Search Results - "Simons, Robert W."

Physical and functional interactions among RNase E, polynucleotide phosphorylase and the cold‐shock protein, CsdA: evidence for a ‘cold shock degradosome’ by Prud’homme‐Généreux, Annie, Beran, Rudolf K., Iost, Isabelle, Ramey, C. Shane, Mackie, George A., Simons, Robert W.

“…Summary Escherichia coli contains at least five ATP‐dependent DEAD‐box RNA helicases which may play important roles in macromolecular metabolism, especially in…”
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The Economic Consequences of Rheumatoid Arthritis: Analysis of Medical Expenditure Panel Survey 2004, 2005, and 2006 Data by Simons, W. Robert, Rosenblatt, Lisa C., Trivedi, Digisha N.

“…Objective: Determine the prevalence and costs of rheumatoid arthritis (RA) during three consecutive years: 2004,2005, and 2006. Methods: Medical Expenditure…”
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The undergraduate genomics research initiative by Kerfeld, Cheryl A, Simons, Robert W

“…Students need to embrace scientific discovery directly, make connections across an otherwise diverse curriculum, learn to manage and interpret today's vast…”
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Tropism switching in Bordetella bacteriophage defines a family of diversity-generating retroelements by Miller, Jeff F, Doulatov, Sergei, Hodes, Asher, Dai, Lixin, Mandhana, Neeraj, Liu, Minghsun, Deora, Rajendar, Simons, Robert W, Zimmerly, Steven

“…Bordetella bacteriophages generate diversity in a gene that specifies host tropism. This microevolutionary adaptation is produced by a genetic element that…”
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Bex, the Bacillus subtilis Homolog of the Essential Escherichia coli GTPase Era, Is Required for Normal Cell Division and Spore Formation by Minkovsky, Natalie, Zarimani, Arash, Chary, Vasant K, Johnstone, Brian H, Powell, Bradford S, Torrance, Pamela D, Court, Donald L, Simons, Robert W, Piggot, Patrick J

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Ribonuclease PH interacts with an acidic ribonuclease E site through a basic 80-amino acid domain by Martínez, Víctor Pérez-Medina, Dehò, Gianni, Simons, Robert W., García-Mena, Jaime

“…Abstract In this work, we characterize the domains for the in vivo interaction between ribonuclease E (RNase E) and ribonuclease PH (RNase PH). We initially…”
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Reverse Transcriptase-Mediated Tropism Switching in Bordetella Bacteriophage by Liu, Minghsun, Deora, Rajendar, Doulatov, Sergei R., Gingery, Mari, Eiserling, Frederick A., Preston, Andrew, Maskell, Duncan J., Simons, Robert W., Cotter, Peggy A., Parkhill, Julian, Miller, Jeff F.

“…Host-pathogen interactions are often driven by mechanisms that promote genetic variability. We have identified a group of temperate bacteriophages that…”
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An Economic Evaluation of Colesevelam when Added to Metformin-, Insulin-or Sulfonylurea-Based Therapies in Patients with Uncontrolled Type 2 Diabetes Mellitus by SIMONS, W. Robert, HAGAN, Michael A

“…Several early studies demonstrated that bile acid sequestrants were useful for lowering lipid levels in patients with hypercholesterolaemia and may also be…”
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A Single Mutation in the IF3 N-Terminal Domain Perturbs the Fidelity of Translation Initiation at Three Levels by Maar, Dianna, Liveris, Dionysios, Sussman, Jacqueline K., Ringquist, Steven, Moll, Isabella, Heredia, Nicholas, Kil, Angela, Bläsi, Udo, Schwartz, Ira, Simons, Robert W.

“…Bacterial translation initiation factor 3 (IF3) is involved in the fidelity of translation initiation at several levels, including start-codon discrimination,…”
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The Cost of Relapse in Schizophrenia and Schizoaffective Disorder by Fitzgerald, Paul, de Castella, Anthony, Arya, Dinesh, Simons, W. Robert, Eggleston, Andrew, Meere, Sharon, Kulkarni, Jayashari

“…Objective: The aim of this study was to quantify the costs and resource utilization associated with a relapse of schizophrenia or schizoaffective disorder…”
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Comparative Effectiveness of Dalteparin and Enoxaparin in a Hospital Setting by Carson, William, Schilling, Blane, Simons, W. Robert, Parks, Connie, Choe, Yoonhee, Faria, Claudio, Powers, Annette

“…Purpose: This study compared the effectiveness of a change from enoxaparin to dalteparin for the prophylaxis of patients at risk of venous thromboembolism…”
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Variations in compliance among hypertensive patients by drug class: implications for health care costs by Rizzo, John A., Robert Simons, W.

“…Health care decision-makers require more information on differences in compliance rates associated with alternative classes of antihypertensive drugs and the…”
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Cold‐temperature induction of Escherichia coli polynucleotide phosphorylase occurs by reversal of its autoregulation by Beran, Rudolf K., Simons, Robert W.

“…When Escherichia coli cells are shifted to low temperatures (e.g. 15°C), growth halts while the ‘cold shock response’ (CSR) genes are induced, after which…”
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Regulation of the "tetCD" genes of transposon Tn10 by Pepe, C M, Suzuki, C, Laurie, C, Simons, R W

“…In addition to the genes involved in tetracycline resistance, the loop region of the composite transposon Tn10 contains two other known genes, tetC and tetD,…”
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Antisense RNA control in bacteria, phages, and plasmids by GERHART, E, WAGNER, H, SIMONS, R. W

“…Antisense RNA control is now recognized as an efficient and specific means of regulating gene expression at the posttranscriptional level. Almost all naturally…”
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Comparative cost effectiveness of angiotensin II receptor blockers in a US managed care setting: Olmesartan medoxomil compared with losartan, valsartan, and irbesartan by SIMONS, W. Robert

“…To compare the cost effectiveness of the angiotensin II receptor blockers (ARBs) olmesartan medoxomil, losartan, valsartan and irbesartan for the treatment of…”
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Cost-effectiveness of anastrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer by Simons, W.Robert, Jones, David, Buzdar, Aman

“…Background: In a recent trial of first-line therapy in 353 postmenopausal women with predominantly hormone receptor-positive advanced breast cancer (the North…”
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Escherichia coli translation initiation factor 3 discriminates the initiation codon in vivo by Sussman, J K, Simons, E L, Simons, R W

“…In a genetic selection designed to isolate Escherichia coli mutations that increase expression of the IS 10 transposase gene (tnp), we unexpectedly obtained…”
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Content validity of signs and symptoms measures with the EORTC core module in women with locally advanced or metastatic breast cancer (MBC): A phase II trial with eribulin mesylate by Simons, W. Robert

“…Abstract only e17576 Background: The EORTC-QLQ30 is the core quality of life (QOL) instrument developed by the European Organization for Research and Treatment…”
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The economic assessment of eribulin compared to treatment of physician's choice (TPC) in Australia by Jones, Trefor, Simons, W. Robert

“…Abstract only e17552 Background: The Eisai Metastatic Breast Cancer Study Assessing Physician’s Choice Versus E7389 (EMBRACE) established clinical benefits…”
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