openers of small conductance calcium‐activated potassium channels selectively enhance NO‐mediated bradykinin vasodilatation in porcine retinal arterioles by Dalsgaard, T, Kroigaard, C, Misfeldt, M, Bek, T, Simonsen, U

“…Background and purpose:  Small (SKCa or KCa2) and intermediate (IKCa or KCa3.1) conductance calcium‐activated potassium channels are involved in regulation of…”
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A review of wave mechanics in the pulmonary artery with an emphasis on wave intensity analysis by Su, J., Hilberg, O., Howard, L., Simonsen, U., Hughes, A. D.

“…Mean pulmonary arterial pressure and pulmonary vascular resistance (PVR) remain the most common haemodynamic measures to evaluate the severity and prognosis of…”
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Endothelial dysfunction links erectile dysfunction to heart disease by Kirby, M, Jackson, G, Simonsen, U

“…Erectile dysfunction (ED) and coronary artery disease (CAD) overlap in risk factors, aetiology and clinical outcomes. It has become clear that ED is an…”
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Oleanolic acid induces relaxation and calcium‐independent release of endothelium‐derived nitric oxide by Rodriguez‐Rodriguez, R, Stankevicius, E, Herrera, M D, Østergaard, L, Andersen, M R, Ruiz‐Gutierrez, V, Simonsen, U

“…Background and purpose: The present study investigated the mechanisms by which oleanolic acid, a component of olive oil, increases release of nitric oxide…”
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Inhibition of KV7 Channels Protects the Rat Heart against Myocardial Ischemia and Reperfusion Injury by Hedegaard, Elise R, Johnsen, Jacob, Povlsen, Jonas A, Jespersen, Nichlas R, Shanmuganathan, Jeffrey A, Laursen, Mia R, Kristiansen, Steen B, Simonsen, Ulf, Bøtker, Hans Erik

“…The voltage-gated KV7 (KCNQ) potassium channels are activated by ischemia and involved in hypoxic vasodilatation. We investigated the effect of KV7 channel…”
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NS11021, a novel opener of large-conductance Ca(2+)-activated K(+) channels, enhances erectile responses in rats by Kun, A, Matchkov, V V, Stankevicius, E, Nardi, A, Hughes, A D, Kirkeby, H J, Demnitz, J, Simonsen, U

“…Large-conductance Ca(2+)-activated K(+) channels (BK(Ca)), located on the arterial and corporal smooth muscle, are potential targets for treatment of erectile…”
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Impaired NO-mediated vasodilatation in rat coronary arteries after asphyxial cardiac arrest by TROELSEN, T. T., GRANFELDT, A., SECHER, N., TØNNESEN, E. K., SIMONSEN, U.

“…Background Cardiovascular dysfunction after cardiac arrest is a common finding. It is unknown whether altered endothelium‐mediated vasoreactivity contributes…”
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Pulmonary apelin levels and effects in rats with hypoxic pulmonary hypertension by Andersen, C.U, Markvardsen, L.H, Hilberg, O, Simonsen, U

“…Summary Background The peptide apelin is localised in the vascular endothelium and highly expressed in pulmonary tissue. The aim of this study was to…”
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Interactions between drugs for erectile dysfunction and drugs for cardiovascular disease by SIMONSEN, U

“…The association of erectile dysfunction (ED) and cardiovascular disease is well-documented in the literature and both conditions share risk factors. Therefore,…”
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Lack of tone response in retinal arterioles secondary to electrical field stimulation by Kratholm, N., Simonsen, U., Jensen, P.S., Kringelholt, S., Bek, T.

“…Purpose The retinal vascular system is devoid of autonomic nervous supply and therefore retinal blood flow is autoregulated. However, it is unknown to what…”
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Inner microvascular function assessment through an opto-mechanical polydimethylsiloxane chip by Rodriguez-Rodriguez, R, Nyvad, J, Plaza, J.A, Simonsen, U, Llobera, A, Matchkov, V, Muñoz-Berbel, X

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Apelin and pulmonary hypertension by Andersen, Charlotte U., Hilberg, Ole, Mellemkjœr, Søren, Nielsen-Kudsk, Jens E., Simonsen, U.

“…Pulmonary arterial hypertension (PAH) is a devastating disease characterized by pulmonary vasoconstriction, pulmonary arterial remodeling, abnormal…”
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ZP120 causes relaxation by pre‐junctional inhibition of noradrenergic neurotransmission in rat mesenteric resistance arteries by Simonsen, U, Laursen, B E, Petersen, J S

“…Background and purpose: ZP120 (Ac‐RYYRWKKKKKKK‐NH2), is a new partial nociceptin/orphanin FQ (NOP) receptor agonist with sodium‐potassium sparing aquaretic…”
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Vascular dysfunction produced by hyperhomocysteinemia is more severe in the presence of low folate by Symons, J David, Rutledge, John C, Simonsen, U, Pattathu, Roshny A

“…Earlier we reported that dietary folate depletion causes hyperhomocysteinemia (HHcy) and arterial dysfunction in rats (Symons JD, Mullick AE, Ensunsa JL, Ma…”
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Hyperoxia reduces basal release of nitric oxide and contracts porcine coronary arteries by Pasgaard, T, Stankevicius, E, Jørgensen, M.M, Østergaard, L, Simonsen, U, Frøbert, O

“…The purpose of the present study was to investigate whether changes in nitric oxide (NO) concentration is involved in hyperoxia-induced vasoconstriction in…”
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Elevated pressure selectively blunts flow‐evoked vasodilatation in rat mesenteric small arteries by Christensen, F H, Hansen, T, Stankevicius, E, Buus, N H, Simonsen, U

“…Background and purpose: The present study investigated mechanisms underlying impaired endothelium‐dependent vasodilatation elicited by elevating the…”
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